STRINGSTRING
CK820_G0005744 CK820_G0005744 MICAL2 MICAL2 MMP21 MMP21 DPCD DPCD NODAL NODAL ENKUR ENKUR DISP1 DISP1 VANGL2 VANGL2 APLNR APLNR FOLR1 FOLR1 FOXN4 FOXN4 ALG5 ALG5 DNAAF2 DNAAF2 HIF1A HIF1A PSEN1 PSEN1 ASB2 ASB2 MESP1 MESP1 IFT140 IFT140 TBX6 TBX6 RPGRIP1L RPGRIP1L NDRG4 NDRG4 PSKH1 PSKH1 FOXF1 FOXF1 GAS8 GAS8 TMEM107 TMEM107 CFAP52 CFAP52 NEK8 NEK8 CCDC103 CCDC103 MKS1 MKS1 TBX2 TBX2 DNAI2 DNAI2 FOXJ1 FOXJ1 CCDC40 CCDC40 CFAP53 CFAP53 DAND5 DAND5 MEGF8 MEGF8 DYNC2LI1 DYNC2LI1 ACVR2A ACVR2A BBS5 BBS5 IHH IHH DAW1 DAW1 MKKS MKKS KIF3B KIF3B IFT52 IFT52 SOX18 SOX18 TBX1 TBX1 AP1B1 AP1B1 TDGF1 TDGF1 ARL13B ARL13B IFT57 IFT57 NPHP3 NPHP3 PKD2 PKD2 PITX2 PITX2 BBS7 BBS7 DNAH5 DNAH5 HAND1 HAND1 NKX2-5 NKX2-5 SRF SRF AHI1 AHI1 TBXT TBXT DLL1 DLL1 TBX20 TBX20 SMO SMO SOX17 SOX17 LRRC6 LRRC6 FOXH1 FOXH1 CER1 CER1 IFT74 IFT74 DNAI1 DNAI1 ENG ENG NOTCH1 NOTCH1 OFD1 OFD1 DRC1 DRC1 SETDB2 SETDB2 DNAAF1 DNAAF1 DNAAF3 DNAAF3 PCSK6 PCSK6 C9H9orf116 C9H9orf116 ANKS6 ANKS6 RIPPLY2 RIPPLY2 LBX1 LBX1 ARMC4 ARMC4 HAND2 HAND2 CCDC39 CCDC39 WNT3A WNT3A FOXH1-2 FOXH1-2 TTC25 TTC25 NOTO NOTO BBS4 BBS4 CCDC151 CCDC151 CC2D2A CC2D2A DNAAF4 DNAAF4 C2CD3 C2CD3 PKD1L1 PKD1L1 ZIC3 ZIC3 TMEM107-2 TMEM107-2 SMO-2 SMO-2 GALNT11 GALNT11 PKD1L1-2 PKD1L1-2 NKX3-2 NKX3-2 IFT172 IFT172 RTTN RTTN LMLN2 LMLN2 SUFU SUFU DAAM2 DAAM2 DNAH11 DNAH11 BICC1 BICC1 TGFBR2 TGFBR2 FGF8 FGF8 SHH SHH ACVR1 ACVR1 NOTCH2 NOTCH2 GATA4 GATA4 ARL6 ARL6 GALNT11-2 GALNT11-2 ENSPTRP00000076822 ENSPTRP00000076822 ACVR2B ACVR2B DYNC2H1 DYNC2H1 CFAP45 CFAP45 CK820_G0021556 CK820_G0021556 LEFTY1 LEFTY1 CITED2 CITED2 FGF10 FGF10 TMED2 TMED2 STIL STIL TBX3 TBX3 WNT5A WNT5A RFX3 RFX3 CLUAP1 CLUAP1 ENSPTRP00000088702 ENSPTRP00000088702 ENSPTRP00000089747 ENSPTRP00000089747 MEF2C MEF2C SMAD3 SMAD3 LOC459608 LOC459608 C9H9orf116-2 C9H9orf116-2 OVOL2 OVOL2 C15H15orf65 C15H15orf65 TBC1D32 TBC1D32 MIB1 MIB1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CK820_G0005744MICALCL isoform 1. (689 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
MMP21Matrix metallopeptidase 21. (569 aa)
DPCDDeleted in primary ciliary dyskinesia homolog. (203 aa)
NODALNODAL isoform 2. (347 aa)
ENKUREnkurin, TRPC channel interacting protein. (256 aa)
DISP1Dispatched RND transporter family member 1. (1525 aa)
VANGL2Vang-like protein. (521 aa)
APLNRAPLNR isoform 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
FOLR1Folate receptor alpha. (257 aa)
FOXN4FOXN4 isoform 2. (517 aa)
ALG5Asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog. (386 aa)
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (837 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
IFT140Intraflagellar transport 140 homolog. (1471 aa)
TBX6T-box transcription factor 6. (443 aa)
RPGRIP1LRPGRIP1L isoform 4. (1269 aa)
NDRG4NDRG family member 4. (226 aa)
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa)
FOXF1FOXF1 isoform 1. (433 aa)
GAS8Growth arrest-specific 8. (537 aa)
TMEM107Transmembrane protein 107. (146 aa)
CFAP52Cilia and flagella associated protein 52. (620 aa)
NEK8NIMA related kinase 8. (692 aa)
CCDC103Coiled-coil domain containing 103. (242 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
TBX2T-box transcription factor 2. (712 aa)
DNAI2Dynein axonemal intermediate chain 2. (605 aa)
FOXJ1FOXJ1 isoform 1. (421 aa)
CCDC40CCDC40 isoform 3. (1142 aa)
CFAP53Cilia and flagella associated protein 53. (514 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
MEGF8Multiple EGF like domains 8. (2842 aa)
DYNC2LI1Dynein, cytoplasmic 2, light intermediate chain 1. (351 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
BBS5T0004560 isoform 1. (341 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
DAW1Dynein assembly factor with WD repeats 1. (415 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
IFT52Intraflagellar transport 52 homolog. (437 aa)
SOX18SOX18 isoform 1. (384 aa)
TBX1TBX1 isoform 1. (478 aa)
