STRINGSTRING
ENSPTRP00000078003 ENSPTRP00000078003 BAD BAD MCPH1 MCPH1 ENSPTRP00000093022 ENSPTRP00000093022 CDH2 CDH2 BAX BAX SUN1-2 SUN1-2 NR2E1-2 NR2E1-2 PTEN PTEN ENSPTRP00000090501 ENSPTRP00000090501 EZH2-2 EZH2-2 ENSPTRP00000089750 ENSPTRP00000089750 ENSPTRP00000089450 ENSPTRP00000089450 ENSPTRP00000089256 ENSPTRP00000089256 ENSPTRP00000088766 ENSPTRP00000088766 ENSPTRP00000088754 ENSPTRP00000088754 CDK5R2 CDK5R2 PHLPP2 PHLPP2 ENSPTRP00000086358 ENSPTRP00000086358 LOC459638 LOC459638 ENSPTRP00000085189 ENSPTRP00000085189 SRD5A2 SRD5A2 MDK MDK ENSPTRP00000085036 ENSPTRP00000085036 LHX6 LHX6 ENSPTRP00000084830 ENSPTRP00000084830 DMD-2 DMD-2 ENSPTRP00000084287 ENSPTRP00000084287 KIRREL3 KIRREL3 CRK CRK GART-2 GART-2 ENSPTRP00000082446 ENSPTRP00000082446 MBOAT7-2 MBOAT7-2 GSK3B GSK3B FAM205A FAM205A TMEM14B TMEM14B CDK5 CDK5 ENSPTRP00000080117 ENSPTRP00000080117 DCLK2 DCLK2 FEZF2 FEZF2 LEF1 LEF1 SLIT2 SLIT2 LOC107974864 LOC107974864 DISC1 DISC1 ENSPTRP00000078419 ENSPTRP00000078419 ENSPTRP00000078378 ENSPTRP00000078378 LOC107971060 LOC107971060 PAFAH1B1 PAFAH1B1 EFHC1 EFHC1 SLC2A1 SLC2A1 ASCL1 ASCL1 NTRK2 NTRK2 EZH2 EZH2 UQCRQ UQCRQ NEFL NEFL LOC100611979 LOC100611979 HDAC1 HDAC1 FGF8 FGF8 SUN1 SUN1 ENSPTRP00000075494 ENSPTRP00000075494 NSUN5-2 NSUN5-2 POU3F3 POU3F3 ROBO1 ROBO1 NDE1 NDE1 PPP1R9B PPP1R9B NR2E1 NR2E1 NKX2-1 NKX2-1 HTR5A-2 HTR5A-2 MGARP MGARP NF2 NF2 ID4 ID4 FOXP2 FOXP2 NDEL1-2 NDEL1-2 ARX ARX EGFR EGFR ZIC1 ZIC1 DMD DMD ATP2B4 ATP2B4 LAMB1 LAMB1 ENSPTRP00000068866 ENSPTRP00000068866 CDON CDON ATP1A3 ATP1A3 PEX5 PEX5 SYNE2 SYNE2 PHACTR1 PHACTR1 DCX DCX SMO-2 SMO-2 TMEM108 TMEM108 FGF13 FGF13 LOC748850 LOC748850 ZIC3 ZIC3 PAX6 PAX6 DRD1 DRD1 ENSPTRP00000065099 ENSPTRP00000065099 ENSPTRP00000065012 ENSPTRP00000065012 CNTNAP2 CNTNAP2 TSC1 TSC1 KDM1A KDM1A FAT4 FAT4 MBOAT7 MBOAT7 EMX1 EMX1 BBS4 BBS4 RELN RELN DAB2IP DAB2IP RTN4 RTN4 ADGRG1 ADGRG1 CSNK2A2 CSNK2A2 ATOH1 ATOH1 RARA RARA CDK5R1 CDK5R1 FOXG1 FOXG1 DAB1 DAB1 HSD3B2 HSD3B2 BCAN BCAN ASPM ASPM SRGAP2 SRGAP2 PROX1 PROX1 WNT3A WNT3A PAX5 PAX5 SCT SCT TENT2 TENT2 TSKU TSKU SUN2 SUN2 MDGA1 MDGA1 CRKL CRKL TBR1 TBR1 GART GART CTNNB1 CTNNB1 MFSD2A MFSD2A ATIC ATIC XAB2 XAB2 DLX1 DLX1 PLXNA3 PLXNA3 LHX2 LHX2 TRAPPC9 TRAPPC9 TACC1 TACC1 FUT10 FUT10 HTR5A HTR5A SMO SMO CDK6 CDK6 NSUN5 NSUN5 OGDH OGDH GLI3 GLI3 NEUROD6 NEUROD6 NPY NPY MAS1 MAS1 DIXDC1 DIXDC1 AKIRIN2 AKIRIN2 SRF SRF ATAT1 ATAT1 CEP120 CEP120 SRD5A1 SRD5A1 ANXA3 ANXA3 UBA6 UBA6 EPHA5 EPHA5 TACC3 TACC3 FBXO45 FBXO45 TRA2B TRA2B EIF2B5 EIF2B5 RHOA RHOA EOMES EOMES SLC32A1 SLC32A1 XRN2 XRN2 BTBD3 BTBD3 MKKS MKKS PLCB1 PLCB1 COL3A1 COL3A1 CCDC141 CCDC141 DLX2 DLX2 PEX13 PEX13 ALK ALK WDR62 WDR62 PTPRS PTPRS SEMA6B SEMA6B NARS1 NARS1 IGF2BP1 IGF2BP1 EZH1 EZH1 NF1 NF1 NDEL1 NDEL1 YWHAE YWHAE BBS2 BBS2 BMERB1 BMERB1 IGF1R IGF1R CCDC85C CCDC85C PSEN1 PSEN1 MPP5 MPP5 HIF1A HIF1A LHX5 LHX5 KCNA1 KCNA1 FEZ1 FEZ1 H2AFX H2AFX BBS1 BBS1 TH TH BNIP3 BNIP3 TACC2 TACC2 EMX2 EMX2 ZMIZ1 ZMIZ1 BTG2 BTG2 KIF14 KIF14 LMX1A LMX1A HSD3B1 HSD3B1 LRP8 LRP8 DMRTA2 DMRTA2 HTR6 HTR6
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000078003annotation not available (847 aa)
BADBcl2-associated agonist of cell death. (168 aa)
MCPH1Microcephalin; Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity). (851 aa)
ENSPTRP00000093022annotation not available (563 aa)
CDH2Cadherin 2, type 1, N-cadherin (Neuronal); Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
BAXBAX isoform 7. (123 aa)
SUN1-2SUN1 isoform 10. (904 aa)
NR2E1-2Nuclear receptor subfamily 2 group E member 1. (385 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ENSPTRP00000090501annotation not available (192 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
ENSPTRP00000089750annotation not available (448 aa)
ENSPTRP00000089450annotation not available (303 aa)
ENSPTRP00000089256annotation not available (359 aa)
ENSPTRP00000088766annotation not available (199 aa)
ENSPTRP00000088754annotation not available (350 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)
PHLPP2PHLPP2 isoform 2. (1358 aa)
ENSPTRP00000086358annotation not available (72 aa)
LOC45963814-3-3 protein epsilon-like. (255 aa)
ENSPTRP00000085189annotation not available (1896 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
