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CK820_G0035770 CK820_G0035770 ENSPTRP00000067301 ENSPTRP00000067301 NPFFR1 NPFFR1 SSTR1 SSTR1 SSTR3 SSTR3 KISS1R KISS1R SORCS1 SORCS1 GLRB GLRB PROK2 PROK2 SSTR5 SSTR5 LTB4R LTB4R RAPGEF2 RAPGEF2 NMU NMU NXPH2 NXPH2 NPB NPB PTH2 PTH2 HCRTR1 HCRTR1 SSTR2 SSTR2 GPR143 GPR143 MC2R MC2R GPR139 GPR139 PROKR2 PROKR2 NXPH3 NXPH3 TAC1 TAC1 CK820_G0021249 CK820_G0021249 NXPH1 NXPH1 SORCS3 SORCS3 TAC3 TAC3 GLRA2 GLRA2 ENSPTRP00000092281 ENSPTRP00000092281 CYSLTR2 CYSLTR2 SORCS2 SORCS2 PROKR1 PROKR1 PCSK1N PCSK1N NPPA NPPA NPPB NPPB OPRD1 OPRD1 SORT1 SORT1 RXFP4 RXFP4 PRLHR PRLHR PTGDR2 PTGDR2 GAL GAL GPR83 GPR83 SORL1 SORL1 NPFF NPFF GPR84 GPR84 NXPH4 NXPH4 NTS NTS TYRO3 TYRO3 NMB NMB NPW NPW AGRP AGRP HCRT HCRT PPY PPY GALR2 GALR2 UTS2R UTS2R ADCYAP1 ADCYAP1 GRP GRP GALR1 GALR1 NTSR2 NTSR2 UCN UCN TACR1 TACR1 C2AH2orf40 C2AH2orf40 NMUR1 NMUR1 PDYN PDYN SSTR4 SSTR4 CK820_G0037244 CK820_G0037244 GALR3 GALR3 MCHR1 MCHR1 GPR171 GPR171 GPR149 GPR149 TACR3 TACR3 QRFPR QRFPR NPY2R NPY2R NPY1R NPY1R NPY5R NPY5R GLRA3 GLRA3 RXFP3 RXFP3 GLRA1 GLRA1 NMUR2 NMUR2 HCRTR2 HCRTR2 MCHR2 MCHR2 NMBR NMBR NPY NPY NPVF NPVF CRCP CRCP GPR37 GPR37 PNOC PNOC PENK PENK QRFP QRFP GRPR GRPR CYSLTR1 CYSLTR1 GLRA4 GLRA4 TENM1 TENM1 BRS3 BRS3 GALP GALP GPR1 GPR1 OPRM1 OPRM1 PYY PYY NPFFR2 NPFFR2 TACR2 TACR2 NPSR1 NPSR1 CARTPT CARTPT NPY4R NPY4R NMS NMS POMC POMC NPBWR1 NPBWR1 C4H4orf48 C4H4orf48 RELA RELA NPS NPS SCG5 SCG5 LTB4R2 LTB4R2 ENSPTRP00000060289 ENSPTRP00000060289 CALCA CALCA ECEL1 ECEL1 NPBWR2 NPBWR2 CRCP-2 CRCP-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CK820_G0035770GLRA2 isoform 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (338 aa)
ENSPTRP00000067301annotation not available (92 aa)
NPFFR1Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family. (431 aa)
SSTR1Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa)
KISS1RKISS1R isoform 1. (401 aa)
SORCS1Sortilin related VPS10 domain containing receptor 1. (1168 aa)
GLRBGlycine receptor, beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
PROK2PROK2 isoform 2. (129 aa)
SSTR5SSTR5 isoform 1; Belongs to the G-protein coupled receptor 1 family. (320 aa)
LTB4RLeukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family. (352 aa)
RAPGEF2RAPGEF2 isoform 2. (1701 aa)
NMUNMU isoform 2. (174 aa)
NXPH2Neurexophilin; May be signaling molecules that resemble neuropeptides. (264 aa)
NPBNeuropeptide B. (125 aa)
PTH2Parathyroid hormone 2. (99 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
SSTR2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
GPR143G protein-coupled receptor 143. (404 aa)
MC2RMelanocortin 2 receptor. (297 aa)
GPR139G protein-coupled receptor 139. (353 aa)
PROKR2Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
NXPH3NXPH3 isoform 2. (354 aa)
TAC1TAC1 isoform 1. (134 aa)
CK820_G0021249NXPH1 isoform 5. (268 aa)
NXPH1Neurexophilin; May be signaling molecules that resemble neuropeptides. (271 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1222 aa)
TAC3TAC3 isoform 1. (121 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
ENSPTRP00000092281annotation not available (136 aa)
CYSLTR2Cysteinyl leukotriene receptor 2. (346 aa)
SORCS2SORCS2 isoform 2. (1159 aa)
PROKR1Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family. (393 aa)
PCSK1NProprotein convertase subtilisin/kexin type 1 inhibitor. (260 aa)
NPPANatriuretic peptide A. (153 aa)
NPPBNatriuretic peptide B. (134 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
SORT1SORT1 isoform 2. (831 aa)
RXFP4Relaxin family peptide/INSL5 receptor 4. (374 aa)
PRLHRProlactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
PTGDR2Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (396 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (422 aa)
