STRINGSTRING
PDPN PDPN FBLIM1 FBLIM1 FGR FGR PLEKHO1 PLEKHO1 SPTA1 SPTA1 PLXNA2 PLXNA2 BAMBI BAMBI RHOBTB1 RHOBTB1 GAS2 GAS2 F2 F2 RHOD RHOD EPS8 EPS8 RND1 RND1 ITGA7 ITGA7 RHOF RHOF RHOJ RHOJ CYFIP1 CYFIP1 FES FES CORO1A CORO1A CFDP1 CFDP1 FAM171A2 FAM171A2 FMNL1 FMNL1 GNA13 GNA13 SLC9A3R1 SLC9A3R1 MYL12B MYL12B EPB41L3 EPB41L3 PALM PALM PEAK3 PEAK3 DAPK3 DAPK3 PALM3 PALM3 HPN HPN ARHGAP15 ARHGAP15 VIL1 VIL1 HCK HCK BRWD1 BRWD1 CFAP410 CFAP410 RAC3 RAC3 CDC42EP1 CDC42EP1 FGD5 FGD5 LIMD1 LIMD1 PLXNB1 PLXNB1 RHOA RHOA DAG1 DAG1 PLXND1 PLXND1 P2RY1 P2RY1 WDR1 WDR1 KIT KIT KDR KDR MYO10 MYO10 RASA1 RASA1 RHOBTB3 RHOBTB3 ARAP3 ARAP3 FGD2 FGD2 PHIP PHIP BVES BVES ARHGAP18 ARHGAP18 GNA12 GNA12 SEPTIN7 SEPTIN7 CCL24 CCL24 STRIP2 STRIP2 DLC1 DLC1 PTK2B PTK2B FGD1 FGD1 PLXNA3 PLXNA3 CDC42SE1 CDC42SE1 WASF3 WASF3 EPB41 EPB41 DMTN DMTN PRPF40A PRPF40A TPM1 TPM1 FN1 FN1 ARHGEF18 ARHGEF18 CDC42SE2 CDC42SE2 WDPCP WDPCP RHOG RHOG CDC42EP5 CDC42EP5 FAM171B FAM171B RND3 RND3 SEMA4D SEMA4D ANXA1 ANXA1 FAM171A1 FAM171A1 ATP10A ATP10A CCL3 CCL3 ARAP1 ARAP1 PLXNA4 PLXNA4 ENSPTRP00000060141 ENSPTRP00000060141 FGD3 FGD3 KIF3A KIF3A KIF3A-2 KIF3A-2 LPAR1 LPAR1 MYL12A MYL12A BAIAP2 BAIAP2 CCL13 CCL13 MYH14 MYH14 SEMA3E SEMA3E CK820_G0050308 CK820_G0050308 RHOB RHOB DLG1 DLG1 TBCCD1 TBCCD1 LST1 LST1 ENSPTRP00000067474 ENSPTRP00000067474 ENSPTRP00000067724 ENSPTRP00000067724 TAOK2 TAOK2 RHOD-2 RHOD-2 RAC1 RAC1 SEMA4A SEMA4A CCL2 CCL2 PALM2AKAP2 PALM2AKAP2 ENSPTRP00000069052 ENSPTRP00000069052 RND2 RND2 RAC2 RAC2 MYH10 MYH10 PALMD PALMD MARK2 MARK2 ENSPTRP00000070989 ENSPTRP00000070989 CCL24-2 CCL24-2 RHOC RHOC RDX RDX SLC26A5 SLC26A5 SYNE3 SYNE3 ENSPTRP00000074085 ENSPTRP00000074085 CDC42EP2 CDC42EP2 PARVB PARVB ARHGAP35 ARHGAP35 DIAPH1 DIAPH1 ERMN ERMN C15H15orf62 C15H15orf62 PLXNC1 PLXNC1 PLXNB2 PLXNB2 FYN FYN COCH COCH MYH9 MYH9 LOC745935 LOC745935 RHOBTB2 RHOBTB2 ENSPTRP00000079145 ENSPTRP00000079145 LOC100615440 LOC100615440 RHOQ RHOQ ZMPSTE24 ZMPSTE24 FERMT2 FERMT2 CSF1R CSF1R DNMBP DNMBP FMNL3 FMNL3 SH3KBP1 SH3KBP1 CRK CRK MKLN1 MKLN1 FGD4 FGD4 PTK2 PTK2 RAC1-2 RAC1-2 FMNL2 FMNL2 SHROOM3 SHROOM3 ENSPTRP00000085851 ENSPTRP00000085851 ENSPTRP00000085929 ENSPTRP00000085929 F11R F11R ENSPTRP00000086247 ENSPTRP00000086247 MSN MSN HEXB HEXB RHOU RHOU ENSPTRP00000088414 ENSPTRP00000088414 STRIP2-2 STRIP2-2 PLXNA1 PLXNA1 PARVA PARVA PALM2AKAP2-2 PALM2AKAP2-2 BRWD3 BRWD3 FGD6 FGD6 ITGB2 ITGB2 RHOH RHOH PLXNB3 PLXNB3 CCL11 CCL11 CDC42EP3 CDC42EP3 EZR EZR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDPNPDPN isoform 3. (238 aa)
FBLIM1Filamin binding LIM protein 1. (374 aa)
FGRTyrosine-protein kinase. (529 aa)
PLEKHO1Pleckstrin homology domain containing, family O member 1. (409 aa)
SPTA1SPTA1 isoform 1. (2419 aa)
PLXNA2PLXNA2 isoform 1. (1909 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
RHOBTB1Rho-related BTB domain containing 1. (696 aa)
GAS2GAS2 isoform 1. (314 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
RHODRas homolog gene family, member D. (210 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
RND1RND1 isoform 1. (163 aa)
ITGA7ITGA7 isoform 6; Belongs to the integrin alpha chain family. (1181 aa)
RHOFRas homolog family member F, filopodia associated. (211 aa)
RHOJRas homolog gene family, member J. (214 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CFDP1Craniofacial development protein 1. (299 aa)
FAM171A2Family with sequence similarity 171 member A2. (826 aa)
FMNL1FMNL1 isoform 1. (1100 aa)
