STRINGSTRING
AGTPBP1 AGTPBP1 GNPAT GNPAT ENSPTRP00000092702 ENSPTRP00000092702 ENSPTRP00000092364 ENSPTRP00000092364 TRNP1 TRNP1 OPHN1 OPHN1 ZNF365 ZNF365 RORA RORA GRID2 GRID2 ENSPTRP00000081136 ENSPTRP00000081136 CDK5 CDK5 GLI1 GLI1 ENSPTRP00000077211 ENSPTRP00000077211 ENSPTRP00000074763 ENSPTRP00000074763 PTPN11-2 PTPN11-2 NRXN1 NRXN1 ABL1 ABL1 WHRN WHRN SMO-2 SMO-2 ENSPTRP00000067174 ENSPTRP00000067174 WNT7A WNT7A ATP7A ATP7A LOC100609513 LOC100609513 CK820_G0012168 CK820_G0012168 PTPN11 PTPN11 LHX1 LHX1 DAB1 DAB1 PROX1 PROX1 CEND1 CEND1 MTPN MTPN COQ8B COQ8B SPTBN2 SPTBN2 GLI2 GLI2 LDB1 LDB1 SMO SMO DLL1 DLL1 SLC25A46 SLC25A46 TTLL1 TTLL1 CBS CBS SERPINE2 SERPINE2 TTC21B TTC21B CBLN1 CBLN1 HERC1 HERC1 LHX5 LHX5 FAIM2 FAIM2 WNT1 WNT1 KNDC1 KNDC1 KIF14 KIF14 HSPA5 HSPA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGTPBP1ATP/GTP binding protein 1. (1290 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (691 aa)
ENSPTRP00000092702annotation not available (482 aa)
ENSPTRP00000092364annotation not available (574 aa)
TRNP1TMF1-regulated nuclear protein 1. (227 aa)
OPHN1Oligophrenin-1; Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at pre- synaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity). (810 aa)
ZNF365Zinc finger protein 365. (407 aa)
RORARAR-related orphan receptor A. (555 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
ENSPTRP00000081136LOW QUALITY PROTEIN: uncharacterized protein LOC100614654. (148 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
GLI1GLI family zinc finger 1. (1106 aa)
ENSPTRP00000077211annotation not available (269 aa)
ENSPTRP00000074763annotation not available (520 aa)
PTPN11-2Protein tyrosine phosphatase non-receptor type 11. (579 aa)
NRXN1NRXN1 isoform 9. (1547 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
WHRNWHRN isoform 2. (907 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
ENSPTRP00000067174annotation not available (502 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
ATP7AATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
LOC10060951378 kDa glucose-regulated protein pseudogene. (617 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
DAB1DAB adaptor protein 1. (588 aa)
PROX1Prospero homeobox 1. (737 aa)
CEND1Cell cycle exit and neuronal differentiation 1. (149 aa)
MTPNMTPN isoform 1. (118 aa)
COQ8BAarF domain containing kinase 4. (544 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
GLI2GLI family zinc finger 2. (1587 aa)
LDB1LIM domain binding 1. (411 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SLC25A46Solute carrier family 25, member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
TTLL1Tubulin tyrosine ligase-like family, member 1. (404 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (551 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
HERC1Hect (Homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1. (4861 aa)
LHX5LHX5 isoform 2. (402 aa)
FAIM2FAIM2 isoform 2; Belongs to the BI1 family. (316 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
KNDC1KNDC1 isoform 1. (1672 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
HSPA5Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family. (654 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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