27 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSPH-2	Phosphoserine phosphatase. (225 aa)
	DHFR2	DHFR2 isoform 2. (186 aa)
	ENSPTRP00000092611	annotation not available (106 aa)
	ENSPTRP00000092702	annotation not available (482 aa)
	CTH	Cystathionase (Cystathionine gamma-lyase). (405 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (573 aa)
	SEPHS1	Selenophosphate synthetase 1. (385 aa)
	MTHFD1	MTHFD1 isoform 1. (1020 aa)
	SRR	Serine racemase. (340 aa)
	ENSPTRP00000065447	annotation not available (354 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	PSPH	Phosphoserine phosphatase. (225 aa)
	DHFR	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
	SERINC5	Serine incorporator 5. (461 aa)
	ENSPTRP00000066929	annotation not available (132 aa)
	LOC465383	Uncharacterized protein. (210 aa)
	LOC465383-2	Uncharacterized protein. (72 aa)
	ENSPTRP00000070671	annotation not available (362 aa)
	SHMT1	Serine hydroxymethyltransferase 1. (483 aa)
	ENSPTRP00000082047	annotation not available (353 aa)
	ENSPTRP00000082302	annotation not available (814 aa)
	CBS	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (551 aa)
	SERINC3	Serine incorporator 3. (473 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	AGXT	Serine--pyruvate aminotransferase. (367 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGXT	AGXT2	ENSPTRP00000022452	ENSPTRP00000028785	Serine--pyruvate aminotransferase.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.901
AGXT	ENSPTRP00000066929	ENSPTRP00000022452	ENSPTRP00000066929	Serine--pyruvate aminotransferase.	annotation not available	0.694
AGXT	ENSPTRP00000092611	ENSPTRP00000022452	ENSPTRP00000092611	Serine--pyruvate aminotransferase.	annotation not available	0.802
AGXT	HAO1	ENSPTRP00000022452	ENSPTRP00000022702	Serine--pyruvate aminotransferase.	Hydroxyacid oxidase 1.	0.746
AGXT	LOC465383	ENSPTRP00000022452	ENSPTRP00000066047	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.694
AGXT	LOC465383-2	ENSPTRP00000022452	ENSPTRP00000068603	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.694
AGXT	PHGDH	ENSPTRP00000022452	ENSPTRP00000002013	Serine--pyruvate aminotransferase.	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.736
AGXT	PSPH	ENSPTRP00000022452	ENSPTRP00000032820	Serine--pyruvate aminotransferase.	Phosphoserine phosphatase.	0.694
AGXT	PSPH-2	ENSPTRP00000022452	ENSPTRP00000067271	Serine--pyruvate aminotransferase.	Phosphoserine phosphatase.	0.694
AGXT	SHMT1	ENSPTRP00000022452	ENSPTRP00000076664	Serine--pyruvate aminotransferase.	Serine hydroxymethyltransferase 1.	0.828
AGXT	SHMT2	ENSPTRP00000022452	ENSPTRP00000063004	Serine--pyruvate aminotransferase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.783
AGXT2	AGXT	ENSPTRP00000028785	ENSPTRP00000022452	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine--pyruvate aminotransferase.	0.901
AGXT2	CTH	ENSPTRP00000028785	ENSPTRP00000001478	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Cystathionase (Cystathionine gamma-lyase).	0.931
AGXT2	HAO1	ENSPTRP00000028785	ENSPTRP00000022702	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Hydroxyacid oxidase 1.	0.862
AGXT2	SHMT2	ENSPTRP00000028785	ENSPTRP00000063004	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.919
CBS	CTH	ENSPTRP00000024013	ENSPTRP00000001478	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Cystathionase (Cystathionine gamma-lyase).	0.999
CBS	ENSPTRP00000082302	ENSPTRP00000024013	ENSPTRP00000082302	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	annotation not available	0.488
CBS	ENSPTRP00000092611	ENSPTRP00000024013	ENSPTRP00000092611	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	annotation not available	0.535
CBS	LOC465383-2	ENSPTRP00000024013	ENSPTRP00000068603	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	Uncharacterized protein.	0.930
CBS	MTHFD1	ENSPTRP00000024013	ENSPTRP00000010916	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	MTHFD1 isoform 1.	0.655