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| | RHOA | Ras homolog family member A. (193 aa) |
| | ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | HRG | Histidine rich glycoprotein. (525 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (234 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | CXCL13 | C-X-C motif chemokine. (109 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (707 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | SEMA5A | SEMA5A isoform 1. (1074 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | SPARC | Secreted protein acidic and cysteine rich. (303 aa) |
| | EDN1 | EDN1 isoform 1. (212 aa) |
| | GPLD1 | GPLD1 isoform 2. (840 aa) |
| | NUS1 | Nuclear undecaprenyl pyrophosphate synthase 1 homolog. (293 aa) |
| | PLG | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (813 aa) |
| | MEOX2 | Mesenchyme homeobox 2. (302 aa) |
| | HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | JCAD | JCAD isoform 2. (1354 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | KRIT1 | KRIT1, ankyrin repeat containing. (736 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa) |
| | ANGPT2 | ANGPT2 isoform 1. (496 aa) |
| | STC1 | Stanniocalcin 1. (247 aa) |
| | PTK2B | PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | ADGRA2 | G protein-coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1338 aa) |
| | TSTA3 | Tissue specific transplantation antigen P35B. (321 aa) |
| | KLF4 | Kruppel-like factor 4 (Gut). (479 aa) |
| | NOTCH1 | NOTCH1 isoform 1. (2555 aa) |
| | AMOT | AMOT isoform 2. (1094 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa) |
| | TMSB4X | Thymosin beta 4 X-linked. (44 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | ADAM17 | ADAM17 isoform 3. (999 aa) |
| | GADD45A | Growth arrest and DNA-damage-inducible, alpha. (165 aa) |
| | FOXC2 | Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa) |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) |
| | DAB2IP | DAB2 interacting protein. (1189 aa) |
| | LOC741304 | Dehydrodolichyl diphosphate synthase complex subunit NUS1. (278 aa) |
| | ENSPTRP00000061486 | Dual specificity mitogen-activated protein kinase kinase 3 isoform X1. (178 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | TBXA2R | Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa) |
| | LOC107970066 | LOW QUALITY PROTEIN: putative high mobility group protein B1-like 1. (198 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | CK820_G0054728 | MECP2 isoform 14. (493 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (478 aa) |
| | KRIT1-2 | KRIT1 ankyrin repeat containing. (736 aa) |
| | NFE2L2 | Nuclear factor (Erythroid-derived 2)-like 2. (605 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ATP5F1A | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (576 aa) |
| | WNT7A | Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (854 aa) |
| | RHOB | Ras homolog gene family, member B. (286 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (323 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa) |
| | CD40 | CD40 molecule, TNF receptor superfamily member 5. (277 aa) |
| | ITGB3 | Integrin beta-3 isoform X2. (837 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa) |
| | SEMA4A | SEMA4A isoform 10; Belongs to the semaphorin family. (761 aa) |
| | GDF2 | GDF2 isoform 1. (429 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | ENSPTRP00000069497 | annotation not available (53 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (696 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (950 aa) |
| | RIN2 | Ras and Rab interactor 2. (944 aa) |
| | ENSPTRP00000072328 | annotation not available (210 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | NR2E1 | Nuclear receptor subfamily 2 group E member 1. (422 aa) |
| | ENSPTRP00000073361 | annotation not available (388 aa) |
| | HMGB1 | HMGB1 isoform 1. (215 aa) |
| | ENSPTRP00000075003 | annotation not available (254 aa) |
| | FOXP1 | FOXP1 isoform 2. (693 aa) |
| | ENSPTRP00000075697 | annotation not available (207 aa) |
| | ENSPTRP00000076371 | annotation not available (194 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa) |
| | ENSPTRP00000076822 | annotation not available (142 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | ADGRB1 | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1612 aa) |
| | PLPP3 | T0036865 isoform 1. (342 aa) |
| | NR2F2 | Nuclear receptor subfamily 2, group F, member 2. (414 aa) |
