STRINGSTRING
STIL STIL TBX3 TBX3 WNT5A WNT5A TDRD6 TDRD6 PTCH1 PTCH1 WT1 WT1 WNT8A WNT8A ENSPTRP00000088702 ENSPTRP00000088702 ENSPTRP00000089747 ENSPTRP00000089747 FOXA2 FOXA2 NODAL NODAL BMPR1A BMPR1A TDRD1 TDRD1 GDF3 GDF3 WNT1 WNT1 BMP4 BMP4 OTX2 OTX2 MNS1 MNS1 SMAD6 SMAD6 MESP1 MESP1 MESP2 MESP2 TBX6 TBX6 WNT3 WNT3 SMAD4 SMAD4 SIX3 SIX3 SIX2 SIX2 VAX2 VAX2 FZD5 FZD5 AURKA AURKA TDGF1 TDGF1 ARL13B ARL13B PITX2 PITX2 NEUROG1 NEUROG1 CDX1 CDX1 MDFI MDFI SRF SRF HEY2 HEY2 AHI1 AHI1 TBXT TBXT DLL1 DLL1 SMO SMO STC1 STC1 CER1 CER1 NOTCH1 NOTCH1 BCOR BCOR CDX4 CDX4 LDB1 LDB1 TASOR TASOR TDRD15 TDRD15 AXIN1 AXIN1 SETDB2 SETDB2 ETS2 ETS2 DDIT3 DDIT3 NRARP NRARP CTNNB1 CTNNB1 PCSK6 PCSK6 TDRD7 TDRD7 RIPPLY1 RIPPLY1 C2BH2orf66 C2BH2orf66 RIPPLY2 RIPPLY2 SFRP1 SFRP1 LHX1 LHX1 CXXC4 CXXC4 EPB41L5 EPB41L5 FAM76A FAM76A ENSPTRP00000062011 ENSPTRP00000062011 SMAD2 SMAD2 C2CD3 C2CD3 PKD1L1 PKD1L1 ENSPTRP00000064416 ENSPTRP00000064416 WNT7A WNT7A TDRKH TDRKH PAX6 PAX6 MDFI-2 MDFI-2 ZIC3 ZIC3 TTC8 TTC8 PLD6 PLD6 SMO-2 SMO-2 BASP1 BASP1 PKD1L1-2 PKD1L1-2 CDX2 CDX2 IFT172 IFT172 WLS WLS FAM76B FAM76B TIFAB TIFAB IRX4 IRX4 KDM6A KDM6A HSPB11 HSPB11 MTHFSD MTHFSD DCANP1 DCANP1 SHH SHH NOTCH2 NOTCH2 TDRD10 TDRD10 ENSPTRP00000076822 ENSPTRP00000076822 CK820_G0021556 CK820_G0021556 BCOR-2 BCOR-2 WNT3-2 WNT3-2 WNT6 WNT6 BMP4-2 BMP4-2 FRS2 FRS2 ENSPTRP00000092743 ENSPTRP00000092743 TDRD5 TDRD5 RNF2 RNF2 SKI SKI WDR77 WDR77 PGAP1 PGAP1 CITED2 CITED2 CHRDL1 CHRDL1 COBL COBL FGF10 FGF10 ENSPTRP00000083658 ENSPTRP00000083658 TMED2 TMED2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STILSTIL centriolar assembly protein. (1288 aa)
TBX3T-box transcription factor 3. (743 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TDRD6Tudor domain containing 6. (2097 aa)
PTCH1PTCH1 isoform 8. (1428 aa)
WT1WT1 transcription factor. (514 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
ENSPTRP00000088702annotation not available (170 aa)
ENSPTRP00000089747annotation not available (156 aa)
FOXA2FOXA2 isoform 1. (464 aa)
NODALNODAL isoform 2. (347 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TDRD1Tudor domain containing 1. (1189 aa)
GDF3Growth differentiation factor 3. (364 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
MNS1Meiosis-specific nuclear structural protein 1. (495 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (268 aa)
MESP2Mesoderm posterior bHLH transcription factor 2. (389 aa)
TBX6T-box transcription factor 6. (443 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SIX3SIX homeobox 3. (331 aa)
SIX2SIX homeobox 2. (291 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
AURKASerine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
PITX2Homeobox protein. (324 aa)
NEUROG1NEUROG1 isoform 1. (237 aa)
CDX1CDX1 isoform 1. (265 aa)
MDFIMyoD family inhibitor. (246 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif 2. (337 aa)
AHI1Abelson helper integration site 1. (1196 aa)
TBXTT-box transcription factor T. (435 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
STC1Stanniocalcin 1. (247 aa)
CER1CER1 isoform 1. (267 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
BCORBCL6 corepressor. (1755 aa)
CDX4Caudal type homeobox 4. (284 aa)
LDB1LIM domain binding 1. (411 aa)
TASORTranscription activation suppressor. (1609 aa)
TDRD15Tudor domain containing 15. (1934 aa)
AXIN1AXIN1 isoform 2. (859 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (719 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
PCSK6PCSK6 isoform 3; Belongs to the peptidase S8 family. (968 aa)
TDRD7Tudor domain containing 7. (1098 aa)
RIPPLY1Ripply transcriptional repressor 1. (151 aa)
C2BH2orf66Chromosome 2B C2orf66 homolog. (117 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
CXXC4CXXC4 isoform 2. (366 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
FAM76AFamily with sequence similarity 76 member A. (341 aa)
ENSPTRP00000062011annotation not available (389 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
C2CD3C2CD3 isoform 3. (2298 aa)
PKD1L1PKD1L1 isoform 1. (2857 aa)
ENSPTRP00000064416annotation not available (502 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
TDRKHTudor and KH domain containing. (605 aa)
PAX6PAX6 isoform 13. (436 aa)
MDFI-2MyoD family inhibitor. (246 aa)
ZIC3Zic family member 3. (466 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
PLD6Phospholipase D family member 6. (252 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
BASP1Brain abundant, membrane attached signal protein 1. (226 aa)
PKD1L1-2Polycystin 1 like 1, transient receptor potential channel interacting. (2857 aa)
CDX2Caudal type homeobox 2. (313 aa)
IFT172Intraflagellar transport 172 homolog. (1767 aa)
WLSWnt ligand secretion mediator. (543 aa)
FAM76BFamily with sequence similarity 76, member B. (339 aa)
TIFABTIFAB isoform 1. (161 aa)
IRX4IRX4 isoform 3. (543 aa)
KDM6AKDM6A isoform 1. (1453 aa)
HSPB11Heat shock protein family B (small) member 11. (214 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (383 aa)
DCANP1LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (237 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
TDRD10Tudor domain containing 10. (366 aa)
ENSPTRP00000076822annotation not available (142 aa)
CK820_G0021556TMED2 isoform 3. (200 aa)
BCOR-2BCL6 corepressor. (1755 aa)
WNT3-2Wnt family member 3. (290 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
ENSPTRP00000092743annotation not available (379 aa)
TDRD5Tudor domain containing 5. (1035 aa)
RNF2Ring finger protein 2. (336 aa)
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
WDR77Methylosome protein 50. (342 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
CHRDL1CHRDL1 isoform 3. (458 aa)
COBLCordon-bleu WH2 repeat protein. (1333 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSPTRP00000083658annotation not available (282 aa)
TMED2Transmembrane emp24 domain trafficking protein 2. (208 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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