83 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCANP1	LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (237 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	TDRD10	Tudor domain containing 10. (366 aa)
	ENSPTRP00000076822	annotation not available (142 aa)
	CK820_G0021556	TMED2 isoform 3. (200 aa)
	TBXT	T-box transcription factor T. (435 aa)
	NEUROG1	NEUROG1 isoform 1. (237 aa)
	SMAD1	Mothers against decapentaplegic homolog. (469 aa)
	TDGF1	Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa)
	DOP1B	Dopey family member 2. (2298 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	MEOX1	Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independen [...] (254 aa)
	TBX6	T-box transcription factor 6. (443 aa)
	MESP2	Mesoderm posterior bHLH transcription factor 2. (389 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (268 aa)
	SMAD6	Mothers against decapentaplegic homolog. (496 aa)
	MEIS2	MEIS2 isoform 1. (477 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	GDF3	Growth differentiation factor 3. (364 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	TDRD1	Tudor domain containing 1. (1189 aa)
	NODAL	NODAL isoform 2. (347 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	DISP1	Dispatched RND transporter family member 1. (1525 aa)
	TDRD5	Tudor domain containing 5. (1035 aa)
	SEMA3F	SEMA3F isoform 2; Belongs to the semaphorin family. (785 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	SATB2	DNA-binding protein SATB. (733 aa)
	PGAP1	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
	CHRDL1	CHRDL1 isoform 3. (458 aa)
	COBL	Cordon-bleu WH2 repeat protein. (1333 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	TMED2	Transmembrane emp24 domain trafficking protein 2. (208 aa)
	STIL	STIL centriolar assembly protein. (1288 aa)
	TBX3	T-box transcription factor 3. (743 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	TDRD6	Tudor domain containing 6. (2097 aa)
	PTCH1	PTCH1 isoform 8. (1428 aa)
	WT1	WT1 transcription factor. (514 aa)
	ENSPTRP00000088702	annotation not available (170 aa)
	LAMA5	Laminin, alpha 5. (2203 aa)
	ENSPTRP00000089747	annotation not available (156 aa)
	EFNB1	EFNB1 isoform 1; Belongs to the ephrin family. (346 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (521 aa)
	SMAD3	Mothers against decapentaplegic homolog. (442 aa)
	SIM2	SIM bHLH transcription factor 2. (667 aa)
	MEOX2	Mesenchyme homeobox 2. (302 aa)
	TASOR	Transcription activation suppressor. (1609 aa)
	TDRD15	Tudor domain containing 15. (1934 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	PCSK6	PCSK6 isoform 3; Belongs to the peptidase S8 family. (968 aa)
	TDRD7	Tudor domain containing 7. (1098 aa)
	RIPPLY1	Ripply transcriptional repressor 1. (151 aa)
	C2BH2orf66	Chromosome 2B C2orf66 homolog. (117 aa)
	RIPPLY2	Ripply transcriptional repressor 2. (128 aa)
	OOEP	Oocyte expressed protein. (149 aa)
	RIPPLY3	RIPPLY3 isoform 3. (189 aa)
	LHX1	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
	CXXC4	CXXC4 isoform 2. (366 aa)
	NOTO	Notochord homeobox. (251 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (733 aa)
	OOEP-2	Oocyte expressed protein. (149 aa)
	ENSPTRP00000062011	annotation not available (389 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1386 aa)
	C2CD3	C2CD3 isoform 3. (2298 aa)
	WNT7A	Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
	TDRKH	Tudor and KH domain containing. (605 aa)
	ZIC3	Zic family member 3. (466 aa)
	MEIS1	MEIS1 isoform 7. (465 aa)
	PLD6	Phospholipase D family member 6. (252 aa)
	BASP1	Brain abundant, membrane attached signal protein 1. (226 aa)
	MEIS3	MEIS3 isoform 5. (463 aa)
	TIFAB	TIFAB isoform 1. (161 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	KDM6A	KDM6A isoform 1. (1453 aa)
	MTHFSD	Methenyltetrahydrofolate synthetase domain containing. (383 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BASP1	WT1	ENSPTRP00000067678	ENSPTRP00000087673	Brain abundant, membrane attached signal protein 1.	WT1 transcription factor.	0.615
BMP7	CTNNB1	ENSPTRP00000023489	ENSPTRP00000044466	Bone morphogenetic protein 7.	Catenin (Cadherin-associated protein), beta 1, 88kDa.	0.592
BMP7	FGF10	ENSPTRP00000023489	ENSPTRP00000083399	Bone morphogenetic protein 7.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.505
BMP7	FGFR2	ENSPTRP00000023489	ENSPTRP00000005308	Bone morphogenetic protein 7.	Fibroblast growth factor receptor.	0.499
BMP7	SHH	ENSPTRP00000023489	ENSPTRP00000075730	Bone morphogenetic protein 7.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.648
BMP7	SMAD1	ENSPTRP00000023489	ENSPTRP00000028297	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.792
BMP7	SMAD2	ENSPTRP00000023489	ENSPTRP00000062376	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.770
BMP7	SMAD3	ENSPTRP00000023489	ENSPTRP00000090625	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.704
BMP7	SMAD4	ENSPTRP00000023489	ENSPTRP00000017047	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.699
BMP7	SMAD5	ENSPTRP00000023489	ENSPTRP00000080233	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.788
BMP7	SMAD6	ENSPTRP00000023489	ENSPTRP00000012318	Bone morphogenetic protein 7.	Mothers against decapentaplegic homolog.	0.816
COBL	SIM2	ENSPTRP00000082787	ENSPTRP00000090727	Cordon-bleu WH2 repeat protein.	SIM bHLH transcription factor 2.	0.637
CTNNB1	BMP7	ENSPTRP00000044466	ENSPTRP00000023489	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Bone morphogenetic protein 7.	0.592
CTNNB1	CXXC4	ENSPTRP00000044466	ENSPTRP00000055473	Catenin (Cadherin-associated protein), beta 1, 88kDa.	CXXC4 isoform 2.	0.405
CTNNB1	DLL1	ENSPTRP00000044466	ENSPTRP00000032142	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.535
CTNNB1	EFNB1	ENSPTRP00000044466	ENSPTRP00000090138	Catenin (Cadherin-associated protein), beta 1, 88kDa.	EFNB1 isoform 1; Belongs to the ephrin family.	0.488
CTNNB1	ERBB4	ENSPTRP00000044466	ENSPTRP00000063299	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Receptor protein-tyrosine kinase.	0.608
CTNNB1	FGF10	ENSPTRP00000044466	ENSPTRP00000083399	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.512
CTNNB1	FGFR2	ENSPTRP00000044466	ENSPTRP00000005308	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Fibroblast growth factor receptor.	0.616
CTNNB1	FZD5	ENSPTRP00000044466	ENSPTRP00000021982	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.656