STRINGSTRING
CHRNB2 CHRNB2 ATOH7 ATOH7 TCIRG1 TCIRG1 TMEM126A TMEM126A NKX2-2 NKX2-2 SLC25A46 SLC25A46 GLI3 GLI3 EXT1 EXT1 EPHB2 EPHB2 EPHB1 EPHB1 ENSPTRP00000062542 ENSPTRP00000062542 LPAR1 LPAR1 RPL24 RPL24 ENSPTRP00000083623 ENSPTRP00000083623 ENSPTRP00000088146 ENSPTRP00000088146 ENSPTRP00000088795 ENSPTRP00000088795 NAV2 NAV2 PAX2 PAX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHRNB2CHRNB2 isoform 2. (502 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
TMEM126ATransmembrane protein 126A. (195 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
SLC25A46Solute carrier family 25, member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
EPHB2EPH receptor B2. (1055 aa)
EPHB1EPH receptor B1. (984 aa)
ENSPTRP00000062542annotation not available (147 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
RPL24RPL24 isoform 1. (157 aa)
ENSPTRP00000083623annotation not available (133 aa)
ENSPTRP00000088146annotation not available (157 aa)
ENSPTRP00000088795annotation not available (62 aa)
NAV2Neuron navigator 2. (2488 aa)
PAX2PAX2 isoform 1. (417 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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