| | SCARB1 | SCARB1 isoform 8; Belongs to the CD36 family. (552 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | PATZ1 | POZ (BTB) and AT hook containing zinc finger 1. (687 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | ANGPT4 | ANGPT4 isoform 1. (503 aa) |
| | SP100 | Nuclear autoantigen Sp-100. (885 aa) |
| | AAMP | Angio associated migratory cell protein. (435 aa) |
| | NRP2 | Neuropilin; Belongs to the neuropilin family. (931 aa) |
| | ZNF580 | Zinc finger protein 580. (172 aa) |
| | RRAS | Related RAS viral (R-ras) oncogene homolog. (218 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | CEACAM1 | CEACAM1 isoform 3. (518 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | CALR | Calreticulin. (414 aa) |
| | BSG | BSG isoform 8. (383 aa) |
| | CCBE1 | Collagen and calcium binding EGF domains 1. (406 aa) |
| | PTPRM | PTPRM isoform 4. (1465 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | APOH | Beta-2-glycoprotein 1; Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. (345 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) |
| | GRN | Granulin precursor. (593 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa) |
| | STAT5A | Signal transducer and activator of transcription. (783 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | NF1 | Neurofibromin 1. (2839 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | SERPINF1 | SERPINF1 isoform 1; Belongs to the serpin family. (418 aa) |
| | CIB1 | Calcium and integrin binding 1. (231 aa) |
| | DNAJA4 | DnaJ heat shock protein family (Hsp40) member A4. (426 aa) |
| | MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) |
| | SPRED1 | Sprouty-related, EVH1 domain containing 1. (444 aa) |
| | LGMN | LGMN isoform 1. (433 aa) |
| | SYNJ2BP | Synaptojanin 2 binding protein. (145 aa) |
| | RHOJ | Ras homolog gene family, member J. (214 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (873 aa) |
| | RGCC | Chromosome 13 open reading frame 15. (137 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (359 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa) |
| | MMRN2 | MMRN2 isoform 1. (949 aa) |
| | SIRT1 | SIRT1 isoform 2. (751 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | EFNA1 | EFNA1 isoform 2; Belongs to the ephrin family. (205 aa) |
| | TMSB4X-2 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa) |
| | EPHA2 | EPH receptor A2. (976 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | SVBP | Coiled-coil domain containing 23. (66 aa) |
| | SIRT1-2 | Sirtuin 1. (751 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | ANGPT1 | ANGPT1 isoform 2. (498 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | NR2E1-2 | Nuclear receptor subfamily 2 group E member 1. (385 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and the formation of lipid rafts bearing GPI-anchor proteins. Regulates surface expression of MHC1 and ICAM1 proteins increasing susceptibility to T- cell mediated cytotoxicity. R [...] (167 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase-1. (542 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1251 aa) |
| | GPI | Glucose-6-phosphate isomerase; Belongs to the GPI family. (597 aa) |
| | HDAC7 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1016 aa) |
| | ENSPTRP00000088702 | annotation not available (170 aa) |
| | LOC473221 | Glutamine synthetase pseudogene. (351 aa) |
| | ENSPTRP00000087735 | annotation not available (204 aa) |
| | ENSPTRP00000087640 | annotation not available (475 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | VASH1 | VASH1 isoform 1. (365 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | SP100-2 | Nuclear autoantigen Sp-100; Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regul [...] (187 aa) |
| | CARD10 | Caspase recruitment domain family member 10. (1032 aa) |
| | EMC10 | ER membrane protein complex subunit 10. (371 aa) |
| | PRCP | Prolylcarboxypeptidase. (517 aa) |
| | RAC1-2 | Rac family small GTPase 1. (212 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (398 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa) |
| | CK820_G0053450-2 | MAP2K3 isoform 2. (298 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (200 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (366 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) |
| | STARD13 | StAR-related lipid transfer (START) domain containing 13. (1113 aa) |
| | SRPX2 | Sushi-repeat containing protein, X-linked 2. (469 aa) |
| | BMP4-2 | Bone morphogenetic protein 4. (408 aa) |
| | PTN | PTN isoform 2. (172 aa) |
| | SLIT2 | Slit guidance ligand 2. (1542 aa) |
