STRINGSTRING
NKX6-2 NKX6-2 MYRF MYRF ACY3 ACY3 TENM4 TENM4 EIF2B1 EIF2B1 EIF2B2 EIF2B2 FA2H FA2H ASPA ASPA B4GALT6 B4GALT6 TGFB1 TGFB1 EIF2B4 EIF2B4 MAL MAL NKX2-2 NKX2-2 B4GALT5 B4GALT5 EIF2B5 EIF2B5 NSUN5 NSUN5 CLU CLU PLP1 PLP1 WASF3 WASF3 HES5 HES5 SOX10 SOX10 LYN LYN CD22-2 CD22-2 CNTNAP1 CNTNAP1 OLIG1 OLIG1 LPAR1 LPAR1 EIF2B3 EIF2B3 PRDM8 PRDM8 ID4 ID4 ABCA2 ABCA2 NSUN5-2 NSUN5-2 CNTN1 CNTN1 SHH SHH LOC100611979 LOC100611979 ASCL1 ASCL1 ERCC2 ERCC2 OLIG1-2 OLIG1-2 HES5-2 HES5-2 HDAC11 HDAC11 MED12 MED12 CNTN2 CNTN2 ENSPTRP00000089750 ENSPTRP00000089750 PTEN PTEN SOX11 SOX11 TPPP TPPP ENSPTRP00000093022 ENSPTRP00000093022 NCSTN NCSTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX6-2NKX6-2 isoform 1. (276 aa)
MYRFMYRF isoform 2. (932 aa)
ACY3Aspartoacylase (Aminocyclase) 3. (319 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
EIF2B1Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (306 aa)
EIF2B2Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ASPAAspartoacylase (Canavan disease). (313 aa)
B4GALT6UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6. (382 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
EIF2B4Eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
MALMal, T cell differentiation protein. (153 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
B4GALT5UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5. (388 aa)
EIF2B5Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa)
NSUN5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (470 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
PLP1Proteolipid protein 1. (277 aa)
WASF3WH2 domain-containing protein. (502 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
SOX10SRY-box transcription factor 10. (466 aa)
LYNTyrosine-protein kinase. (512 aa)
CD22-2B-cell receptor CD22. (626 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
OLIG1OLIG1 isoform 2. (272 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
EIF2B3Eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa. (452 aa)
PRDM8PR domain containing 8. (1065 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
ABCA2ABCA2 isoform 8. (2364 aa)
NSUN5-2NOP2/Sun domain family, member 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (466 aa)
CNTN1CNTN1 isoform 1. (1028 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
LOC100611979Probable 28S rRNA (cytosine-C(5))-methyltransferase. (448 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
OLIG1-2OLIG1 isoform 1. (272 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
HDAC11HDAC11 isoform 14. (374 aa)
MED12Mediator of RNA polymerase II transcription subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifi [...] (2182 aa)
CNTN2CNTN2 isoform 13. (1040 aa)
ENSPTRP00000089750annotation not available (448 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
SOX11Transcription factor SOX. (441 aa)
TPPPTubulin polymerization promoting protein. (219 aa)
ENSPTRP00000093022annotation not available (563 aa)
NCSTNNCSTN isoform 1. (721 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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