31 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ERRFI1	ERBB receptor feedback inhibitor 1. (462 aa)
	TNFRSF1B	Tumor necrosis factor receptor superfamily, member 1B. (461 aa)
	LMNA	LMNA isoform 8; Belongs to the intermediate filament family. (664 aa)
	RGS4	Regulator of G protein signaling 4. (302 aa)
	RGS2	Regulator of G-protein signaling 2, 24kDa. (211 aa)
	P2RX4	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa)
	FOXO1	FOXO1 isoform 1. (655 aa)
	YY1	YY1 transcription factor. (414 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	CTDP1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (961 aa)
	GSK3A	Glycogen synthase kinase 3 alpha. (483 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha. (467 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	TOMM70	Translocase of outer mitochondrial membrane 70 homolog A. (608 aa)
	PI16	PI16 isoform 1; Belongs to the CRISP family. (465 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	G6PD	Glucose-6-phosphate dehydrogenase. (560 aa)
	TNFRSF1A	Tumor necrosis factor receptor superfamily, member 1A. (455 aa)
	JARID2	Jumonji and AT-rich interaction domain containing 2. (1246 aa)
	TRIM63	Tripartite motif containing 63. (379 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
	GATA5	GATA binding protein 5. (397 aa)
	FOXP1	FOXP1 isoform 2. (693 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	GLRX3	GLRX3 isoform 1. (335 aa)
	ENSPTRP00000084510	annotation not available (456 aa)
	ENSPTRP00000084909	annotation not available (278 aa)
	MLIP	Muscular LMNA interacting protein. (993 aa)
	ENSPTRP00000089297	annotation not available (265 aa)
	SMAD3	Mothers against decapentaplegic homolog. (442 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP2B4	G6PD	ENSPTRP00000069379	ENSPTRP00000038687	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Glucose-6-phosphate dehydrogenase.	0.568
BMP10	SMAD4	ENSPTRP00000078228	ENSPTRP00000017047	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.455
CAV3	LMNA	ENSPTRP00000025136	ENSPTRP00000002448	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	LMNA isoform 8; Belongs to the intermediate filament family.	0.476
ENSPTRP00000089297	PPARA	ENSPTRP00000089297	ENSPTRP00000025003	annotation not available	Peroxisome proliferator-activated receptor alpha.	0.434
ENSPTRP00000089297	PPARG	ENSPTRP00000089297	ENSPTRP00000076701	annotation not available	Peroxisome proliferator-activated receptor gamma isoform X2.	0.586
ENSPTRP00000089297	SMAD3	ENSPTRP00000089297	ENSPTRP00000090625	annotation not available	Mothers against decapentaplegic homolog.	0.730
ENSPTRP00000089297	SMAD4	ENSPTRP00000089297	ENSPTRP00000017047	annotation not available	Mothers against decapentaplegic homolog.	0.690
ENSPTRP00000089297	TRIM63	ENSPTRP00000089297	ENSPTRP00000068590	annotation not available	Tripartite motif containing 63.	0.721
FOXO1	PPARA	ENSPTRP00000009886	ENSPTRP00000025003	FOXO1 isoform 1.	Peroxisome proliferator-activated receptor alpha.	0.434
FOXO1	PPARG	ENSPTRP00000009886	ENSPTRP00000076701	FOXO1 isoform 1.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.586
FOXO1	SMAD3	ENSPTRP00000009886	ENSPTRP00000090625	FOXO1 isoform 1.	Mothers against decapentaplegic homolog.	0.730
FOXO1	SMAD4	ENSPTRP00000009886	ENSPTRP00000017047	FOXO1 isoform 1.	Mothers against decapentaplegic homolog.	0.690
FOXO1	TRIM63	ENSPTRP00000009886	ENSPTRP00000068590	FOXO1 isoform 1.	Tripartite motif containing 63.	0.721
G6PD	ATP2B4	ENSPTRP00000038687	ENSPTRP00000069379	Glucose-6-phosphate dehydrogenase.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.568
GSK3A	RGS2	ENSPTRP00000018979	ENSPTRP00000002995	Glycogen synthase kinase 3 alpha.	Regulator of G-protein signaling 2, 24kDa.	0.461
GSK3A	RGS4	ENSPTRP00000018979	ENSPTRP00000002692	Glycogen synthase kinase 3 alpha.	Regulator of G protein signaling 4.	0.461
GSK3A	SMAD3	ENSPTRP00000018979	ENSPTRP00000090625	Glycogen synthase kinase 3 alpha.	Mothers against decapentaplegic homolog.	0.509
JARID2	YY1	ENSPTRP00000068115	ENSPTRP00000011451	Jumonji and AT-rich interaction domain containing 2.	YY1 transcription factor.	0.556
LMNA	CAV3	ENSPTRP00000002448	ENSPTRP00000025136	LMNA isoform 8; Belongs to the intermediate filament family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.476
LMNA	MLIP	ENSPTRP00000002448	ENSPTRP00000088327	LMNA isoform 8; Belongs to the intermediate filament family.	Muscular LMNA interacting protein.	0.417