SORL1Sortilin related receptor 1. (2214 aa)
NPFFPro-FMRFamide-related neuropeptide FF isoform X2. (113 aa)
GPR84G protein-coupled receptor 84. (396 aa)
NXPH4Neurexophilin; May be signaling molecules that resemble neuropeptides. (308 aa)
NTSNTS isoform 1. (170 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
NMBNMB isoform 1. (154 aa)
NPWNPW isoform 2. (230 aa)
AGRPAgouti related neuropeptide. (132 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (130 aa)
PPYPancreatic polypeptide. (95 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
UTS2RUrotensin 2 receptor; Belongs to the G-protein coupled receptor 1 family. (389 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
GRPGastrin releasing peptide. (138 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
NTSR2Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (416 aa)
UCNUCN isoform 1. (124 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
C2AH2orf40Chromosome 2 open reading frame 40. (148 aa)
NMUR1Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (426 aa)
PDYNPDYN isoform 1. (254 aa)
SSTR4Somatostatin receptor 4; Belongs to the G-protein coupled receptor 1 family. (388 aa)
CK820_G0037244NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
GALR3Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
MCHR1Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. (422 aa)
GPR171G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family. (319 aa)
GPR149G protein-coupled receptor 149. (731 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (465 aa)
QRFPRPyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa)
NPY2RNeuropeptide Y receptor type 2; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. (383 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
NPY5RNeuropeptide Y receptor type 5. (445 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
RXFP3Relaxin family peptide receptor 3. (469 aa)
GLRA1GLRA1 isoform 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
MCHR2Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family. (340 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
NPYNeuropeptide Y. (97 aa)
NPVFNeuropeptide VF precursor. (196 aa)
CRCPCRCP isoform 6. (148 aa)
GPR37G protein-coupled receptor 37. (613 aa)
PNOCPrepronociceptin. (176 aa)
PENKPENK isoform 3. (267 aa)
QRFPQRFP isoform 1. (136 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
BRS3Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (399 aa)
GALPGalanin like peptide. (116 aa)
GPR1G protein-coupled receptor 1. (355 aa)
OPRM1Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (476 aa)
PYYPYY isoform 1. (95 aa)
NPFFR2NPFFR2 isoform 1; Belongs to the G-protein coupled receptor 1 family. (522 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
CARTPTCART prepropeptide. (116 aa)
NPY4RNeuropeptide Y receptor Y4; Belongs to the G-protein coupled receptor 1 family. (375 aa)
NMSNMS isoform 1. (153 aa)
POMCProopiomelanocortin. (268 aa)
NPBWR1Neuropeptides B and W receptor 1; Belongs to the G-protein coupled receptor 1 family. (328 aa)
C4H4orf48Chromosome 4 C4orf48 homolog. (127 aa)
RELAV-rel reticuloendotheliosis viral oncogene homolog A (Avian). (551 aa)
NPSNeuropeptide S. (89 aa)
SCG5Neuroendocrine protein 7B2; Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro (By similarity). (212 aa)
LTB4R2Leukotriene B4 receptor 2. (389 aa)
ENSPTRP00000060289annotation not available (844 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
ECEL1Endothelin converting enzyme like 1. (775 aa)
NPBWR2Neuropeptides B and W receptor 2; Belongs to the G-protein coupled receptor 1 family. (333 aa)
CRCP-2CGRP receptor component. (148 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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