18 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GDNF	Glial cell derived neurotrophic factor. (228 aa)
	GSX2	GSX2 isoform 2. (304 aa)
	GSX1	GSX1 isoform 1. (264 aa)
	LHX5	LHX5 isoform 2. (402 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	DRGX	Dorsal root ganglia homeobox. (263 aa)
	LMO4	LIM domain only 4. (165 aa)
	DRAXIN	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
	HOXB8	HOXB8 isoform 1. (243 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (232 aa)
	DAAM2	Dishevelled associated activator of morphogenesis 2. (1077 aa)
	PBX3	PBX homeobox 3. (455 aa)
	UNCX	UNCX isoform 1. (531 aa)
	LHX3	LHX3 isoform 2. (402 aa)
	LHX1	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1. (955 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	GSX1	ENSPTRP00000077846	ENSPTRP00000009768	Achaete-scute family bHLH transcription factor 1.	GSX1 isoform 1.	0.495
ASCL1	GSX2	ENSPTRP00000077846	ENSPTRP00000027634	Achaete-scute family bHLH transcription factor 1.	GSX2 isoform 2.	0.594
ASCL1	LHX1	ENSPTRP00000077846	ENSPTRP00000054548	Achaete-scute family bHLH transcription factor 1.	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	0.551
ASCL1	LHX3	ENSPTRP00000077846	ENSPTRP00000063429	Achaete-scute family bHLH transcription factor 1.	LHX3 isoform 2.	0.400
GSX1	ASCL1	ENSPTRP00000009768	ENSPTRP00000077846	GSX1 isoform 1.	Achaete-scute family bHLH transcription factor 1.	0.495
GSX2	ASCL1	ENSPTRP00000027634	ENSPTRP00000077846	GSX2 isoform 2.	Achaete-scute family bHLH transcription factor 1.	0.594
HOXB8	PBX3	ENSPTRP00000089697	ENSPTRP00000067180	HOXB8 isoform 1.	PBX homeobox 3.	0.574
LHX1	ASCL1	ENSPTRP00000054548	ENSPTRP00000077846	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	Achaete-scute family bHLH transcription factor 1.	0.551
LHX3	ASCL1	ENSPTRP00000063429	ENSPTRP00000077846	LHX3 isoform 2.	Achaete-scute family bHLH transcription factor 1.	0.400
PBX3	HOXB8	ENSPTRP00000067180	ENSPTRP00000089697	PBX homeobox 3.	HOXB8 isoform 1.	0.574
PROX1	UNCX	ENSPTRP00000051173	ENSPTRP00000064731	Prospero homeobox 1.	UNCX isoform 1.	0.524
UNCX	PROX1	ENSPTRP00000064731	ENSPTRP00000051173	UNCX isoform 1.	Prospero homeobox 1.	0.524
WNT1	WNT3A	ENSPTRP00000008364	ENSPTRP00000051074	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.705
WNT3A	WNT1	ENSPTRP00000051074	ENSPTRP00000008364	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.705