28 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPTRP00000066534	annotation not available (384 aa)
	ENSPTRP00000065447	annotation not available (354 aa)
	KYAT1	Kynurenine aminotransferase 1. (516 aa)
	BCAT1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
	SPTLC3	Serine palmitoyltransferase, long chain base subunit 3. (552 aa)
	ACCSL	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like. (568 aa)
	GFPT1	Glutamine--fructose-6-phosphate transaminase 1. (699 aa)
	GPT	Glutamic--pyruvic transaminase. (496 aa)
	KYAT3	Cysteine conjugate-beta lyase 2. (454 aa)
	GOT1	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (413 aa)
	OAT	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
	GPT2	Glutamic pyruvate transaminase (Alanine aminotransferase) 2. (523 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	TAT	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
	BCAT2	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
	MGAT4A	MGAT4A isoform 1. (535 aa)
	AGXT	Serine--pyruvate aminotransferase. (367 aa)
	AMT	Aminomethyltransferase, mitochondrial isoform X2. (403 aa)
	ETNPPL	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (499 aa)
	AADAT	Aminoadipate aminotransferase. (425 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
	GFPT2	Glutamine-fructose-6-phosphate transaminase 2. (682 aa)
	GOT1L1	GOT1L1 isoform 1. (415 aa)
	ENSPTRP00000082047	annotation not available (353 aa)
	ENSPTRP00000071311	annotation not available (380 aa)
	PHYKPL	Alanine-glyoxylate aminotransferase 2-like 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	ABAT	ENSPTRP00000028475	ENSPTRP00000013232	Aminoadipate aminotransferase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.401
AADAT	AGXT	ENSPTRP00000028475	ENSPTRP00000022452	Aminoadipate aminotransferase.	Serine--pyruvate aminotransferase.	0.418
AADAT	AGXT2	ENSPTRP00000028475	ENSPTRP00000028785	Aminoadipate aminotransferase.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.426
AADAT	BCAT1	ENSPTRP00000028475	ENSPTRP00000062905	Aminoadipate aminotransferase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.898
AADAT	BCAT2	ENSPTRP00000028475	ENSPTRP00000019306	Aminoadipate aminotransferase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.898
AADAT	ETNPPL	ENSPTRP00000028475	ENSPTRP00000028096	Aminoadipate aminotransferase.	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.401
AADAT	GOT1	ENSPTRP00000028475	ENSPTRP00000004968	Aminoadipate aminotransferase.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.461
AADAT	GOT2	ENSPTRP00000028475	ENSPTRP00000013976	Aminoadipate aminotransferase.	Aspartate aminotransferase.	0.428
AADAT	KYAT1	ENSPTRP00000028475	ENSPTRP00000063694	Aminoadipate aminotransferase.	Kynurenine aminotransferase 1.	0.968
AADAT	KYAT3	ENSPTRP00000028475	ENSPTRP00000001612	Aminoadipate aminotransferase.	Cysteine conjugate-beta lyase 2.	0.935
AADAT	PHYKPL	ENSPTRP00000028475	ENSPTRP00000067067	Aminoadipate aminotransferase.	Alanine-glyoxylate aminotransferase 2-like 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.401
ABAT	AADAT	ENSPTRP00000013232	ENSPTRP00000028475	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminoadipate aminotransferase.	0.401
ABAT	AGXT	ENSPTRP00000013232	ENSPTRP00000022452	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine--pyruvate aminotransferase.	0.556
ABAT	AGXT2	ENSPTRP00000013232	ENSPTRP00000028785	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.938
ABAT	GOT1	ENSPTRP00000013232	ENSPTRP00000004968	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.748
ABAT	GOT1L1	ENSPTRP00000013232	ENSPTRP00000093290	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	GOT1L1 isoform 1.	0.449
ACCSL	BCAT1	ENSPTRP00000048145	ENSPTRP00000062905	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.442
ACCSL	BCAT2	ENSPTRP00000048145	ENSPTRP00000019306	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.442
AGXT	AADAT	ENSPTRP00000022452	ENSPTRP00000028475	Serine--pyruvate aminotransferase.	Aminoadipate aminotransferase.	0.418
AGXT	ABAT	ENSPTRP00000022452	ENSPTRP00000013232	Serine--pyruvate aminotransferase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.556