GNA13Guanine nucleotide binding protein (G protein), alpha 13. (377 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
MYL12BMyosin light chain 12B. (172 aa)
EPB41L3EPB41L3 isoform 7. (1087 aa)
PALMPALM isoform 3. (387 aa)
PEAK3PEAK family member 3. (473 aa)
DAPK3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
PALM3PALM3 isoform 1. (656 aa)
HPNHPN isoform 1; Belongs to the peptidase S1 family. (417 aa)
ARHGAP15Rho GTPase activating protein 15. (475 aa)
VIL1VIL1 isoform 1. (827 aa)
HCKTyrosine-protein kinase. (526 aa)
BRWD1Bromodomain and WD repeat domain containing 1. (2320 aa)
CFAP410Cilia and flagella associated protein 410. (376 aa)
RAC3Ras-related C3 botulinum toxin substrate 3 (Rho family, small GTP binding protein Rac3). (205 aa)
CDC42EP1CDC42 effector protein (Rho GTPase binding) 1. (391 aa)
FGD5FYVE, RhoGEF and PH domain containing 5. (1462 aa)
LIMD1LIM domains containing 1. (676 aa)
PLXNB1PLXNB1 isoform 1. (2135 aa)
RHOARas homolog family member A. (193 aa)
DAG1Dystroglycan 1 (Dystrophin-associated glycoprotein 1). (895 aa)
PLXND1PLXND1 isoform 1. (1925 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
WDR1WD repeat domain 1. (606 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
MYO10MYO10 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2069 aa)
RASA1RAS p21 protein activator (GTPase activating protein) 1. (1047 aa)
RHOBTB3Rho-related BTB domain containing 3. (611 aa)
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1546 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (655 aa)
PHIPPHIP isoform 1. (1823 aa)
BVESBlood vessel epicardial substance. (360 aa)
ARHGAP18Rho GTPase activating protein 18. (663 aa)
GNA12Guanine nucleotide binding protein (G protein) alpha 12. (381 aa)
SEPTIN7Septin-7; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-li [...] (447 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
STRIP2Striatin interacting protein 2. (834 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (961 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
CDC42SE1CDC42 small effector 1. (79 aa)
WASF3WH2 domain-containing protein. (502 aa)
EPB41Erythrocyte membrane protein band 4.1. (864 aa)
DMTNDematin actin binding protein. (405 aa)
PRPF40APRP40 pre-mRNA processing factor 40 homolog A. (930 aa)
TPM1TPM1 isoform 3; Belongs to the tropomyosin family. (326 aa)
FN1FN1 isoform 1. (2477 aa)
ARHGEF18Rho guanine nucleotide exchange factor 18 isoform X6. (1015 aa)
CDC42SE2CDC42 small effector 2. (84 aa)
WDPCPWDPCP isoform 2. (746 aa)
RHOGRas homolog gene family, member G (Rho G). (191 aa)
CDC42EP5CDC42 effector protein (Rho GTPase binding) 5. (148 aa)
FAM171BFamily with sequence similarity 171, member B. (825 aa)
RND3Rho family GTPase 3. (244 aa)
SEMA4DSEMA4D isoform 13; Belongs to the semaphorin family. (862 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa)
FAM171A1Family with sequence similarity 171, member A1. (1022 aa)
ATP10APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1499 aa)
CCL3C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (92 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1419 aa)
PLXNA4PLXNA4 isoform 1. (1894 aa)
ENSPTRP00000060141annotation not available (172 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (725 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (701 aa)
KIF3A-2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
MYL12AMyosin light chain 12A. (177 aa)
BAIAP2BAI1 associated protein 2. (553 aa)
CCL13C-C motif chemokine. (98 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
