33 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATP8B3	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1301 aa)
	PAX2	PAX2 isoform 1. (417 aa)
	PLXNA1	PLXNA1 isoform 1. (1915 aa)
	TFAP2A	Transcription factor AP-2 alpha. (439 aa)
	HOXD3	HOXD3 isoform 3. (432 aa)
	DMD-2	Dystrophin. (643 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	SEMA3F	SEMA3F isoform 2; Belongs to the semaphorin family. (785 aa)
	HOXA1-2	Homeobox A1. (335 aa)
	DCANP1	LOW QUALITY PROTEIN: dendritic cell nuclear protein 1. (237 aa)
	TIFAB	TIFAB isoform 1. (161 aa)
	HOXA3-2	Homeobox A3. (443 aa)
	DMD	DMD isoform 3. (3685 aa)
	ATP8B1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
	HOXA3	HOXA3 isoform 3. (443 aa)
	HOXB3	HOXB3 isoform 13. (431 aa)
	PLXNA4	PLXNA4 isoform 1. (1894 aa)
	EPHB1	EPH receptor B1. (984 aa)
	EPHB2	EPH receptor B2. (1055 aa)
	MAFB	V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (Avian). (323 aa)
	PHOX2A	Paired like homeobox 2A. (284 aa)
	PLXNA3	PLXNA3 isoform 1. (1871 aa)
	GLI3	Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
	HOXA1	HOXA1 isoform 2. (335 aa)
	NEUROG1	NEUROG1 isoform 1. (237 aa)
	TBX1	TBX1 isoform 1. (478 aa)
	ADARB1	ADARB1 isoform 13. (741 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	HOXB2	HOXB2 isoform 1. (356 aa)
	HOXB1	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily. (301 aa)
	EGR2	Early growth response 2. (476 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	CHRNB2	CHRNB2 isoform 2. (502 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CITED2	TFAP2A	ENSPTRP00000081552	ENSPTRP00000087495	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 alpha.	0.890
EGR2	HOXB1	ENSPTRP00000004374	ENSPTRP00000015899	Early growth response 2.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.579
EGR2	HOXB2	ENSPTRP00000004374	ENSPTRP00000015901	Early growth response 2.	HOXB2 isoform 1.	0.581
EGR2	MAFB	ENSPTRP00000004374	ENSPTRP00000052159	Early growth response 2.	V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (Avian).	0.428
EPHB2	PLXNA1	ENSPTRP00000052704	ENSPTRP00000088978	EPH receptor B2.	PLXNA1 isoform 1.	0.430
EPHB2	SEMA3F	ENSPTRP00000052704	ENSPTRP00000079897	EPH receptor B2.	SEMA3F isoform 2; Belongs to the semaphorin family.	0.491
HOXA1	HOXB1	ENSPTRP00000032489	ENSPTRP00000015899	HOXA1 isoform 2.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.928
HOXA3	HOXB2	ENSPTRP00000067513	ENSPTRP00000015901	HOXA3 isoform 3.	HOXB2 isoform 1.	0.403
HOXA3-2	HOXB2	ENSPTRP00000070439	ENSPTRP00000015901	Homeobox A3.	HOXB2 isoform 1.	0.403
HOXB1	EGR2	ENSPTRP00000015899	ENSPTRP00000004374	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	Early growth response 2.	0.579
HOXB1	HOXA1	ENSPTRP00000015899	ENSPTRP00000032489	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	HOXA1 isoform 2.	0.928
HOXB1	HOXB2	ENSPTRP00000015899	ENSPTRP00000015901	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	HOXB2 isoform 1.	0.576
HOXB1	HOXB3	ENSPTRP00000015899	ENSPTRP00000063008	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	HOXB3 isoform 13.	0.419
HOXB1	TBX1	ENSPTRP00000015899	ENSPTRP00000024223	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	TBX1 isoform 1.	0.439
HOXB2	EGR2	ENSPTRP00000015901	ENSPTRP00000004374	HOXB2 isoform 1.	Early growth response 2.	0.581
HOXB2	HOXA3	ENSPTRP00000015901	ENSPTRP00000067513	HOXB2 isoform 1.	HOXA3 isoform 3.	0.403
HOXB2	HOXA3-2	ENSPTRP00000015901	ENSPTRP00000070439	HOXB2 isoform 1.	Homeobox A3.	0.403
HOXB2	HOXB1	ENSPTRP00000015901	ENSPTRP00000015899	HOXB2 isoform 1.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.576
HOXB2	HOXB3	ENSPTRP00000015901	ENSPTRP00000063008	HOXB2 isoform 1.	HOXB3 isoform 13.	0.628
HOXB3	HOXB1	ENSPTRP00000063008	ENSPTRP00000015899	HOXB3 isoform 13.	Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily.	0.419