STRINGSTRING
ELAVL4 ELAVL4 CAMK2N1 CAMK2N1 NFATC4 NFATC4 NEUROD2 NEUROD2 DGKI DGKI NTF3 NTF3 CUX2 CUX2 MUSK MUSK FOXO6 FOXO6 RCAN1 RCAN1 NTAN1-2 NTAN1-2 GABRA5 GABRA5 CK820_G0040570-2 CK820_G0040570-2 GPI GPI BRAF-2 BRAF-2 ABCC8 ABCC8 EN1 EN1 SLC1A1 SLC1A1 VLDLR VLDLR MAPK8IP2 MAPK8IP2 BTBD9 BTBD9 AGER AGER SORCS3 SORCS3 ENSPTRP00000090382 ENSPTRP00000090382 MME MME MEF2C MEF2C SLC8A3 SLC8A3 PTEN PTEN SYNJ1-2 SYNJ1-2 TMOD2 TMOD2 GRIA1 GRIA1 ACTR2 ACTR2 YTHDF1 YTHDF1 SLC8A2 SLC8A2 ENSPTRP00000093022 ENSPTRP00000093022 CCL11 CCL11 NEDD9 NEDD9 PPT1 PPT1 NETO1 NETO1 NCSTN NCSTN APP APP EHMT2 EHMT2 MAP1A MAP1A HRH1 HRH1 CSMD2 CSMD2 EPHB2 EPHB2 ARC ARC JPH3 JPH3 DRD5 DRD5 SYNJ1 SYNJ1 APOE APOE NPS NPS GRIN2A GRIN2A RELN RELN CX3CR1 CX3CR1 KCNK2 KCNK2 ATXN1 ATXN1 JPH4 JPH4 GIT1 GIT1 TAFA2 TAFA2 PRKAR2B PRKAR2B BDNF BDNF ATXN1L ATXN1L SYT11 SYT11 CK820_G0012168 CK820_G0012168 SYNGAP1 SYNGAP1 ENSPTRP00000062833 ENSPTRP00000062833 LOC737549 LOC737549 ABCA7 ABCA7 INSR INSR ADAM2 ADAM2 ENSPTRP00000063424 ENSPTRP00000063424 CK820_G0054728 CK820_G0054728 SHANK3 SHANK3 TSC1 TSC1 EIF4A3 EIF4A3 DNAAF4 DNAAF4 AFF2 AFF2 RAG1 RAG1 PPP3CB PPP3CB CNTNAP2 CNTNAP2 ENSPTRP00000065012 ENSPTRP00000065012 HTT HTT ADCY1-2 ADCY1-2 DRD1 DRD1 SHANK1 SHANK1 FGF13 FGF13 CSMD1 CSMD1 SLC7A11 SLC7A11 PRKAR1B PRKAR1B DRD2 DRD2 EGFR EGFR ITGB1 ITGB1 ENSPTRP00000069792 ENSPTRP00000069792 NLGN3 NLGN3 ENSPTRP00000069902 ENSPTRP00000069902 NGF NGF PJA2 PJA2 LOC465632 LOC465632 SLC11A2 SLC11A2 ENSPTRP00000072166 ENSPTRP00000072166 AMFR AMFR LHX8 LHX8 ATAD1 ATAD1 ABL1 ABL1 CREB1 CREB1 NRXN1 NRXN1 TTBK1 TTBK1 ENSPTRP00000073361 ENSPTRP00000073361 ABI2 ABI2 PPP1R9B PPP1R9B TIFAB TIFAB SCN2A SCN2A CLN8 CLN8 DNAH11 DNAH11 LDLR LDLR PRNP PRNP DCANP1 DCANP1 SPECC1 SPECC1 SRC SRC HMGCR HMGCR NRXN2 NRXN2 UBE3A UBE3A ADCY8 ADCY8 S100B S100B NTRK2 NTRK2 IFT20 IFT20 FYN FYN RASGRF1 RASGRF1 ENSPTRP00000077947 ENSPTRP00000077947 PAFAH1B1 PAFAH1B1 FOS FOS NLGN4Y NLGN4Y CK820_G0040570 CK820_G0040570 SLC12A5 SLC12A5 LOC465127 LOC465127 STRA6 STRA6 BRAF BRAF CPEB3 CPEB3 CDK5 CDK5 PTN PTN CIC CIC ENSPTRP00000081061 ENSPTRP00000081061 MECP2 MECP2 ATP1A2 ATP1A2 CK820_G0057017 CK820_G0057017 ZNF385A ZNF385A PICALM PICALM ASIC1 ASIC1 NTRK1 NTRK1 KRAS KRAS MDK MDK KALRN KALRN SGK1 SGK1 B4GALT2 B4GALT2 ITGA8 ITGA8 ENSPTRP00000085676 ENSPTRP00000085676 VDAC1 VDAC1 CNTN2 CNTN2 ADGRF1 ADGRF1 CEBPB CEBPB GM2A GM2A SPG11 SPG11 SHISA7 SHISA7 ENSPTRP00000086334 ENSPTRP00000086334 TANC1 TANC1 PAIP2 PAIP2 FZD9 FZD9 PTPRZ1 PTPRZ1 BHLHB9 BHLHB9 TBR1 TBR1 TACR2 TACR2 NRXN3 NRXN3 GRIN1 GRIN1 NLGN4X NLGN4X PTCHD1 PTCHD1 GRPR GRPR DBH DBH BRINP1 BRINP1 CALB1 CALB1 CRH CRH POMK POMK DDHD2 DDHD2 NPTX2 NPTX2 ADCY1 ADCY1 PRKN PRKN VIP VIP EPM2A EPM2A TPBG TPBG ADGRB3 ADGRB3 PTCHD4 PTCHD4 SRF SRF TREM2 TREM2 GLP1R GLP1R ITPR3 ITPR3 PRRT1 PRRT1 RGS14 RGS14 NEUROG1 NEUROG1 CAMK4 CAMK4 PLK2 PLK2 UBA6 UBA6 KIT KIT ATP8A1 ATP8A1 GHSR GHSR BCHE BCHE ARL6IP5 ARL6IP5 ARF4 ARF4 SLC6A1 SLC6A1 OXTR OXTR EP300 EP300 PLA2G6 PLA2G6 GALR3 GALR3 MAPK1 MAPK1 CK820_G0037244 CK820_G0037244 ADNP ADNP SNAP25 SNAP25 PAK5 PAK5 PLCB1 PLCB1 LRRN4 LRRN4 OXT OXT CHST10 CHST10 TACR1 TACR1 UCN UCN ADCY3 ADCY3 PTRHD1 PTRHD1 BRSK1 BRSK1 PRKCG PRKCG KLK8 KLK8 NTF4 NTF4 CRTC1 CRTC1 SYT4 SYT4 GALR2 GALR2 TACO1 TACO1 RPS6KB1 RPS6KB1 NOG NOG ITGA3 ITGA3 GIP GIP C1QL1 C1QL1 KAT2A KAT2A THRA THRA PPP1R1B PPP1R1B NF1 NF1 SLC6A4 SLC6A4 SLC2A4 SLC2A4 DLG4 DLG4 ZZEF1 ZZEF1 CTNS CTNS SERPINF1 SERPINF1 NDRG4 NDRG4 NTAN1 NTAN1 NPTN NPTN FOXB1 FOXB1 GATM GATM B2M B2M PAK6 PAK6 EIF2AK4 EIF2AK4 MEIS2 MEIS2 CHRNA7 CHRNA7 LGMN LGMN KCNK10 KCNK10 PSEN1 PSEN1 HIF1A HIF1A HTR2A HTR2A PDE1B PDE1B ITGA5 ITGA5 AAAS AAAS RAPGEF3 RAPGEF3 GRIN2B GRIN2B CCND2 CCND2 NRGN NRGN TTC36 TTC36 GRM5 GRM5 SHANK2 SHANK2 NPAS4 NPAS4 FOSL1 FOSL1 KCNK4 KCNK4 FEN1 FEN1 TH TH RIC8A RIC8A EIF4EBP2 EIF4EBP2 EGR2 EGR2 DKK1 DKK1 BTG2 BTG2 PTGS2 PTGS2 TNR TNR LMX1A LMX1A CHRNB2 CHRNB2 GPR88 GPR88
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1. (78 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
