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USP48 USP48 USP49 USP49 ATXN7 ATXN7 ENSPTRP00000085145 ENSPTRP00000085145 UCHL5 UCHL5 MYSM1 MYSM1 CK820_G0048521 CK820_G0048521 USP3 USP3 TAF9 TAF9 ENSPTRP00000083584 ENSPTRP00000083584 ENSPTRP00000083257 ENSPTRP00000083257 CYLD CYLD CCDC197 CCDC197 USP11 USP11 OTUD1 OTUD1 USP10 USP10 UIMC1 UIMC1 PRR27 PRR27 USP40-2 USP40-2 SHMT1 SHMT1 USP7 USP7 TAF5L TAF5L BARD1 BARD1 YOD1 YOD1 OTUB1 OTUB1 USP15 USP15 ENSPTRP00000073543 ENSPTRP00000073543 ENSPTRP00000072950 ENSPTRP00000072950 BRCC3 BRCC3 LOC107967429 LOC107967429 USP34 USP34 ENSPTRP00000071805 ENSPTRP00000071805 ASXL1 ASXL1 SUPT20H SUPT20H ENSPTRP00000070717 ENSPTRP00000070717 USP51 USP51 ATXN7L3 ATXN7L3 ZC3H12A ZC3H12A USP9X USP9X USP25 USP25 USP8 USP8 OTUD6A OTUD6A TADA1 TADA1 USP42-2 USP42-2 USP12 USP12 ATXN7L1 ATXN7L1 MINDY4 MINDY4 TAF5 TAF5 USP16 USP16 STAMBPL1 STAMBPL1 TAF6 TAF6 TAF6L TAF6L SHMT2 SHMT2 CK820_G0056493 CK820_G0056493 WDR48 WDR48 MINDY4B MINDY4B CK820_G0003646 CK820_G0003646 CK820_G0056962 CK820_G0056962 CK820_G0056407 CK820_G0056407 TAF10 TAF10 ENSPTRP00000060087 ENSPTRP00000060087 TAF4 TAF4 ENSPTRP00000058703 ENSPTRP00000058703 USP47 USP47 USP14 USP14 USP6 USP6 ABRAXAS1 ABRAXAS1 TAF2 TAF2 USP43 USP43 USP21 USP21 USP50 USP50 CDK1 CDK1 USP5 USP5 CK820_G0007206 CK820_G0007206 USP45 USP45 USP26 USP26 TRRAP TRRAP USP19 USP19 SUPT7L SUPT7L ABRAXAS2 ABRAXAS2 ATXN3 ATXN3 COPS5 COPS5 MINDY1 MINDY1 USP33 USP33 USP9Y USP9Y OTUD5 OTUD5 USP20 USP20 OTUD6B OTUD6B VCPIP1 VCPIP1 USP42 USP42 PRKN PRKN SF3B5 SF3B5 TNFAIP3 TNFAIP3 OTULIN OTULIN OTUD4 OTUD4 USP38 USP38 USP53 USP53 TADA2B TADA2B USP13 USP13 BAP1 BAP1 USP4 USP4 TADA3 TADA3 JOSD1 JOSD1 USP18 USP18 CK820_G0037203 CK820_G0037203 SPATA2 SPATA2 USP40 USP40 PSMD14 PSMD14 USP39 USP39 STAMBP STAMBP JOSD2 JOSD2 BABAM1 BABAM1 USP36 USP36 USP32 USP32 KAT2A KAT2A EPOP EPOP USP22 USP22 SF3B3 SF3B3 SGF29 SGF29 USP31 USP31 ENSPTRP00000012172 ENSPTRP00000012172 OTUD7A OTUD7A OTUB2 OTUB2 USP30 USP30 USP44 USP44 USP2 USP2 EIF3F EIF3F ZRANB1 ZRANB1 USP54 USP54 MINDY3 MINDY3 OTUD7B OTUD7B ATXN7L2 ATXN7L2 USP1 USP1 USP24 USP24 TAF12 TAF12 OTUD3 OTUD3 USP37 USP37 DESI2 DESI2 UCHL1 UCHL1 CK820_G0008602 CK820_G0008602 ENSPTRP00000092677 ENSPTRP00000092677 SENP8 SENP8 BABAM2 BABAM2 LOC466759 LOC466759 OTULINL OTULINL USP30-2 USP30-2 USP46 USP46 MINDY2 MINDY2 USP28 USP28 ENSPTRP00000088036 ENSPTRP00000088036 ENY2 ENY2 ENSPTRP00000087891 ENSPTRP00000087891 SUPT3H SUPT3H ATXN7L1-2 ATXN7L1-2 USP35 USP35 LOC104001961 LOC104001961
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USP48Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1035 aa)
USP49Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (688 aa)
ATXN7ATXN7 isoform 2. (939 aa)
ENSPTRP00000085145annotation not available (447 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (393 aa)
MYSM1Myb-like, SWIRM and MPN domains 1. (828 aa)
CK820_G0048521USP32 isoform 6. (390 aa)
USP3Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (520 aa)
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa)
ENSPTRP00000083584annotation not available (275 aa)
ENSPTRP00000083257annotation not available (412 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
CCDC197Coiled-coil domain containing 197. (272 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (972 aa)
OTUD1OTUD1 isoform 1. (481 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa)
UIMC1Ubiquitin interaction motif containing 1. (722 aa)
PRR27PRR27 isoform 2. (219 aa)
USP40-2Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (98 aa)