MDKMidkine (Neurite growth-promoting factor 2). (143 aa)
ENSPTRP00000085036annotation not available (435 aa)
LHX6LHX6 isoform 3. (428 aa)
ENSPTRP00000084830annotation not available (340 aa)
DMD-2Dystrophin. (643 aa)
ENSPTRP00000084287annotation not available (136 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (787 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
GART-2annotation not available (1010 aa)
ENSPTRP00000082446annotation not available (194 aa)
MBOAT7-2Membrane bound O-acyltransferase domain containing 7. (472 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
FAM205AFAM205A isoform 1. (1298 aa)
TMEM14BT0060485 isoform 1. (151 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
ENSPTRP00000080117annotation not available (567 aa)
DCLK2DCLK2 isoform 5. (783 aa)
FEZF2FEZ family zinc finger 2. (463 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
LOC107974864Cytochrome b-c1 complex subunit 8. (82 aa)
DISC1Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
ENSPTRP00000078419annotation not available (329 aa)
ENSPTRP00000078378annotation not available (290 aa)
LOC107971060SRD5A1 isoform 2. (141 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
EFHC1EF-hand domain containing 1. (641 aa)
SLC2A1Solute carrier family 2 (Facilitated glucose transporter), member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
EZH2Enhancer of zeste homolog 2. (754 aa)
UQCRQUbiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa. (82 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (543 aa)
LOC100611979Probable 28S rRNA (cytosine-C(5))-methyltransferase. (448 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SUN1SUN1 isoform 2. (925 aa)
ENSPTRP00000075494annotation not available (194 aa)
NSUN5-2NOP2/Sun domain family, member 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (466 aa)
POU3F3POU domain protein. (476 aa)
ROBO1Roundabout guidance receptor 1. (1684 aa)
NDE1NudE nuclear distribution gene E homolog 1. (359 aa)
PPP1R9BProtein phosphatase 1, regulatory (Inhibitor) subunit 9B. (817 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
NKX2-1NKX2-1 isoform 1. (401 aa)
HTR5A-25-hydroxytryptamine receptor 5A. (357 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
NF2Neurofibromin 2 (Merlin). (595 aa)
ID4Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa)
FOXP2Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (741 aa)
NDEL1-2NudE nuclear distribution gene E homolog-like 1. (351 aa)
ARXARX isoform 1. (559 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ZIC1Zic family member 1. (447 aa)
DMDDMD isoform 3. (3685 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
LAMB1LAMB1 isoform 5. (1789 aa)
ENSPTRP00000068866annotation not available (532 aa)
CDONCell adhesion associated, oncogene regulated. (1286 aa)
ATP1A3ATP1A3 isoform 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1287 aa)
PEX5Peroxisomal biogenesis factor 5. (639 aa)
SYNE2SYNE2 isoform 1. (6907 aa)
PHACTR1Phosphatase and actin regulator. (649 aa)
DCXDCX isoform 5. (420 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
TMEM108Transmembrane protein 108. (575 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC748850HDAC2 isoform 9. (445 aa)
ZIC3Zic family member 3. (466 aa)
PAX6PAX6 isoform 13. (436 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ENSPTRP00000065099annotation not available (337 aa)
ENSPTRP00000065012annotation not available (108 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
TSC1TSC complex subunit 1. (1164 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
FAT4FAT tumor suppressor homolog 4. (4983 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
RELNRELN isoform 3. (3460 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
RTN4Reticulon. (1192 aa)
ADGRG1Adhesion G-protein coupled receptor G1; Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintenance of hematopoietic stem cells a [...] (693 aa)
CSNK2A2Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. (350 aa)
ATOH1Protein atonal homolog 1; Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). (356 aa)
RARARARA isoform 4. (624 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
FOXG1FOXG1 isoform 8. (489 aa)