DGKIDiacylglycerol kinase. (1079 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
CUX2Homeobox protein cut-like. (1489 aa)
MUSKMuscle associated receptor tyrosine kinase. (879 aa)
FOXO6FOXO6 isoform 2. (559 aa)
RCAN1RCAN1 isoform 6. (276 aa)
NTAN1-2N-terminal asparagine amidase. (310 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
CK820_G0040570-2PRKCZ isoform 4. (95 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (597 aa)
BRAF-2BRAF isoform 2. (766 aa)
ABCC8ABCC8 isoform 2. (1582 aa)
EN1Homeobox protein engrailed-like. (396 aa)
SLC1A1Amino acid transporter. (524 aa)
VLDLRVery low density lipoprotein receptor. (874 aa)
MAPK8IP2MAPK8IP2 isoform 2. (824 aa)
BTBD9BTB (POZ) domain containing 9. (612 aa)
AGERAdvanced glycosylation end-product specific receptor. (420 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1222 aa)
ENSPTRP00000090382annotation not available (493 aa)
MMEMembrane metallo-endopeptidase. (750 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
SYNJ1-2SYNJ1 isoform 4. (1585 aa)
TMOD2Tropomodulin 2 (Neuronal). (351 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (584 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
ENSPTRP00000093022annotation not available (563 aa)
CCL11C-C motif chemokine. (97 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
PPT1Palmitoyl-protein thioesterase 1. (335 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
NCSTNNCSTN isoform 1. (721 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1267 aa)
MAP1AMicrotubule associated protein 1A. (3041 aa)
HRH1Histamine H1 receptor; In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. (487 aa)
CSMD2CUB and Sushi multiple domains 2. (3631 aa)
EPHB2EPH receptor B2. (1055 aa)
ARCActivity-regulated cytoskeleton-associated protein. (396 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
DRD5D(1B) dopamine receptor. (477 aa)
SYNJ1SYNJ1 isoform 6. (1614 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
NPSNeuropeptide S. (89 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...] (1471 aa)
RELNRELN isoform 3. (3460 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
ATXN1ATXN1 isoform 2. (827 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
TAFA2TAFA chemokine like family member 2. (131 aa)
PRKAR2BProtein kinase, cAMP-dependent, regulatory, type II, beta. (418 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
ATXN1LATXN1L isoform 2. (689 aa)
SYT11Synaptotagmin 11. (431 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1345 aa)
ENSPTRP00000062833annotation not available (232 aa)
LOC737549Battenin. (418 aa)
ABCA7ABCA7 isoform 3. (1829 aa)
INSRTyrosine-protein kinase receptor. (1408 aa)
ADAM2ADAM2 isoform 1. (735 aa)
ENSPTRP00000063424annotation not available (1563 aa)
CK820_G0054728MECP2 isoform 14. (493 aa)
SHANK3SHANK3 isoform 2. (1744 aa)
TSC1TSC complex subunit 1. (1164 aa)
EIF4A3Uncharacterized protein; Belongs to the DEAD box helicase family. (413 aa)
DNAAF4Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility (By similarity). (420 aa)
AFF2AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure (By similarity); Belongs to the AF4 family. (1301 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (955 aa)
PPP3CBSerine/threonine-protein phosphatase. (526 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
ENSPTRP00000065012annotation not available (108 aa)
HTTHTT isoform 1. (3131 aa)
ADCY1-2Adenylate cyclase 1. (1119 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
SHANK1SHANK1 isoform 3. (2161 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
CSMD1CSMD1 isoform 2. (3565 aa)
SLC7A11Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSPTRP00000069792annotation not available (651 aa)
NLGN3NLGN3 isoform 5. (848 aa)
ENSPTRP00000069902annotation not available (306 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa)
PJA2Praja ring finger ubiquitin ligase 2. (708 aa)
LOC465632Voltage-dependent anion-selective channel protein 1 pseudogene. (246 aa)
