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| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | FGFBP1 | Fibroblast growth factor binding protein 1. (234 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | HYAL1 | Hyaluronidase. (435 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa) |
| | CAPN7 | CAPN7 isoform 3; Belongs to the peptidase C2 family. (813 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | HMOX1 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (311 aa) |
| | PPM1F | PPM1F isoform 4. (454 aa) |
| | MMP9 | Matrix metallopeptidase 9. (699 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | ANGPT4 | ANGPT4 isoform 1. (503 aa) |
| | VIL1 | VIL1 isoform 1. (827 aa) |
| | AAMP | Angio associated migratory cell protein. (435 aa) |
| | NRP2 | Neuropilin; Belongs to the neuropilin family. (931 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | ZNF580 | Zinc finger protein 580. (172 aa) |
| | RRAS | Related RAS viral (R-ras) oncogene homolog. (218 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | CALR | Calreticulin. (414 aa) |
| | BSG | BSG isoform 8. (383 aa) |
| | CCBE1 | Collagen and calcium binding EGF domains 1. (406 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) |
| | ITGA3 | ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa) |
| | GRN | Granulin precursor. (593 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (323 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. (288 aa) |
| | CD40 | CD40 molecule, TNF receptor superfamily member 5. (277 aa) |
| | ITGB3 | Integrin beta-3 isoform X2. (837 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | DOCK5 | Dedicator of cytokinesis 5; Belongs to the DOCK family. (1881 aa) |
| | ENSPTRP00000069497 | annotation not available (53 aa) |
| | ARF6 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | ENSPTRP00000070303 | annotation not available (117 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (950 aa) |
| | RIN2 | Ras and Rab interactor 2. (944 aa) |
| | CLASP1 | Cytoplasmic linker associated protein 1. (1549 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | ENSPTRP00000073361 | annotation not available (388 aa) |
| | ENSPTRP00000075003 | annotation not available (254 aa) |
| | FOXP1 | FOXP1 isoform 2. (693 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa) |
| | ENSPTRP00000076371 | annotation not available (194 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | CIB1 | Calcium and integrin binding 1. (231 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (140 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | STAT5A | Signal transducer and activator of transcription. (783 aa) |
| | ENSPTRP00000087640 | annotation not available (475 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | RREB1 | Ras responsive element binding protein 1. (1742 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | EMC10 | ER membrane protein complex subunit 10. (371 aa) |
| | ENSPTRP00000085241 | annotation not available (93 aa) |
| | RAC1-2 | Rac family small GTPase 1. (212 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (398 aa) |
| | ENSPTRP00000083809 | annotation not available (152 aa) |
| | CK820_G0053450-2 | MAP2K3 isoform 2. (298 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (200 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | ITGA2 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa) |
| | ENSPTRP00000081955 | annotation not available (66 aa) |
| | FUT1 | Galactoside 2-alpha-L-fucosyltransferase 1; Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Gal-beta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. Belongs to the glycosyltransferase 11 family. (366 aa) |
| | SRPX2 | Sushi-repeat containing protein, X-linked 2. (469 aa) |
| | RAB11A | RAB11A, member RAS oncogene family. (216 aa) |
| | BMP4-2 | Bone morphogenetic protein 4. (408 aa) |
| | MAPRE2 | Microtubule-associated protein, RP/EB family, member 2. (327 aa) |
| | MAP4K4 | MAP4K4 isoform 6. (1347 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | SEMA5A | SEMA5A isoform 1. (1074 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (685 aa) |
| | HBEGF | Heparin-binding EGF-like growth factor. (208 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | SPARC | Secreted protein acidic and cysteine rich. (303 aa) |
| | EDN1 | EDN1 isoform 1. (212 aa) |
| | GPLD1 | GPLD1 isoform 2. (840 aa) |
| | NUS1 | Nuclear undecaprenyl pyrophosphate synthase 1 homolog. (293 aa) |
| | PLG | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (813 aa) |
| | HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) |
| | JCAD | JCAD isoform 2. (1354 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa) |
| | PTK2B | PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | ADGRA2 | G protein-coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1338 aa) |
| | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa) |
| | CTSH | CTSH isoform 11; Belongs to the peptidase C1 family. (335 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | LGMN | LGMN isoform 1. (433 aa) |
| | RHOJ | Ras homolog gene family, member J. (214 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (873 aa) |
| | IRS2 | IRS2 isoform 1. (1340 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa) |
| | DOCK1 | DOCK1 isoform 1; Belongs to the DOCK family. (1854 aa) |
| | SIRT1 | SIRT1 isoform 2. (751 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa) |
| | TMSB4X-2 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TSTA3 | Tissue specific transplantation antigen P35B. (321 aa) |
| | EPB41L4B | EPB41L4B isoform 2. (938 aa) |
| | HDAC6 | Histone deacetylase 6. (146 aa) |
| | AMOT | AMOT isoform 2. (1094 aa) |
| | RAB25 | RAB25, member RAS oncogene family. (213 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa) |
| | GAB2 | GRB2-associated-binding protein 2. (676 aa) |
| | TMSB4X | Thymosin beta 4 X-linked. (44 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | ADAM17 | ADAM17 isoform 3. (999 aa) |
| | FOXC2 | Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa) |
| | GATA2 | GATA binding protein 2. (480 aa) |
| | RTN4 | Reticulon. (1192 aa) |
| | HAS2 | Hyaluronan synthase 2. (554 aa) |
| | LOC741304 | Dehydrodolichyl diphosphate synthase complex subunit NUS1. (278 aa) |
| | ENSPTRP00000061486 | Dual specificity mitogen-activated protein kinase kinase 3 isoform X1. (178 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (733 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | NFE2L2 | Nuclear factor (Erythroid-derived 2)-like 2. (605 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ATP5F1A | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (576 aa) |
| | CLASP2 | CLASP2 isoform 3. (1522 aa) |
| | WNT7A | Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa) |
| | IQSEC1 | IQ motif and Sec7 domain 1. (1114 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (854 aa) |
| | RHOB | Ras homolog gene family, member B. (286 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | LOC452254 | LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 1-like. (863 aa) |
| | ENSPTRP00000088582 | annotation not available (66 aa) |
| | ENSPTRP00000088702 | annotation not available (170 aa) |
| | HDAC7 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1016 aa) |
| | GPI | Glucose-6-phosphate isomerase; Belongs to the GPI family. (597 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1251 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase-1. (542 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | ANGPT1 | ANGPT1 isoform 2. (498 aa) |
| | GLIPR2 | GLIPR2 isoform 2; Belongs to the CRISP family. (165 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | SIRT1-2 | Sirtuin 1. (751 aa) |
| | ENSPTRP00000076822 | annotation not available (142 aa) |
| | PLPP3 | T0036865 isoform 1. (342 aa) |
| | SCARB1 | SCARB1 isoform 8; Belongs to the CD36 family. (552 aa) |
