STRINGSTRING
CHD5 CHD5 SRCAP SRCAP BRPF1 BRPF1 ENSPTRP00000074641 ENSPTRP00000074641 CREBBP CREBBP MORF4L1 MORF4L1 TAF5L TAF5L ZZZ3 ZZZ3 JADE3 JADE3 HCFC1-2 HCFC1-2 TEX30 TEX30 MCRS1 MCRS1 NAA50 NAA50 LEF1 LEF1 MEAF6 MEAF6 ZMPSTE24 ZMPSTE24 NAT15 NAT15 MRGBP MRGBP CK820_G0037203 CK820_G0037203 NCOA3 NCOA3 PHF20 PHF20 KAT14 KAT14 HAT1 HAT1 TAF1 TAF1 KANSL1-2 KANSL1-2 BRD1 BRD1 ENSPTRP00000088036 ENSPTRP00000088036 ENY2 ENY2 EPC2 EPC2 KANSL3 KANSL3 NCOA1 NCOA1 SPHK2 SPHK2 MBD3L1 MBD3L1 MLLT1 MLLT1 KAT7 KAT7 KANSL1 KANSL1 KAT2A KAT2A MSL1 MSL1 PCGF2 PCGF2 TADA2A TADA2A USP22 USP22 TRIM16-2 TRIM16-2 SF3B3 SF3B3 SGF29 SGF29 MBIP MBIP BRCA2 BRCA2 ENSPTRP00000009603 ENSPTRP00000009603 YEATS4 YEATS4 ING4 ING4 KAT5 KAT5 MYOD1 MYOD1 KAT6B KAT6B EPC1 EPC1 CRTC2 CRTC2 VPS72 VPS72 ATXN7L2 ATXN7L2 DR1 DR1 GTF2B GTF2B TAF12 TAF12 HNF1A HNF1A SPI1 SPI1 ING3-2 ING3-2 TAF9 TAF9 JADE2 JADE2 MECP2 MECP2 SUPT3H SUPT3H KANSL2 KANSL2 ENSPTRP00000087807 ENSPTRP00000087807 MBTD1 MBTD1 PBXIP1 PBXIP1 ATXN7L1-2 ATXN7L1-2 ATXN7 ATXN7 TRIM16 TRIM16 MLLT3 MLLT3 BRPF3 BRPF3 TAF6L TAF6L TAF6 TAF6 CK820_G0054728 CK820_G0054728 ATF2 ATF2 TAF5 TAF5 PER1 PER1 ACTL6B-2 ACTL6B-2 ENSPTRP00000064849 ENSPTRP00000064849 ATXN7L1 ATXN7L1 RUVBL2 RUVBL2 PAX6 PAX6 ENSPTRP00000066334 ENSPTRP00000066334 TADA1 TADA1 KAT8 KAT8 TAF10 TAF10 TAF4 TAF4 ACTB ACTB MAP3K7 MAP3K7 TAF2 TAF2 RUVBL1 RUVBL1 NAA40 NAA40 DMAP1 DMAP1 TRRAP TRRAP SUPT7L SUPT7L MBD3 MBD3 EP400 EP400 LDB1 LDB1 HCFC1 HCFC1 FOXP3 FOXP3 ENSPTRP00000037477 ENSPTRP00000037477 GTF3C4 GTF3C4 POLE3 POLE3 KAT6A KAT6A CPA4 CPA4 ING3 ING3 ACTL6B ACTL6B SF3B5 SF3B5 BEND3 BEND3 IRF4 IRF4 BRD8 BRD8 CLOCK CLOCK TADA2B TADA2B YEATS2 YEATS2 MSL2 MSL2 EOMES EOMES KAT2B KAT2B TADA3 TADA3 EP300 EP300 MCM3AP MCM3AP OGT OGT JADE1 JADE1 PHF20-2 PHF20-2 PHF20L1 PHF20L1 ENSPTRP00000069337 ENSPTRP00000069337 ENSPTRP00000069606 ENSPTRP00000069606 ATXN7L3 ATXN7L3 ING5 ING5 ENSPTRP00000070717 ENSPTRP00000070717 SUPT20H SUPT20H LOC461609 LOC461609 WDR5 WDR5 MED24 MED24 ACTL6A ACTL6A NAA60 NAA60 ENSPTRP00000072986 ENSPTRP00000072986 MSL3 MSL3 CK820_G0021068 CK820_G0021068 APBB1 APBB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD5Chromodomain helicase DNA binding protein 5. (1955 aa)
SRCAPT0179181 isoform 1. (3227 aa)
BRPF1Bromodomain and PHD finger containing, 1. (1253 aa)
ENSPTRP00000074641annotation not available (485 aa)
CREBBPCREB binding protein. (2442 aa)
MORF4L1Mortality factor 4 like 1. (363 aa)
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (589 aa)
ZZZ3Zinc finger, ZZ-type containing 3. (903 aa)
JADE3PHD finger protein 16. (823 aa)
HCFC1-2HCFC1 isoform 1. (2035 aa)
TEX30Chromosome 13 open reading frame 27. (227 aa)
MCRS1Microspherule protein 1. (475 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
MEAF6MYST/Esa1 associated factor 6. (201 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (480 aa)
NAT15Uncharacterized LOC100609520. (183 aa)
MRGBPChromosome 20 open reading frame 20. (204 aa)
CK820_G0037203TAF4 isoform 5. (635 aa)
NCOA3Nuclear receptor coactivator. (1426 aa)
PHF20PHD finger protein 20. (1012 aa)
KAT14Lysine acetyltransferase 14. (782 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
KANSL1-2KAT8 regulatory NSL complex subunit 1. (1105 aa)
BRD1Bromodomain containing 1. (1189 aa)
ENSPTRP00000088036annotation not available (243 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (100 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
KANSL3KAT8 regulatory NSL complex subunit 3. (878 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
SPHK2Sphingosine kinase 2. (255 aa)
MBD3L1Methyl-CpG binding domain protein 3 like 1. (194 aa)
MLLT1Myeloid/lymphoid or mixed-lineage leukemia translocated to, 1. (559 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (1105 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
MSL1MSL complex subunit 1. (614 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
TADA2ATranscriptional adapter. (443 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa)
TRIM16-2Tripartite motif containing 16. (560 aa)
SF3B3Splicing factor 3b, subunit 3, 130kDa. (1217 aa)
SGF29SGF29 isoform 6. (265 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
BRCA2Breast cancer 2, early onset. (3418 aa)
ENSPTRP00000009603annotation not available (419 aa)
YEATS4YEATS domain containing 4. (227 aa)
