STRINGSTRING
IGFBP2 IGFBP2 XRCC4 XRCC4 ASCL1 ASCL1 IMPA2 IMPA2 SLC13A5 SLC13A5 CDH1 CDH1 CDKN1B CDKN1B PTGS2 PTGS2 SHH SHH ADCY1-2 ADCY1-2 NFE2L2 NFE2L2 ADCY7 ADCY7 PKLR PKLR MYOG MYOG LIG4 LIG4 FABP4 FABP4 PTK2B PTK2B ADCY1 ADCY1 EIF2B5 EIF2B5 ARL13B ARL13B GSK3A GSK3A CALR CALR NFATC4 NFATC4 TPH2 TPH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGFBP2Insulin-like growth factor binding protein 2, 36kDa. (325 aa)
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
SLC13A5Sodium-dependent citrate transporter. (568 aa)
CDH1CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B (P27, Kip1). (198 aa)
PTGS2Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
ADCY1-2Adenylate cyclase 1. (1119 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
MYOGMYOG isoform 1. (249 aa)
LIG4DNA ligase. (911 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
EIF2B5Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
GSK3AGlycogen synthase kinase 3 alpha. (483 aa)
CALRCalreticulin. (414 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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