(15 nodes) Coenzyme A biosynthetic process network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PANK1	Pantothenate kinase 1. (598 aa)
	CK820_G0035115	ACOT7 isoform 4. (359 aa)
	ENSPTRP00000088376	annotation not available (334 aa)
	PANK4-2	Pantothenate kinase 4. (889 aa)
	COASY	Coenzyme A synthase. (593 aa)
	PPCDC	Phosphopantothenoylcysteine decarboxylase. (221 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
	SLC25A16	Solute carrier family 25 (Mitochondrial carrier Graves disease autoantigen), member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family. (332 aa)
	CCDC30	CCDC30 isoform 12. (783 aa)
	PANK4	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. (781 aa)
	DCAKD	Dephospho-CoA kinase domain containing. (231 aa)
	PANK3	Pantothenate kinase 3. (370 aa)
	PANK2	Pantothenate kinase 2. (570 aa)
	PPCS	Phosphopantothenoylcysteine synthetase. (311 aa)
	ACOT7	Acyl-CoA thioesterase 7. (482 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC30	COASY	ENSPTRP00000001054	ENSPTRP00000015680	CCDC30 isoform 12.	Coenzyme A synthase.	0.943
CCDC30	DCAKD	ENSPTRP00000001054	ENSPTRP00000015800	CCDC30 isoform 12.	Dephospho-CoA kinase domain containing.	0.523
CCDC30	PANK4	ENSPTRP00000001054	ENSPTRP00000000094	CCDC30 isoform 12.	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.	0.893
CCDC30	PANK4-2	ENSPTRP00000001054	ENSPTRP00000087813	CCDC30 isoform 12.	Pantothenate kinase 4.	0.893
CCDC30	PPCDC	ENSPTRP00000001054	ENSPTRP00000012477	CCDC30 isoform 12.	Phosphopantothenoylcysteine decarboxylase.	0.651
COASY	CCDC30	ENSPTRP00000015680	ENSPTRP00000001054	Coenzyme A synthase.	CCDC30 isoform 12.	0.943
COASY	DCAKD	ENSPTRP00000015680	ENSPTRP00000015800	Coenzyme A synthase.	Dephospho-CoA kinase domain containing.	0.836
COASY	ENSPTRP00000088376	ENSPTRP00000015680	ENSPTRP00000088376	Coenzyme A synthase.	annotation not available	0.425
COASY	PANK1	ENSPTRP00000015680	ENSPTRP00000074007	Coenzyme A synthase.	Pantothenate kinase 1.	0.953
COASY	PANK2	ENSPTRP00000015680	ENSPTRP00000044747	Coenzyme A synthase.	Pantothenate kinase 2.	0.983
COASY	PANK3	ENSPTRP00000015680	ENSPTRP00000029910	Coenzyme A synthase.	Pantothenate kinase 3.	0.940
COASY	PANK4	ENSPTRP00000015680	ENSPTRP00000000094	Coenzyme A synthase.	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.	0.676
COASY	PANK4-2	ENSPTRP00000015680	ENSPTRP00000087813	Coenzyme A synthase.	Pantothenate kinase 4.	0.676
COASY	PPCDC	ENSPTRP00000015680	ENSPTRP00000012477	Coenzyme A synthase.	Phosphopantothenoylcysteine decarboxylase.	0.997
COASY	PPCS	ENSPTRP00000015680	ENSPTRP00000052446	Coenzyme A synthase.	Phosphopantothenoylcysteine synthetase.	0.959
DCAKD	CCDC30	ENSPTRP00000015800	ENSPTRP00000001054	Dephospho-CoA kinase domain containing.	CCDC30 isoform 12.	0.523
DCAKD	COASY	ENSPTRP00000015800	ENSPTRP00000015680	Dephospho-CoA kinase domain containing.	Coenzyme A synthase.	0.836
DCAKD	PANK4	ENSPTRP00000015800	ENSPTRP00000000094	Dephospho-CoA kinase domain containing.	4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.	0.470
DCAKD	PANK4-2	ENSPTRP00000015800	ENSPTRP00000087813	Dephospho-CoA kinase domain containing.	Pantothenate kinase 4.	0.470
DCAKD	PPCDC	ENSPTRP00000015800	ENSPTRP00000012477	Dephospho-CoA kinase domain containing.	Phosphopantothenoylcysteine decarboxylase.	0.626