15 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FYN	Tyrosine-protein kinase. (537 aa)
	PLAA	Phospholipase A2-activating protein. (795 aa)
	ARHGAP6	Rho GTPase activating protein 6. (974 aa)
	BTK	BTK isoform 2. (693 aa)
	APOC4	Apolipoprotein C4. (173 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	CCL3	C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (92 aa)
	ENSPTRP00000072507	annotation not available (659 aa)
	CCL5	C-C motif chemokine. (91 aa)
	PDPK1	3-phosphoinositide dependent protein kinase-1. (542 aa)
	LCK	Tyrosine-protein kinase. (539 aa)
	STX4	STX4 isoform 4; Belongs to the syntaxin family. (297 aa)
	LOC745935	C-C motif chemokine. (87 aa)
	NSMAF	Neutral sphingomyelinase activation associated factor. (948 aa)
	CCL8	C-C motif chemokine. (109 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	FYN	ENSPTRP00000038032	ENSPTRP00000077482	BTK isoform 2.	Tyrosine-protein kinase.	0.599
BTK	LCK	ENSPTRP00000038032	ENSPTRP00000000842	BTK isoform 2.	Tyrosine-protein kinase.	0.517
CCL3	CCL5	ENSPTRP00000057009	ENSPTRP00000083031	C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family.	C-C motif chemokine.	0.528
CCL3	LOC745935	ENSPTRP00000057009	ENSPTRP00000079006	C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family.	C-C motif chemokine.	0.666
CCL5	CCL3	ENSPTRP00000083031	ENSPTRP00000057009	C-C motif chemokine.	C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5 (By similarity); Belongs to the intercrine beta (chemokine CC) family.	0.528
CCL5	CCL8	ENSPTRP00000083031	ENSPTRP00000015356	C-C motif chemokine.	C-C motif chemokine.	0.986
CCL5	LOC745935	ENSPTRP00000083031	ENSPTRP00000079006	C-C motif chemokine.	C-C motif chemokine.	0.704
CCL5	SRC	ENSPTRP00000083031	ENSPTRP00000076797	C-C motif chemokine.	Tyrosine-protein kinase.	0.595
CCL8	CCL5	ENSPTRP00000015356	ENSPTRP00000083031	C-C motif chemokine.	C-C motif chemokine.	0.986
CCL8	LOC745935	ENSPTRP00000015356	ENSPTRP00000079006	C-C motif chemokine.	C-C motif chemokine.	0.482
ENSPTRP00000072507	FYN	ENSPTRP00000072507	ENSPTRP00000077482	annotation not available	Tyrosine-protein kinase.	0.588
ENSPTRP00000072507	LCK	ENSPTRP00000072507	ENSPTRP00000000842	annotation not available	Tyrosine-protein kinase.	0.519
FYN	BTK	ENSPTRP00000077482	ENSPTRP00000038032	Tyrosine-protein kinase.	BTK isoform 2.	0.599
FYN	ENSPTRP00000072507	ENSPTRP00000077482	ENSPTRP00000072507	Tyrosine-protein kinase.	annotation not available	0.588
FYN	LCK	ENSPTRP00000077482	ENSPTRP00000000842	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.883
FYN	PDPK1	ENSPTRP00000077482	ENSPTRP00000090334	Tyrosine-protein kinase.	3-phosphoinositide dependent protein kinase-1.	0.579
FYN	SRC	ENSPTRP00000077482	ENSPTRP00000076797	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.999
LCK	BTK	ENSPTRP00000000842	ENSPTRP00000038032	Tyrosine-protein kinase.	BTK isoform 2.	0.517
LCK	ENSPTRP00000072507	ENSPTRP00000000842	ENSPTRP00000072507	Tyrosine-protein kinase.	annotation not available	0.519
LCK	FYN	ENSPTRP00000000842	ENSPTRP00000077482	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.883