STRINGSTRING
SRRM1 SRRM1 CLIC4 CLIC4 ZNF326 ZNF326 LRIF1 LRIF1 S100A10 S100A10 LMNA LMNA RNASEL RNASEL CENPF CENPF KIN KIN VIM VIM MEN1 MEN1 ARID2 ARID2 YEATS4 YEATS4 PSPC1 PSPC1 NUFIP1 NUFIP1 TEP1 TEP1 TINF2 TINF2 CFL2 CFL2 PSMA6 PSMA6 YY1 YY1 PML PML BLM BLM TP53 TP53 DCAF7 DCAF7 SMARCD2 SMARCD2 THOC1 THOC1 PIAS4 PIAS4 UHRF1 UHRF1 HNRNPM HNRNPM LGALS13 LGALS13 ZNF350 ZNF350 HAT1 HAT1 MORC3 MORC3 HLCS HLCS PHF5A PHF5A OGG1 OGG1 SMARCC1 SMARCC1 PRKCD PRKCD RGS12 RGS12 ERCC8 ERCC8 ENC1 ENC1 LMNB1-2 LMNB1-2 MATR3 MATR3 SPARC SPARC MYB MYB PHF10 PHF10 HNRNPA2B1 HNRNPA2B1 ACTL6B ACTL6B SRPK1 SRPK1 ZNF703 ZNF703 ARFGEF1 ARFGEF1 RAD21 RAD21 CK820_G0008402 CK820_G0008402 ENSPTRP00000036205 ENSPTRP00000036205 GFI1B GFI1B SMC1A SMC1A KIF4A KIF4A NONO NONO STAG2 STAG2 TENM1 TENM1 SMARCB1 SMARCB1 PRPF40A PRPF40A PBRM1 PBRM1 BCL11A BCL11A SMC3 SMC3 ATXN3 ATXN3 GMCL1 GMCL1 HLTF HLTF CASK CASK NSMF NSMF XPOT XPOT RUVBL1 RUVBL1 ATXN1 ATXN1 PAXIP1 PAXIP1 DNMT3A DNMT3A ATN1 ATN1 KAT8 KAT8 ENSPTRP00000061537 ENSPTRP00000061537 GHRHR GHRHR HES1 HES1 ENSPTRP00000064450 ENSPTRP00000064450 ACTL6B-2 ACTL6B-2 SNW1 SNW1 RUVBL2 RUVBL2 ENSPTRP00000066105 ENSPTRP00000066105 ENSPTRP00000066220 ENSPTRP00000066220 ALOX5 ALOX5 PPIG PPIG LOC457411 LOC457411 ENSPTRP00000067637 ENSPTRP00000067637 BASP1 BASP1 ENSPTRP00000067759 ENSPTRP00000067759 POLA1 POLA1 SMARCE1 SMARCE1 MBD1 MBD1 SFPQ SFPQ SMARCD1 SMARCD1 MORC2 MORC2 AHCTF1 AHCTF1 ACTL6A ACTL6A ENSPTRP00000073097 ENSPTRP00000073097 SMARCA4 SMARCA4 SATB1 SATB1 GHRHR-2 GHRHR-2 ENSPTRP00000073703 ENSPTRP00000073703 LOC739606 LOC739606 ENSPTRP00000074804 ENSPTRP00000074804 SPTBN4 SPTBN4 RUNX1T1 RUNX1T1 LOC454204 LOC454204 MAEA MAEA ENSPTRP00000076005 ENSPTRP00000076005 ENSPTRP00000076491 ENSPTRP00000076491 ENSPTRP00000076931 ENSPTRP00000076931 ENSPTRP00000077428 ENSPTRP00000077428 ENSPTRP00000077953 ENSPTRP00000077953 CK820_G0040570 CK820_G0040570 ENSPTRP00000078953 ENSPTRP00000078953 TGFB1I1 TGFB1I1 LOC460817 LOC460817 CXXC1 CXXC1 ENSPTRP00000079733 ENSPTRP00000079733 SATB2 SATB2 BRD7 BRD7 ENSPTRP00000081714 ENSPTRP00000081714 SMARCC2 SMARCC2 DGKQ DGKQ ENSPTRP00000082912 ENSPTRP00000082912 AKAP8 AKAP8 ENSPTRP00000083068 ENSPTRP00000083068 AKAP8L AKAP8L PHACTR3 PHACTR3 LMNB1 LMNB1 VDR VDR ANXA2 ANXA2 CENPW CENPW HNRNPU HNRNPU ATXN7 ATXN7 IFFO1 IFFO1 CEBPB CEBPB STAG1 STAG1 CAD CAD CFL1 CFL1 SORBS1 SORBS1 ENSPTRP00000088411 ENSPTRP00000088411 NCOR2 NCOR2 CK820_G0040570-2 CK820_G0040570-2 KRT8 KRT8 ENSPTRP00000089841 ENSPTRP00000089841 PHB2 PHB2 ENSPTRP00000091771 ENSPTRP00000091771 SCAF8 SCAF8 NUMA1 NUMA1 GFI1 GFI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRRM1SRRM1 isoform 3. (918 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
ZNF326Zinc finger protein 326; Belongs to the AKAP95 family. (582 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (769 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
LMNALMNA isoform 8; Belongs to the intermediate filament family. (664 aa)
RNASELRibonuclease L (2',5'-oligoisoadenylate synthetase-dependent). (741 aa)
CENPFCentromere protein F, 350/400kDa (Mitosin). (3114 aa)
KINKIN, antigenic determinant of recA protein homolog. (393 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
MEN1MEN1 isoform 14. (615 aa)
ARID2AT-rich interaction domain 2. (1835 aa)
YEATS4YEATS domain containing 4. (227 aa)
PSPC1Paraspeckle component 1. (508 aa)
NUFIP1Nuclear fragile X mental retardation protein interacting protein 1. (495 aa)
