11 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JPH1	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
	AKAP6	A-kinase anchoring protein 6. (2319 aa)
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
	RYR1	RYR1 isoform 3. (5037 aa)
	CK820_G0030361	RYR1 isoform 5. (4901 aa)
	RYR2	RYR2 isoform 1. (4941 aa)
	JPH2	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
	JPH4	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
	TRDN	TRDN isoform 1. (730 aa)
	JPH3	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
	ASPH	ASPH isoform 1. (762 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP6	RYR2	ENSPTRP00000010600	ENSPTRP00000064508	A-kinase anchoring protein 6.	RYR2 isoform 1.	0.853
ASPH	CASQ2	ENSPTRP00000053155	ENSPTRP00000001966	ASPH isoform 1.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.982
ASPH	CK820_G0030361	ENSPTRP00000053155	ENSPTRP00000090805	ASPH isoform 1.	RYR1 isoform 5.	0.670
ASPH	JPH1	ENSPTRP00000053155	ENSPTRP00000053135	ASPH isoform 1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.669
ASPH	JPH2	ENSPTRP00000053155	ENSPTRP00000062417	ASPH isoform 1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.589
ASPH	JPH3	ENSPTRP00000053155	ENSPTRP00000053372	ASPH isoform 1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.570
ASPH	JPH4	ENSPTRP00000053155	ENSPTRP00000059066	ASPH isoform 1.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.604
ASPH	RYR1	ENSPTRP00000053155	ENSPTRP00000092559	ASPH isoform 1.	RYR1 isoform 3.	0.931
ASPH	RYR2	ENSPTRP00000053155	ENSPTRP00000064508	ASPH isoform 1.	RYR2 isoform 1.	0.979
ASPH	TRDN	ENSPTRP00000053155	ENSPTRP00000058505	ASPH isoform 1.	TRDN isoform 1.	0.998
CASQ2	ASPH	ENSPTRP00000001966	ENSPTRP00000053155	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	ASPH isoform 1.	0.982
CASQ2	JPH2	ENSPTRP00000001966	ENSPTRP00000062417	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.543
CASQ2	RYR1	ENSPTRP00000001966	ENSPTRP00000092559	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	RYR1 isoform 3.	0.959
CASQ2	RYR2	ENSPTRP00000001966	ENSPTRP00000064508	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	RYR2 isoform 1.	0.991
CASQ2	TRDN	ENSPTRP00000001966	ENSPTRP00000058505	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	TRDN isoform 1.	0.994
CK820_G0030361	ASPH	ENSPTRP00000090805	ENSPTRP00000053155	RYR1 isoform 5.	ASPH isoform 1.	0.670
CK820_G0030361	JPH1	ENSPTRP00000090805	ENSPTRP00000053135	RYR1 isoform 5.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.688
CK820_G0030361	JPH2	ENSPTRP00000090805	ENSPTRP00000062417	RYR1 isoform 5.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.520
CK820_G0030361	JPH3	ENSPTRP00000090805	ENSPTRP00000053372	RYR1 isoform 5.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.522
CK820_G0030361	JPH4	ENSPTRP00000090805	ENSPTRP00000059066	RYR1 isoform 5.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.533