28 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOXP2	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (741 aa)
	FOXP1	FOXP1 isoform 2. (693 aa)
	SECISBP2	SECIS binding protein 2. (855 aa)
	ENSPTRP00000078003	annotation not available (847 aa)
	BBS4	Bardet-Biedl syndrome 4. (519 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (894 aa)
	OGDH	Oxoglutarate dehydrogenase. (1038 aa)
	ZSWIM6	ZSWIM6 isoform 1. (1022 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (721 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	SLITRK5	SLIT and NTRK like family member 5. (958 aa)
	LRRK2	Leucine-rich repeat kinase 2. (2527 aa)
	BBS1	Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
	ZSWIM5	Zinc finger SWIM-type containing 5. (1185 aa)
	JAKMIP1-2	Janus kinase and microtubule interacting protein 1. (831 aa)
	ENSPTRP00000080117	annotation not available (567 aa)
	FAM205A	FAM205A isoform 1. (1298 aa)
	RARB	Retinoic acid receptor, beta. (448 aa)
	HPRT1	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (218 aa)
	INHBA	Inhibin subunit beta A. (426 aa)
	ENSPTRP00000063424	annotation not available (1563 aa)
	SHANK3	SHANK3 isoform 2. (1744 aa)
	CNTNAP2	Contactin associated protein like 2. (1331 aa)
	ENSPTRP00000065012	annotation not available (108 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	SLC7A11	Solute carrier family 7, (Cationic amino acid transporter, y+ system) member 11. (515 aa)
	ZSWIM4	Zinc finger, SWIM-type containing 4. (932 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A3	RARB	ENSPTRP00000012824	ENSPTRP00000082886	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Retinoic acid receptor, beta.	0.490
BBS1	BBS2	ENSPTRP00000006768	ENSPTRP00000013880	Bardet-Biedl syndrome 1 protein isoform X1.	Bardet-Biedl syndrome 2 protein homolog.	0.999
BBS1	BBS4	ENSPTRP00000006768	ENSPTRP00000057396	Bardet-Biedl syndrome 1 protein isoform X1.	Bardet-Biedl syndrome 4.	0.999
BBS1	MKKS	ENSPTRP00000006768	ENSPTRP00000022725	Bardet-Biedl syndrome 1 protein isoform X1.	McKusick-Kaufman syndrome.	0.421
BBS2	BBS1	ENSPTRP00000013880	ENSPTRP00000006768	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 1 protein isoform X1.	0.999
BBS2	BBS4	ENSPTRP00000013880	ENSPTRP00000057396	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 4.	0.999
BBS2	MKKS	ENSPTRP00000013880	ENSPTRP00000022725	Bardet-Biedl syndrome 2 protein homolog.	McKusick-Kaufman syndrome.	0.527
BBS4	BBS1	ENSPTRP00000057396	ENSPTRP00000006768	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1 protein isoform X1.	0.999
BBS4	BBS2	ENSPTRP00000057396	ENSPTRP00000013880	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2 protein homolog.	0.999
BCL11B	FOXP2	ENSPTRP00000052505	ENSPTRP00000071606	BAF chromatin remodeling complex subunit BCL11B.	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.480
CNTNAP2	ENSPTRP00000063424	ENSPTRP00000064715	ENSPTRP00000063424	Contactin associated protein like 2.	annotation not available	0.428
CNTNAP2	FOXP1	ENSPTRP00000064715	ENSPTRP00000075187	Contactin associated protein like 2.	FOXP1 isoform 2.	0.693
CNTNAP2	FOXP2	ENSPTRP00000064715	ENSPTRP00000071606	Contactin associated protein like 2.	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.875
CNTNAP2	SHANK3	ENSPTRP00000064715	ENSPTRP00000063533	Contactin associated protein like 2.	SHANK3 isoform 2.	0.525
ENSPTRP00000063424	CNTNAP2	ENSPTRP00000063424	ENSPTRP00000064715	annotation not available	Contactin associated protein like 2.	0.428
ENSPTRP00000063424	ENSPTRP00000065012	ENSPTRP00000063424	ENSPTRP00000065012	annotation not available	annotation not available	0.428
ENSPTRP00000065012	ENSPTRP00000063424	ENSPTRP00000065012	ENSPTRP00000063424	annotation not available	annotation not available	0.428
ENSPTRP00000065012	FOXP2	ENSPTRP00000065012	ENSPTRP00000071606	annotation not available	Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).	0.642
ENSPTRP00000065012	SHANK3	ENSPTRP00000065012	ENSPTRP00000063533	annotation not available	SHANK3 isoform 2.	0.428
ENSPTRP00000078003	OGDH	ENSPTRP00000078003	ENSPTRP00000032714	annotation not available	Oxoglutarate dehydrogenase.	0.543