TEP1Telomerase associated protein 1. (2627 aa)
TINF2TERF1-interacting nuclear factor 2. (453 aa)
CFL2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
YY1YY1 transcription factor. (414 aa)
PMLPML isoform 6. (836 aa)
BLMBLM isoform 1. (1417 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
DCAF7DDB1 and CUL4 associated factor 7. (342 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
THOC1THOC1 isoform 2. (664 aa)
PIAS4Protein inhibitor of activated STAT protein 4. (510 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (856 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (730 aa)
LGALS13Galectin. (139 aa)
ZNF350Zinc finger protein 350. (532 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
HLCSHolocarboxylase synthetase (Biotin-(Proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase). (726 aa)
PHF5APHD finger protein 5A. (110 aa)
OGG18-oxoguanine DNA glycosylase. (424 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1. (1105 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
RGS12Regulator of G-protein signaling 12. (1447 aa)
ERCC8Excision repair cross-complementing rodent repair deficiency, complementation group 8. (396 aa)
ENC1Ectodermal-neural cortex (With BTB-like domain). (589 aa)
LMNB1-2LMNB1 isoform 1; Belongs to the intermediate filament family. (586 aa)
MATR3MATR3 isoform 14. (895 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
PHF10PHD finger protein 10. (498 aa)
HNRNPA2B1Heterogeneous nuclear ribonucleoprotein A2/B1. (353 aa)
ACTL6BACTL6B isoform 1; Belongs to the actin family. (426 aa)
SRPK1SRSF protein kinase 1. (655 aa)
ZNF703Zinc finger protein 703. (590 aa)
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited). (1849 aa)
RAD21RAD21 cohesin complex component. (631 aa)
CK820_G0008402Annexin. (233 aa)
ENSPTRP00000036205Keratin, type II cytoskeletal 8-like. (478 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (352 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1232 aa)
NONOnon-POU domain containing octamer binding. (471 aa)
STAG2Stromal antigen 2. (1268 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (394 aa)
PRPF40APRP40 pre-mRNA processing factor 40 homolog A. (930 aa)
PBRM1PBRM1 isoform 17. (1690 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
ATXN3ATXN3 isoform 4. (374 aa)
GMCL1Germ cell-less protein-like protein 1. (515 aa)
HLTFHelicase-like transcription factor. (1013 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (921 aa)
NSMFNSMF isoform 1. (530 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ATXN1ATXN1 isoform 2. (827 aa)
PAXIP1PAX interacting protein 1. (1067 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
ATN1Atrophin-1; Transcriptional corepressor. Corepressor of MTG8 transcriptional repression. Recruits NR2E1 to repress transcription. Has some intrinsic repression activity. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). (1224 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
ENSPTRP00000061537annotation not available (357 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSPTRP00000064450annotation not available (445 aa)
ACTL6B-2Actin like 6B. (426 aa)
SNW1SNW domain containing 1. (571 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ENSPTRP00000066105annotation not available (794 aa)
ENSPTRP00000066220annotation not available (211 aa)
ALOX5ALOX5 isoform 2. (785 aa)
PPIGPeptidylprolyl isomerase G (Cyclophilin G). (754 aa)