ING4Inhibitor of growth protein. (249 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (320 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2070 aa)
EPC1Enhancer of polycomb homolog. (836 aa)
CRTC2CREB regulated transcription coactivator 2. (701 aa)
VPS72Vacuolar protein sorting 72 homolog. (375 aa)
ATXN7L2ATXN7L2 isoform 2. (722 aa)
DR1Down-regulator of transcription 1, TBP-binding (Negative cofactor 2). (176 aa)
GTF2BGeneral transcription factor IIB. (310 aa)
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa)
HNF1AHNF1 homeobox A. (662 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
ING3-2Inhibitor of growth family member 3. (418 aa)
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa)
JADE2Jade family PHD finger 2. (834 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (424 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (675 aa)
ENSPTRP00000087807annotation not available (481 aa)
MBTD1Mbt domain containing 1. (630 aa)
PBXIP1Pre-B-cell leukemia homeobox interacting protein 1. (731 aa)
ATXN7L1-2ATXN7L1 isoform 1. (860 aa)
ATXN7ATXN7 isoform 2. (939 aa)
TRIM16T0195358 isoform 1. (564 aa)
MLLT3MLLT3 isoform 1. (570 aa)
BRPF3Bromodomain and PHD finger containing, 3. (1205 aa)
TAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (603 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
CK820_G0054728MECP2 isoform 14. (493 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TAF5TATA-box binding protein associated factor 5. (803 aa)
PER1Period circadian regulator 1. (1290 aa)
ACTL6B-2Actin like 6B. (426 aa)
ENSPTRP00000064849annotation not available (150 aa)
ATXN7L1ATXN7L1 isoform 3. (963 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
PAX6PAX6 isoform 13. (436 aa)
ENSPTRP00000066334annotation not available (316 aa)
TADA1Transcriptional adaptor 1. (335 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa. (1199 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
NAA40N(Alpha)-acetyltransferase 40, NatD catalytic subunit, homolog. (237 aa)
DMAP1DNA methyltransferase 1-associated protein 1. (467 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (414 aa)
MBD3Methyl-CpG binding domain protein 3. (291 aa)
EP400EP400 isoform 1. (3130 aa)
LDB1LIM domain binding 1. (411 aa)
HCFC1Host cell factor C1. (2080 aa)
FOXP3FOXP3 isoform 4. (456 aa)
ENSPTRP00000037477Jade family PHD finger 3. (279 aa)
GTF3C4General transcription factor IIIC subunit 4. (822 aa)
POLE3Polymerase (DNA directed), epsilon 3 (P17 subunit). (147 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa)
CPA4Carboxypeptidase A4. (421 aa)
ING3Inhibitor of growth protein. (418 aa)
ACTL6BACTL6B isoform 1; Belongs to the actin family. (426 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
BEND3BEN domain containing 3. (828 aa)
IRF4Interferon regulatory factor 4. (451 aa)
BRD8Bromodomain containing 8. (1235 aa)
CLOCKClock circadian regulator. (847 aa)
TADA2BTranscriptional adapter. (420 aa)
YEATS2YEATS domain containing 2. (1416 aa)
MSL2Male-specific lethal 2 homolog. (577 aa)
EOMESEOMES isoform 2. (704 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
TADA3Transcriptional adaptor 3. (432 aa)
EP300E1A binding protein p300. (2175 aa)
MCM3APMCM3AP isoform 1. (1981 aa)
OGTOGT isoform 6. (1057 aa)
JADE1Jade family PHD finger 1. (842 aa)
PHF20-2PHD finger protein 20. (103 aa)
PHF20L1PHD finger protein 20-like 1. (1022 aa)
ENSPTRP00000069337annotation not available (165 aa)
ENSPTRP00000069606LOW QUALITY PROTEIN: putative male-specific lethal-3 protein-like 2. (481 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
ING5Inhibitor of growth family member 5. (254 aa)
ENSPTRP00000070717annotation not available (287 aa)
SUPT20HSPT20 homolog, SAGA complex component. (811 aa)
LOC461609Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] (323 aa)
WDR5WD repeat domain 5. (334 aa)
MED24Mediator complex subunit 24. (1008 aa)
ACTL6AACTL6A isoform 2; Belongs to the actin family. (430 aa)
NAA60N(alpha)-acetyltransferase 60, NatF catalytic subunit. (249 aa)
ENSPTRP00000072986annotation not available (244 aa)
MSL3Male-specific lethal 3 homolog. (521 aa)
CK820_G0021068Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (341 aa)
APBB1APBB1 isoform 4. (772 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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