SHMT1Serine hydroxymethyltransferase 1. (483 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1121 aa)
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (589 aa)
BARD1BRCA1 associated RING domain 1. (777 aa)
YOD1YOD1 deubiquitinase. (348 aa)
OTUB1OTUB1 isoform 1. (299 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
ENSPTRP00000073543annotation not available (336 aa)
ENSPTRP00000072950annotation not available (65 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (317 aa)
LOC107967429Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (476 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3546 aa)
ENSPTRP00000071805annotation not available (188 aa)
ASXL1ASXL transcriptional regulator 1. (1548 aa)
SUPT20HSPT20 homolog, SAGA complex component. (811 aa)
ENSPTRP00000070717annotation not available (287 aa)
USP51Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (711 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
USP9XUbiquitin specific peptidase 9, X-linked; Belongs to the peptidase C19 family. (2591 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1125 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1110 aa)
OTUD6AOTU deubiquitinase 6A. (288 aa)
TADA1Transcriptional adaptor 1. (335 aa)
USP42-2USP42 isoform 3; Belongs to the peptidase C19 family. (1327 aa)
USP12Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family. (372 aa)
ATXN7L1ATXN7L1 isoform 3. (963 aa)
MINDY4Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X2. (762 aa)
TAF5TATA-box binding protein associated factor 5. (803 aa)
USP16Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (826 aa)
STAMBPL1STAM binding protein like 1. (461 aa)
TAF6TATA-box binding protein associated factor 6. (714 aa)
TAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (603 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
CK820_G0056493USP41 isoform 3; Belongs to the peptidase C19 family. (209 aa)
WDR48WD repeat domain 48. (684 aa)
MINDY4BInactive ubiquitin carboxyl-terminal hydrolase MINDY-4B. (460 aa)
CK820_G0003646ABRAXAS1 isoform 9. (311 aa)
CK820_G0056962USP17L8 isoform 1. (367 aa)
CK820_G0056407Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (388 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
ENSPTRP00000060087annotation not available (128 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
ENSPTRP00000058703annotation not available (370 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
USP14Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibi [...] (493 aa)
USP6USP6 isoform 5; Belongs to the peptidase C19 family. (1385 aa)
ABRAXAS1Family with sequence similarity 175, member A. (409 aa)
TAF2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa. (1199 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1123 aa)
USP21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa)
USP50USP50 isoform 2; Belongs to the peptidase C19 family. (276 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa)
CK820_G0007206USP49 isoform 3. (557 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (814 aa)
USP26Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (915 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
USP19USP19 isoform 6. (1421 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (414 aa)
ABRAXAS2Family with sequence similarity 175, member B. (415 aa)
ATXN3ATXN3 isoform 4. (374 aa)
COPS5COP9 constitutive photomorphogenic homolog subunit 5. (334 aa)
MINDY1MINDY lysine 48 deubiquitinase 1. (517 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (942 aa)
USP9YUSP9Y isoform 1; Belongs to the peptidase C19 family. (2523 aa)
OTUD5OTU deubiquitinase 5. (598 aa)