SEMA3ESEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
CK820_G0050308T0178126 isoform 1. (382 aa)
RHOBRas homolog gene family, member B. (286 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
TBCCD1TBCC domain containing 1. (557 aa)
LST1Leukocyte specific transcript 1. (104 aa)
ENSPTRP00000067474annotation not available (148 aa)
ENSPTRP00000067724annotation not available (96 aa)
TAOK2TAOK2 isoform 1. (1235 aa)
RHOD-2Ras homolog family member D. (194 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
SEMA4ASEMA4A isoform 10; Belongs to the semaphorin family. (761 aa)
CCL2C-C motif chemokine. (109 aa)
PALM2AKAP2PALM2 and AKAP2 fusion. (411 aa)
ENSPTRP00000069052annotation not available (151 aa)
RND2Rho family GTPase 2. (227 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). (207 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
PALMDPALMD isoform 1. (552 aa)
MARK2Non-specific serine/threonine protein kinase. (668 aa)
ENSPTRP00000070989annotation not available (102 aa)
CCL24-2C-C motif chemokine ligand 24. (119 aa)
RHOCRho-related GTP-binding protein RhoC isoform X1. (196 aa)
RDXRDX isoform 3. (609 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (744 aa)
SYNE3Spectrin repeat containing nuclear envelope family member 3. (975 aa)
ENSPTRP00000074085annotation not available (188 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (210 aa)
PARVBBeta-parvin isoform X1. (397 aa)
ARHGAP35Glucocorticoid receptor DNA binding factor 1. (1519 aa)
DIAPH1DIAPH1 isoform 4. (1278 aa)
ERMNERMN isoform 2. (297 aa)
C15H15orf62Chromosome 15 C15orf62 homolog. (175 aa)
PLXNC1PLXNC1 isoform 1. (1568 aa)
PLXNB2PLXNB2 isoform 1. (1838 aa)
FYNTyrosine-protein kinase. (537 aa)
COCHCOCH isoform 2. (550 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
LOC745935C-C motif chemokine. (87 aa)
RHOBTB2Rho related BTB domain containing 2. (749 aa)
ENSPTRP00000079145annotation not available (395 aa)
LOC100615440Moesin pseudogene. (516 aa)
RHOQRas homolog gene family, member Q. (205 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (480 aa)
FERMT2Fermitin family member 2. (706 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
DNMBPDynamin binding protein. (1577 aa)
FMNL3FMNL3 isoform 2. (1027 aa)
SH3KBP1SH3KBP1 isoform 2. (665 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
MKLN1Muskelin 1, intracellular mediator containing kelch motifs. (735 aa)
FGD4FGD4 isoform 1. (914 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
FMNL2FMNL2 isoform 1. (1093 aa)
SHROOM3SHROOM3 isoform 1. (1945 aa)
ENSPTRP00000085851annotation not available (120 aa)
ENSPTRP00000085929annotation not available (241 aa)
F11RF11R isoform 1. (322 aa)
ENSPTRP00000086247annotation not available (513 aa)
MSNMSN isoform 1. (577 aa)
HEXBBeta-hexosaminidase. (557 aa)
RHOURas homolog family member U. (258 aa)
ENSPTRP00000088414annotation not available (529 aa)
STRIP2-2Striatin interacting protein 2. (834 aa)
PLXNA1PLXNA1 isoform 1. (1915 aa)
PARVAPARVA isoform 1. (412 aa)
PALM2AKAP2-2PALM2-AKAP2 fusion. (953 aa)
BRWD3Bromodomain and WD repeat domain containing 3. (1802 aa)
FGD6FGD6 isoform 1. (1430 aa)
ITGB2Integrin beta. (863 aa)
RHOHRHOH isoform 10. (191 aa)
PLXNB3PLXNB3 isoform 1. (1932 aa)
CCL11C-C motif chemokine. (97 aa)
CDC42EP3CDC42 effector protein (Rho GTPase binding) 3. (254 aa)
EZREZR isoform 1. (671 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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