STRINGSTRING
PLPP7 PLPP7 RBM38 RBM38 CK820_G0048817 CK820_G0048817 LMOD3 LMOD3 SHOX2 SHOX2 BCL2 BCL2 ATP11A ATP11A ACTN3 ACTN3 ENSPTRP00000084090 ENSPTRP00000084090 CYP26B1 CYP26B1 HDAC4 HDAC4 TMEM119 TMEM119 BHLHA15-2 BHLHA15-2 DMPK DMPK XBP1 XBP1 CK820_G0046635 CK820_G0046635 MAML1 MAML1 NIBAN2 NIBAN2 MYOG MYOG MAMSTR MAMSTR NOTCH1 NOTCH1 CCN3 CCN3 BHLHA15 BHLHA15 HDAC9 HDAC9 MAPK14 MAPK14 NKX2-5 NKX2-5 NLN NLN MTOR MTOR MYOD1 MYOD1 BHLHE41 BHLHE41 MYF6 MYF6 MYF5 MYF5 MMP14 MMP14 FBXO22 FBXO22 TRIM72 TRIM72 PIEZO1 PIEZO1 MYOCD MYOCD HDAC5 HDAC5 SMYD1 SMYD1 RBM24 RBM24 TBX1 TBX1 CAV3 CAV3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLPP7Phosphatidic acid phosphatase type 2 domain containing 3. (271 aa)
RBM38RNA binding motif protein 38. (207 aa)
CK820_G0048817RBM38 isoform 2. (182 aa)
LMOD3LMOD3 isoform 1. (560 aa)
SHOX2SHOX2 isoform 2. (343 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
ENSPTRP00000084090annotation not available (121 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
TMEM119Transmembrane protein 119. (283 aa)
BHLHA15-2Basic helix-loop-helix family member a15. (189 aa)
DMPKDystrophia myotonica-protein kinase. (639 aa)
XBP1XBP1 isoform 4. (381 aa)
CK820_G0046635NACA isoform 1. (1839 aa)
MAML1MAML1 isoform 1. (1016 aa)
NIBAN2FAM129B isoform 2. (746 aa)
MYOGMYOG isoform 1. (249 aa)
MAMSTRMAMSTR isoform 1. (312 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
CCN3NOV isoform 1. (357 aa)
BHLHA15Basic helix-loop-helix family member a15. (189 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
NLNNeurolysin (Metallopeptidase M3 family). (704 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
BHLHE41Basic helix-loop-helix family member e41. (482 aa)
MYF6Myogenic factor 6. (242 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
FBXO22F-box protein 22. (403 aa)
TRIM72Tripartite motif containing 72. (477 aa)
PIEZO1Piezo-type mechanosensitive ion channel component. (2516 aa)
MYOCDMYOCD isoform 2. (986 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
RBM24RNA binding motif protein 24. (254 aa)
TBX1TBX1 isoform 1. (478 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (32%) [HD]