SLC11A2SLC11A2 isoform 1. (590 aa)
ENSPTRP00000072166annotation not available (318 aa)
AMFRAutocrine motility factor receptor. (643 aa)
LHX8LHX8 isoform 2. (377 aa)
ATAD1ATPase family, AAA domain containing 1; Belongs to the AAA ATPase family. (363 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NRXN1NRXN1 isoform 9. (1547 aa)
TTBK1Tau tubulin kinase 1. (1321 aa)
ENSPTRP00000073361annotation not available (388 aa)
ABI2Abl interactor 2. (513 aa)
PPP1R9BProtein phosphatase 1, regulatory (Inhibitor) subunit 9B. (817 aa)
TIFABTIFAB isoform 1. (161 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
CLN8Ceroid-lipofuscinosis neuronal protein 8. (286 aa)
DNAH11Dynein axonemal heavy chain 11. (4518 aa)
LDLRLDLR isoform 7. (917 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa)
DCANP1LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (237 aa)
SPECC1Sperm antigen with calponin homology and coiled-coil domains 1. (1068 aa)
SRCTyrosine-protein kinase. (542 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
NRXN2NRXN2 isoform 2. (1712 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
S100BS100 calcium binding protein B; Belongs to the S-100 family. (94 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
IFT20IFT20 isoform 5. (164 aa)
FYNTyrosine-protein kinase. (537 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
ENSPTRP00000077947annotation not available (48 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
NLGN4YNeuroligin 4 Y-linked. (873 aa)
CK820_G0040570PRKCZ isoform 2. (457 aa)
SLC12A5Solute carrier family 12 member 5. (1139 aa)
LOC465127Dopamine receptor D5 pseudogene. (432 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
BRAFBRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (716 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
PTNPTN isoform 2. (172 aa)
CICCIC isoform 1. (2514 aa)
ENSPTRP00000081061annotation not available (107 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
CK820_G0057017CLN3 isoform 55. (42 aa)
ZNF385AZinc finger protein 385A. (414 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (674 aa)
ASIC1ASIC1 isoform 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (562 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
MDKMidkine (Neurite growth-promoting factor 2). (143 aa)
KALRNKalirin RhoGEF kinase. (2986 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
B4GALT2B4GALT2 isoform 6. (398 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ENSPTRP00000085676annotation not available (274 aa)
VDAC1Voltage-dependent anion channel 1. (289 aa)
CNTN2CNTN2 isoform 13. (1040 aa)
ADGRF1ADGRF1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (910 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
GM2AGM2 ganglioside activator. (194 aa)
SPG11SPG11 isoform 4. (2443 aa)
SHISA7SHISA7 isoform 2. (275 aa)
ENSPTRP00000086334annotation not available (320 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1861 aa)
PAIP2Poly(A) binding protein interacting protein 2. (124 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2315 aa)
BHLHB9Basic helix-loop-helix domain containing, class B, 9. (547 aa)
TBR1T-box brain transcription factor 1. (682 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)
NRXN3NRXN3 isoform 1. (1664 aa)
GRIN1Glutamate receptor, ionotropic, N-methyl D-aspartate 1. (845 aa)
NLGN4XNeuroligin 4 X-linked. (817 aa)
PTCHD1Patched domain containing 1. (888 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
DBHDopamine beta-hydroxylase. (617 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
CALB1CALB1 isoform 3. (261 aa)
CRHCorticotropin releasing hormone. (196 aa)
POMKProtein kinase-like protein SgK196. (350 aa)
DDHD2DDHD domain containing 2. (710 aa)
NPTX2Neuronal pentraxin 2. (431 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
VIPVasoactive intestinal peptide. (169 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
TPBGTrophoblast glycoprotein. (420 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
