12 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DRD5	D(1B) dopamine receptor. (477 aa)
	PTGER1	Prostaglandin E receptor 1. (402 aa)
	LOC465127	Dopamine receptor D5 pseudogene. (432 aa)
	GNAL	G protein subunit alpha L. (458 aa)
	GNB1	Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
	LOC104003639	Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa)
	DRD3	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity). (400 aa)
	GNAS	GNAS isoform 19. (1042 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GNAL	ENSPTRP00000026385	ENSPTRP00000077082	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.976
ADCY5	GNAS	ENSPTRP00000026385	ENSPTRP00000059419	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS isoform 19.	0.982
ADCY5	GNB1	ENSPTRP00000026385	ENSPTRP00000067330	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.776
ADCY5	GNG2	ENSPTRP00000026385	ENSPTRP00000065345	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.855
ADCY5	LOC104003639	ENSPTRP00000026385	ENSPTRP00000063078	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(s) subunit alpha.	0.902
DRD1	DRD3	ENSPTRP00000065588	ENSPTRP00000062496	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	0.689
DRD1	DRD5	ENSPTRP00000065588	ENSPTRP00000053705	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	D(1B) dopamine receptor.	0.623
DRD1	GNAL	ENSPTRP00000065588	ENSPTRP00000077082	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha L.	0.981
DRD1	GNAS	ENSPTRP00000065588	ENSPTRP00000059419	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	GNAS isoform 19.	0.989
DRD1	GNB1	ENSPTRP00000065588	ENSPTRP00000067330	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.859
DRD1	GNG2	ENSPTRP00000065588	ENSPTRP00000065345	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.804
DRD1	LOC104003639	ENSPTRP00000065588	ENSPTRP00000063078	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(s) subunit alpha.	0.917
DRD3	DRD1	ENSPTRP00000062496	ENSPTRP00000065588	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	0.689
DRD3	DRD5	ENSPTRP00000062496	ENSPTRP00000053705	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	D(1B) dopamine receptor.	0.515
DRD3	GNAL	ENSPTRP00000062496	ENSPTRP00000077082	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	G protein subunit alpha L.	0.566
DRD3	GNAS	ENSPTRP00000062496	ENSPTRP00000059419	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	GNAS isoform 19.	0.501
DRD3	GNB1	ENSPTRP00000062496	ENSPTRP00000067330	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.961
DRD3	GNG2	ENSPTRP00000062496	ENSPTRP00000065345	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.928
DRD3	LOC465127	ENSPTRP00000062496	ENSPTRP00000079338	D(3) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).	Dopamine receptor D5 pseudogene.	0.412
DRD5	DRD1	ENSPTRP00000053705	ENSPTRP00000065588	D(1B) dopamine receptor.	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	0.623