STRINGSTRING
PLXNA2 PLXNA2 PLXNB2 PLXNB2 PLXNA1 PLXNA1 PLXNC1 PLXNC1 PLXNA4 PLXNA4 NRP1 NRP1 PLXNA3 PLXNA3 NRP2 NRP2 PLXNB3 PLXNB3 PLXND1 PLXND1 PLXNB1 PLXNB1 MET MET
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXNA2PLXNA2 isoform 1. (1909 aa)
PLXNB2PLXNB2 isoform 1. (1838 aa)
PLXNA1PLXNA1 isoform 1. (1915 aa)
PLXNC1PLXNC1 isoform 1. (1568 aa)
PLXNA4PLXNA4 isoform 1. (1894 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
PLXNB3PLXNB3 isoform 1. (1932 aa)
PLXND1PLXND1 isoform 1. (1925 aa)
PLXNB1PLXNB1 isoform 1. (2135 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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