PTCHD4Patched domain containing 4. (846 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
ITPR3ITPR3 isoform 1. (2677 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
RGS14Regulator of G protein signaling 14. (566 aa)
NEUROG1NEUROG1 isoform 1. (237 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
UBA6Ubiquitin-like modifier-activating enzyme 6. (1052 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (643 aa)
ARL6IP5PRA1 family protein. (188 aa)
ARF4ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
EP300E1A binding protein p300. (2175 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
GALR3Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CK820_G0037244NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
ADNPActivity-dependent neuroprotector homeobox. (1102 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells; Belongs to the SNAP-25 family. (206 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LRRN4LRRN4 isoform 1. (740 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
CHST10Carbohydrate sulfotransferase. (356 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
UCNUCN isoform 1. (124 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
BRSK1BR serine/threonine kinase 1. (794 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
KLK8Kallikrein related peptidase 8; Belongs to the peptidase S1 family. (260 aa)
NTF4NTF4 isoform 1; Belongs to the NGF-beta family. (210 aa)
CRTC1CRTC1 isoform 1. (648 aa)
SYT4Synaptotagmin 4. (425 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
TACO1Translational activator of mitochondrially encoded cytochrome c oxidase I. (297 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ITGA3ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa)
GIPGastric inhibitory polypeptide. (153 aa)
C1QL1Complement C1q like 1. (258 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
THRAThyroid hormone receptor, alpha (Erythroblastic leukemia viral (V-erb-a) oncogene homolog, avian). (617 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (203 aa)
NF1Neurofibromin 1. (2839 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
SLC2A4SLC2A4 isoform 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (466 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
ZZEF1ZZEF1 isoform 1. (2962 aa)
CTNSCystinosin, lysosomal cystine transporter. (400 aa)
SERPINF1SERPINF1 isoform 1; Belongs to the serpin family. (418 aa)
NDRG4NDRG family member 4. (226 aa)
NTAN1N-terminal asparagine amidase. (310 aa)
NPTNNPTN isoform 2. (398 aa)
FOXB1FOXB1 isoform 3. (325 aa)
GATMGlycine amidinotransferase. (423 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (96 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
MEIS2MEIS2 isoform 1. (477 aa)
CHRNA7CHRNA7 isoform 7. (511 aa)
LGMNLGMN isoform 1. (433 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (543 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
PDE1BPhosphodiesterase. (536 aa)
ITGA5ITGA5 isoform 2; Belongs to the integrin alpha chain family. (1098 aa)
AAASAchalasia, adrenocortical insufficiency, alacrimia. (546 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
CCND2CCND2 isoform 1; Belongs to the cyclin family. (289 aa)
NRGNNRGN isoform 1. (78 aa)
TTC36TTC36 isoform 3. (206 aa)
GRM5Glutamate metabotropic receptor 5. (1210 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1849 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (393 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
THTyrosine hydroxylase. (528 aa)
RIC8AResistance to inhibitors of cholinesterase 8 homolog A. (530 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
EGR2Early growth response 2. (476 aa)
DKK1Dickkopf-like protein 1. (289 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
PTGS2Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
TNRTNR isoform 1. (1358 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
CHRNB2CHRNB2 isoform 2. (502 aa)
GPR88G protein-coupled receptor 88. (384 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (22%) [HD]