AP1B1AP complex subunit beta. (947 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
IFT57Intraflagellar transport 57 homolog. (429 aa)
NPHP3NPHP3 isoform 6. (1330 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
PITX2Homeobox protein. (324 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
DNAH5DNAH5 isoform 1. (4624 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
AHI1Abelson helper integration site 1. (1196 aa)
TBXTT-box transcription factor T. (435 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
TBX20T-box transcription factor 20. (447 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
SOX17SOX17 isoform 1. (416 aa)
LRRC6LRRC6 isoform 1. (466 aa)
FOXH1FOXH1 isoform 1. (365 aa)
CER1CER1 isoform 1. (267 aa)
IFT74Intraflagellar transport 74 homolog. (600 aa)
DNAI1Dynein axonemal intermediate chain 1. (703 aa)
ENGENG isoform 1. (658 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
OFD1OFD1 centriole and centriolar satellite protein. (1012 aa)
DRC1Dynein regulatory complex subunit 1. (740 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (719 aa)
DNAAF1Dynein assembly factor 1, axonemal. (725 aa)
DNAAF3Dynein axonemal assembly factor 3. (487 aa)
PCSK6PCSK6 isoform 3; Belongs to the peptidase S8 family. (968 aa)
C9H9orf116Chromosome 9 open reading frame 116. (136 aa)
ANKS6ANKS6 isoform 2. (871 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
LBX1Ladybird homeobox 1. (281 aa)
ARMC4ARMC4 isoform 2. (1004 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
CCDC39Coiled-coil domain containing 39. (941 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
FOXH1-2Forkhead box H1. (365 aa)
TTC25TTC25 isoform 1. (662 aa)
NOTONotochord homeobox. (251 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
CCDC151CCDC151 isoform 5. (623 aa)
CC2D2ACC2D2A isoform 1. (1627 aa)
DNAAF4Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility (By similarity). (420 aa)
C2CD3C2CD3 isoform 3. (2298 aa)
PKD1L1PKD1L1 isoform 1. (2857 aa)
ZIC3Zic family member 3. (466 aa)
TMEM107-2Transmembrane protein 107. (140 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (608 aa)
PKD1L1-2Polycystin 1 like 1, transient receptor potential channel interacting. (2857 aa)
NKX3-2NKX3-2 isoform 1. (333 aa)
IFT172Intraflagellar transport 172 homolog. (1767 aa)
RTTNRTTN isoform 1. (2230 aa)
LMLN2Leishmanolysin-like peptidase. (786 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (519 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
DNAH11Dynein axonemal heavy chain 11. (4518 aa)
BICC1Bicaudal C homolog 1. (1074 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
GATA4GATA binding protein 4. (443 aa)
ARL6ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (203 aa)
GALNT11-2Polypeptide N-acetylgalactosaminyltransferase 11. (608 aa)
ENSPTRP00000076822annotation not available (142 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
DYNC2H1DYNC2H1 isoform 4. (4314 aa)
CFAP45CFAP45 isoform 3. (551 aa)
CK820_G0021556TMED2 isoform 3. (200 aa)
LEFTY1Left-right determination factor. (366 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TMED2Transmembrane emp24 domain trafficking protein 2. (208 aa)
STILSTIL centriolar assembly protein. (1288 aa)
TBX3T-box transcription factor 3. (743 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
RFX3RFX3 isoform 4. (761 aa)
CLUAP1CLUAP1 isoform 5. (432 aa)
ENSPTRP00000088702annotation not available (170 aa)
ENSPTRP00000089747annotation not available (156 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SMAD3Mothers against decapentaplegic homolog. (442 aa)
LOC459608CFC1B isoform 2. (223 aa)
C9H9orf116-2Chromosome 9 C9orf116 homolog. (136 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
C15H15orf65Chromosome 15 C15orf65 homolog. (121 aa)
TBC1D32TBC1D32 isoform 4. (1298 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1014 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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