24 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IGFBP2	Insulin-like growth factor binding protein 2, 36kDa. (325 aa)
	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (232 aa)
	IMPA2	Inositol-1-monophosphatase. (288 aa)
	SLC13A5	Sodium-dependent citrate transporter. (568 aa)
	CDH1	CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
	CDKN1B	Cyclin-dependent kinase inhibitor 1B (P27, Kip1). (198 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	ADCY1-2	Adenylate cyclase 1. (1119 aa)
	NFE2L2	Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	PKLR	Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
	MYOG	MYOG isoform 1. (249 aa)
	LIG4	DNA ligase. (911 aa)
	FABP4	Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	PTK2B	PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
	EIF2B5	Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (428 aa)
	GSK3A	Glycogen synthase kinase 3 alpha. (483 aa)
	CALR	Calreticulin. (414 aa)
	NFATC4	Nuclear factor of activated T cells 4. (933 aa)
	TPH2	Tryptophan hydroxylase 2. (490 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY7	ENSPTRP00000032741	ENSPTRP00000062799	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.521
ADCY1	PKLR	ENSPTRP00000032741	ENSPTRP00000056053	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.655
ADCY1-2	ADCY7	ENSPTRP00000065256	ENSPTRP00000062799	Adenylate cyclase 1.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.521
ADCY7	ADCY1	ENSPTRP00000062799	ENSPTRP00000032741	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.521
ADCY7	ADCY1-2	ENSPTRP00000062799	ENSPTRP00000065256	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 1.	0.521
ADCY7	PKLR	ENSPTRP00000062799	ENSPTRP00000056053	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.655
ARL13B	SHH	ENSPTRP00000026120	ENSPTRP00000075730	ADP ribosylation factor like GTPase 13B.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.612
ASCL1	SHH	ENSPTRP00000077846	ENSPTRP00000075730	Achaete-scute family bHLH transcription factor 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.538
CDH1	PTGS2	ENSPTRP00000014119	ENSPTRP00000002990	CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase).	0.479
CDH1	SHH	ENSPTRP00000014119	ENSPTRP00000075730	CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.464
CDKN1B	GSK3A	ENSPTRP00000008044	ENSPTRP00000018979	Cyclin-dependent kinase inhibitor 1B (P27, Kip1).	Glycogen synthase kinase 3 alpha.	0.473
GSK3A	CDKN1B	ENSPTRP00000018979	ENSPTRP00000008044	Glycogen synthase kinase 3 alpha.	Cyclin-dependent kinase inhibitor 1B (P27, Kip1).	0.473
GSK3A	NFE2L2	ENSPTRP00000018979	ENSPTRP00000064585	Glycogen synthase kinase 3 alpha.	Nuclear factor (Erythroid-derived 2)-like 2.	0.681
LIG4	XRCC4	ENSPTRP00000042757	ENSPTRP00000084647	DNA ligase.	X-ray repair complementing defective repair in Chinese hamster cells 4.	0.882
NFE2L2	GSK3A	ENSPTRP00000064585	ENSPTRP00000018979	Nuclear factor (Erythroid-derived 2)-like 2.	Glycogen synthase kinase 3 alpha.	0.681
NFE2L2	PTGS2	ENSPTRP00000064585	ENSPTRP00000002990	Nuclear factor (Erythroid-derived 2)-like 2.	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase).	0.527
PKLR	ADCY1	ENSPTRP00000056053	ENSPTRP00000032741	Pyruvate kinase; Belongs to the pyruvate kinase family.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.655
PKLR	ADCY7	ENSPTRP00000056053	ENSPTRP00000062799	Pyruvate kinase; Belongs to the pyruvate kinase family.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.655
PTGS2	CDH1	ENSPTRP00000002990	ENSPTRP00000014119	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase).	CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins.	0.479
PTGS2	NFE2L2	ENSPTRP00000002990	ENSPTRP00000064585	Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase).	Nuclear factor (Erythroid-derived 2)-like 2.	0.527