19 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASPH	ASPH isoform 1. (762 aa)
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
	ANK3	ANK3 isoform 5. (4377 aa)
	IRX3	Iroquois homeobox 3. (500 aa)
	CALM3	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
	HRC	HRC isoform 2. (693 aa)
	CAV1	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
	TRDN	TRDN isoform 1. (730 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	PDE4D	Phosphodiesterase. (809 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	SRI	SRI isoform 1. (205 aa)
	SRI-2	SRI isoform 5. (237 aa)
	CALM1	CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
	ENSPTRP00000085680	annotation not available (88 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (446 aa)
	ENSPTRP00000090392	annotation not available (93 aa)
	CK820_G0029100	SRI isoform 2. (98 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANK3	CALM3	ENSPTRP00000004348	ENSPTRP00000019197	ANK3 isoform 5.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.646
ASPH	CALM3	ENSPTRP00000053155	ENSPTRP00000019197	ASPH isoform 1.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.551
ASPH	CASQ2	ENSPTRP00000053155	ENSPTRP00000001966	ASPH isoform 1.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.982
ASPH	TRDN	ENSPTRP00000053155	ENSPTRP00000058505	ASPH isoform 1.	TRDN isoform 1.	0.998
CALM1	CALM3	ENSPTRP00000082789	ENSPTRP00000019197	CALM1 isoform 3; Belongs to the calmodulin family.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.772
CALM1	CAMK2D	ENSPTRP00000082789	ENSPTRP00000088560	CALM1 isoform 3; Belongs to the calmodulin family.	Calcium/calmodulin dependent protein kinase II delta.	0.887
CALM1	CASQ2	ENSPTRP00000082789	ENSPTRP00000001966	CALM1 isoform 3; Belongs to the calmodulin family.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.507
CALM1	TRDN	ENSPTRP00000082789	ENSPTRP00000058505	CALM1 isoform 3; Belongs to the calmodulin family.	TRDN isoform 1.	0.464
CALM3	ANK3	ENSPTRP00000019197	ENSPTRP00000004348	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	ANK3 isoform 5.	0.646
CALM3	ASPH	ENSPTRP00000019197	ENSPTRP00000053155	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	ASPH isoform 1.	0.551
CALM3	CALM1	ENSPTRP00000019197	ENSPTRP00000082789	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	CALM1 isoform 3; Belongs to the calmodulin family.	0.772
CALM3	CAMK2D	ENSPTRP00000019197	ENSPTRP00000088560	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Calcium/calmodulin dependent protein kinase II delta.	0.926
CALM3	CASQ2	ENSPTRP00000019197	ENSPTRP00000001966	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.511
CALM3	CAV1	ENSPTRP00000019197	ENSPTRP00000033587	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...]	0.868
CALM3	ENSPTRP00000090392	ENSPTRP00000019197	ENSPTRP00000090392	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	annotation not available	0.773
CALM3	SRI	ENSPTRP00000019197	ENSPTRP00000080641	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	SRI isoform 1.	0.522
CALM3	SRI-2	ENSPTRP00000019197	ENSPTRP00000081612	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	SRI isoform 5.	0.522
CALM3	TRDN	ENSPTRP00000019197	ENSPTRP00000058505	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	TRDN isoform 1.	0.703
CAMK2D	CALM1	ENSPTRP00000088560	ENSPTRP00000082789	Calcium/calmodulin dependent protein kinase II delta.	CALM1 isoform 3; Belongs to the calmodulin family.	0.887
CAMK2D	CALM3	ENSPTRP00000088560	ENSPTRP00000019197	Calcium/calmodulin dependent protein kinase II delta.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.926