STRINGSTRING
GSTO1 GSTO1 CASQ2 CASQ2 CACNA1C CACNA1C PRKACA PRKACA TMEM38A TMEM38A CALM3 CALM3 HRC HRC FKBP1B FKBP1B ANK2 ANK2 CLIC2 CLIC2 ASPH ASPH ENSPTRP00000061732 ENSPTRP00000061732 SLC8A1 SLC8A1 RYR2 RYR2 CLIC2-2 CLIC2-2 DMD DMD PLN PLN ATP1A2 ATP1A2 ENSPTRP00000082718 ENSPTRP00000082718 CALM1 CALM1 DMD-2 DMD-2 TMEM38B TMEM38B CAMK2D CAMK2D ENSPTRP00000090392 ENSPTRP00000090392
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSTO1Glutathione S-transferase omega 1. (241 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
TMEM38ATransmembrane protein 38A. (299 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
HRCHRC isoform 2. (693 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
ANK2ANK2 isoform 1. (3957 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
ASPHASPH isoform 1. (762 aa)
ENSPTRP00000061732annotation not available (285 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
RYR2RYR2 isoform 1. (4941 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
DMDDMD isoform 3. (3685 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ENSPTRP00000082718annotation not available (235 aa)
CALM1CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
DMD-2Dystrophin. (643 aa)
TMEM38BTransmembrane protein 38B. (297 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
ENSPTRP00000090392annotation not available (93 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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