DAB1DAB adaptor protein 1. (588 aa)
HSD3B2Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. (372 aa)
BCANBCAN isoform 2. (907 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3477 aa)
SRGAP2SRGAP2 isoform 1. (1071 aa)
PROX1Prospero homeobox 1. (737 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PAX5PAX5 isoform 1. (391 aa)
SCTSCT isoform 1. (125 aa)
TENT2PAPD4 isoform 1. (484 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
SUN2Sad1 and UNC84 domain containing 2. (717 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (955 aa)
CRKLV-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa)
TBR1T-box brain transcription factor 1. (682 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa)
XAB2XPA binding protein 2. (855 aa)
DLX1Distal-less homeobox 1. (255 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
LHX2LHX2 isoform 1. (406 aa)
TRAPPC9Trafficking protein particle complex 9. (1246 aa)
TACC1Transforming, acidic coiled-coil containing protein 1. (806 aa)
FUT10Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (481 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
NSUN5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (470 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
NEUROD6Neurogenic differentiation factor. (337 aa)
NPYNeuropeptide Y. (97 aa)
MAS1MAS1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (325 aa)
DIXDC1DIX domain containing 1. (683 aa)
AKIRIN2AKIRIN2 isoform 1. (203 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (423 aa)
CEP120Centrosomal protein 120kDa. (986 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
ANXA3Annexin. (323 aa)
UBA6Ubiquitin-like modifier-activating enzyme 6. (1052 aa)
EPHA5EPH receptor A5. (1038 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (838 aa)
FBXO45F-box protein 45. (286 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
EIF2B5Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa. (721 aa)
RHOARas homolog family member A. (193 aa)
EOMESEOMES isoform 2. (704 aa)
SLC32A1Solute carrier family 32 member 1. (525 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
BTBD3BTB (POZ) domain containing 3. (522 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
CCDC141Coiled-coil domain containing 141. (955 aa)
DLX2Distal-less homeobox 2. (328 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
ALKTyrosine-protein kinase receptor. (1620 aa)
WDR62WDR62 isoform 2. (1523 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1948 aa)
SEMA6BSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family. (888 aa)
NARS1Asparaginyl-tRNA synthetase, cytoplasmic. (558 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
NF1Neurofibromin 1. (2839 aa)
NDEL1NudE nuclear distribution gene E homolog-like 1. (345 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Belongs to the 14-3-3 family. (255 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
BMERB1Uncharacterized protein C16orf45 homolog. (204 aa)
IGF1RTyrosine-protein kinase receptor. (1364 aa)
CCDC85CCoiled-coil domain containing 85C. (419 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
MPP5Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (675 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
LHX5LHX5 isoform 2. (402 aa)
KCNA1Potassium voltage-gated channel, shaker-related subfamily, member 1 (Episodic ataxia with myokymia); Belongs to the potassium channel family. (495 aa)
FEZ1Fasciculation and elongation protein zeta 1 (Zygin I). (392 aa)
H2AFXH2AFX isoform 1. (143 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
THTyrosine hydroxylase. (528 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
TACC2Transforming acidic coiled-coil containing protein 2. (1094 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
ZMIZ1Zinc finger, MIZ-type containing 1. (1073 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
HSD3B1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa)
LRP8LDL receptor related protein 8. (960 aa)
DMRTA2DMRT like family A2. (539 aa)
HTR65-hydroxytryptamine receptor 6; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (By similarity). (440 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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