24 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC25A46	Solute carrier family 25, member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
	OPHN1	Oligophrenin-1; Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at pre- synaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity). (810 aa)
	RORA	RAR-related orphan receptor A. (555 aa)
	GRID2	Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
	ENSPTRP00000081136	LOW QUALITY PROTEIN: uncharacterized protein LOC100614654. (148 aa)
	NRXN1	NRXN1 isoform 9. (1547 aa)
	AGTPBP1	ATP/GTP binding protein 1. (1290 aa)
	WNT7A	Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
	ATP7A	ATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
	LHX1	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
	GATA2	GATA binding protein 2. (480 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	CEND1	Cell cycle exit and neuronal differentiation 1. (149 aa)
	MTPN	MTPN isoform 1. (118 aa)
	LDB1	LIM domain binding 1. (411 aa)
	PHOX2B	Paired like homeobox 2B. (314 aa)
	TTLL1	Tubulin tyrosine ligase-like family, member 1. (404 aa)
	TTC21B	Tetratricopeptide repeat domain 21B. (1316 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	CBLN1	Cerebellin 1 precursor. (193 aa)
	HERC1	Hect (Homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1. (4861 aa)
	LHX5	LHX5 isoform 2. (402 aa)
	FAIM2	FAIM2 isoform 2; Belongs to the BI1 family. (316 aa)
	KNDC1	KNDC1 isoform 1. (1672 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGTPBP1	TTLL1	ENSPTRP00000069248	ENSPTRP00000024920	ATP/GTP binding protein 1.	Tubulin tyrosine ligase-like family, member 1.	0.461
CBLN1	GRID2	ENSPTRP00000013823	ENSPTRP00000083033	Cerebellin 1 precursor.	Glutamate ionotropic receptor delta type subunit 2.	0.900
CBLN1	NRXN1	ENSPTRP00000013823	ENSPTRP00000073023	Cerebellin 1 precursor.	NRXN1 isoform 9.	0.894
GATA2	LDB1	ENSPTRP00000054198	ENSPTRP00000040252	GATA binding protein 2.	LIM domain binding 1.	0.784
GATA2	PHOX2B	ENSPTRP00000054198	ENSPTRP00000027552	GATA binding protein 2.	Paired like homeobox 2B.	0.486
GRID2	CBLN1	ENSPTRP00000083033	ENSPTRP00000013823	Glutamate ionotropic receptor delta type subunit 2.	Cerebellin 1 precursor.	0.900
GRID2	NRXN1	ENSPTRP00000083033	ENSPTRP00000073023	Glutamate ionotropic receptor delta type subunit 2.	NRXN1 isoform 9.	0.791
LDB1	GATA2	ENSPTRP00000040252	ENSPTRP00000054198	LIM domain binding 1.	GATA binding protein 2.	0.784
LDB1	LHX1	ENSPTRP00000040252	ENSPTRP00000054548	LIM domain binding 1.	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	0.649
LDB1	LHX5	ENSPTRP00000040252	ENSPTRP00000009320	LIM domain binding 1.	LHX5 isoform 2.	0.497
LHX1	LDB1	ENSPTRP00000054548	ENSPTRP00000040252	LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).	LIM domain binding 1.	0.649
LHX5	LDB1	ENSPTRP00000009320	ENSPTRP00000040252	LHX5 isoform 2.	LIM domain binding 1.	0.497
NRXN1	CBLN1	ENSPTRP00000073023	ENSPTRP00000013823	NRXN1 isoform 9.	Cerebellin 1 precursor.	0.894
NRXN1	GRID2	ENSPTRP00000073023	ENSPTRP00000083033	NRXN1 isoform 9.	Glutamate ionotropic receptor delta type subunit 2.	0.791
PHOX2B	GATA2	ENSPTRP00000027552	ENSPTRP00000054198	Paired like homeobox 2B.	GATA binding protein 2.	0.486
TTLL1	AGTPBP1	ENSPTRP00000024920	ENSPTRP00000069248	Tubulin tyrosine ligase-like family, member 1.	ATP/GTP binding protein 1.	0.461