LOC457411Keratin, type II cytoskeletal 8 pseudogene. (503 aa)
ENSPTRP00000067637annotation not available (92 aa)
BASP1Brain abundant, membrane attached signal protein 1. (226 aa)
ENSPTRP00000067759annotation not available (739 aa)
POLA1DNA polymerase. (1468 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
MBD1Methyl-CpG binding domain protein 1. (630 aa)
SFPQSplicing factor proline/glutamine-rich. (677 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
MORC2MORC family CW-type zinc finger 2. (1032 aa)
AHCTF1AHCTF1 isoform 5. (2005 aa)
ACTL6AACTL6A isoform 2; Belongs to the actin family. (430 aa)
ENSPTRP00000073097annotation not available (202 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
SATB1DNA-binding protein SATB. (795 aa)
GHRHR-2Growth hormone-releasing hormone receptor isoform X1. (447 aa)
ENSPTRP00000073703annotation not available (710 aa)
LOC739606AHCTF1 isoform 2. (2232 aa)
ENSPTRP00000074804annotation not available (794 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2565 aa)
RUNX1T1RUNX1 translocation partner 1. (663 aa)
LOC454204Non-POU domain-containing octamer-binding protein. (445 aa)
MAEAMacrophage erythroblast attacher. (378 aa)
ENSPTRP00000076005annotation not available (354 aa)
ENSPTRP00000076491annotation not available (91 aa)
ENSPTRP00000076931annotation not available (350 aa)
ENSPTRP00000077428annotation not available (202 aa)
ENSPTRP00000077953annotation not available (451 aa)
CK820_G0040570PRKCZ isoform 2. (457 aa)
ENSPTRP00000078953annotation not available (150 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
LOC460817Bromodomain-containing protein 7 pseudogene. (397 aa)
CXXC1CXXC finger protein 1. (667 aa)
ENSPTRP00000079733annotation not available (1251 aa)
SATB2DNA-binding protein SATB. (733 aa)
BRD7Bromodomain containing 7. (652 aa)
ENSPTRP00000081714annotation not available (310 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa)
DGKQDiacylglycerol kinase. (952 aa)
ENSPTRP00000082912annotation not available (153 aa)
AKAP8A kinase (PRKA) anchor protein 8; Belongs to the AKAP95 family. (692 aa)
ENSPTRP00000083068annotation not available (421 aa)
AKAP8LA kinase (PRKA) anchor protein 8-like; Belongs to the AKAP95 family. (647 aa)
PHACTR3Phosphatase and actin regulator. (559 aa)
LMNB1Lamin B1. (586 aa)
VDRVitamin D (1,25-dihydroxyvitamin D3) receptor. (477 aa)
ANXA2Annexin. (357 aa)
CENPWCentromere protein W. (88 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
ATXN7ATXN7 isoform 2. (939 aa)
IFFO1Intermediate filament family orphan 1; Belongs to the intermediate filament family. (572 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
STAG1Stromal antigen 1. (1258 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2229 aa)
CFL1CFL1 isoform 2; Belongs to the actin-binding proteins ADF family. (204 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
ENSPTRP00000088411annotation not available (465 aa)
NCOR2Nuclear receptor corepressor 2. (2514 aa)
CK820_G0040570-2PRKCZ isoform 4. (95 aa)
KRT8KRT8 isoform 11; Belongs to the intermediate filament family. (483 aa)
ENSPTRP00000089841annotation not available (259 aa)
PHB2Prohibitin. (299 aa)
ENSPTRP00000091771annotation not available (149 aa)
SCAF8SR-related CTD associated factor 8. (1352 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2111 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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