USP20Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (914 aa)
OTUD6BOTU domain containing 6B. (323 aa)
VCPIP1Valosin containing protein (P97)/p47 complex interacting protein 1. (1224 aa)
USP42Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (1316 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
TNFAIP3Tumor necrosis factor, alpha-induced protein 3. (790 aa)
OTULINOTULIN isoform 1. (352 aa)
OTUD4OTU deubiquitinase 4. (1114 aa)
USP38Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family. (1042 aa)
USP53Ubiquitin specific peptidase 53. (1073 aa)
TADA2BTranscriptional adapter. (420 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (962 aa)
TADA3Transcriptional adaptor 3. (432 aa)
JOSD1Josephin domain containing 1. (202 aa)
USP18USP domain-containing protein; Belongs to the peptidase C19 family. (372 aa)
CK820_G0037203TAF4 isoform 5. (635 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1247 aa)
PSMD14Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa)
USP39Ubiquitin specific peptidase 39. (565 aa)
STAMBPSTAM binding protein. (424 aa)
JOSD2Josephin domain containing 2. (188 aa)
BABAM1Chromosome 19 open reading frame 62. (329 aa)
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1123 aa)
USP32USP32 isoform 15. (557 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (837 aa)
EPOPElongin BC and polycomb repressive complex 2 associated protein. (379 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa)
SF3B3Splicing factor 3b, subunit 3, 130kDa. (1217 aa)
SGF29SGF29 isoform 6. (265 aa)
USP31USP31 isoform 2; Belongs to the peptidase C19 family. (1352 aa)
ENSPTRP00000012172MINDY lysine 48 deubiquitinase 2. (170 aa)
OTUD7AOTU deubiquitinase 7A. (924 aa)
OTUB2OTU deubiquitinase, ubiquitin aldehyde binding 2. (234 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
USP44Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (712 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (361 aa)
ZRANB1Zinc finger, RAN-binding domain containing 1. (734 aa)
USP54Ubiquitin specific peptidase 54. (1684 aa)
MINDY3Family with sequence similarity 188, member A. (445 aa)
OTUD7BOTU domain containing 7B. (843 aa)
ATXN7L2ATXN7L2 isoform 2. (722 aa)
USP1Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (785 aa)
USP24Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2619 aa)
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa)
OTUD3OTU domain containing 3. (398 aa)
USP37Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (979 aa)
DESI2PPPDE peptidase domain containing 1. (194 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (260 aa)
CK820_G0008602USP8 isoform 7. (973 aa)
ENSPTRP00000092677annotation not available (711 aa)
SENP8SUMO/sentrin specific peptidase family member 8. (212 aa)
BABAM2BRISC and BRCA1-A complex member 2 isoform X2. (415 aa)
LOC466759COP9 signalosome complex subunit 5 pseudogene. (334 aa)
OTULINLFAM105A isoform 2. (356 aa)
USP30-2Ubiquitin specific peptidase 30. (517 aa)
USP46Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (368 aa)
MINDY2Family with sequence similarity 63, member B. (534 aa)
USP28USP28 isoform 2; Belongs to the peptidase C19 family. (1192 aa)
ENSPTRP00000088036annotation not available (243 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (100 aa)
ENSPTRP00000087891annotation not available (333 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (424 aa)
ATXN7L1-2ATXN7L1 isoform 1. (860 aa)
USP35USP35 isoform 4; Belongs to the peptidase C19 family. (1018 aa)
LOC104001961USP10 isoform 3. (709 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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