14 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GCM1	Glial cells missing transcription factor 1. (436 aa)
	NKX2-2	NKX2-2 isoform 1. (273 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	SOX8	SOX8 isoform 1. (446 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
	NRG1	NRG1 isoform 3. (713 aa)
	HES5-2	Hes family bHLH transcription factor 5. (165 aa)
	ENSPTRP00000079007	annotation not available (323 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (232 aa)
	OLIG2	OLIG2 isoform 1. (323 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	SOX2	SRY-box transcription factor 2. (319 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	HES5	Hes family bHLH transcription factor 5. (165 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	ENSPTRP00000079007	ENSPTRP00000077846	ENSPTRP00000079007	Achaete-scute family bHLH transcription factor 1.	annotation not available	0.487
ASCL1	HES5	ENSPTRP00000077846	ENSPTRP00000040760	Achaete-scute family bHLH transcription factor 1.	Hes family bHLH transcription factor 5.	0.490
ASCL1	HES5-2	ENSPTRP00000077846	ENSPTRP00000080637	Achaete-scute family bHLH transcription factor 1.	Hes family bHLH transcription factor 5.	0.490
ASCL1	NKX2-2	ENSPTRP00000077846	ENSPTRP00000022825	Achaete-scute family bHLH transcription factor 1.	NKX2-2 isoform 1.	0.685
ASCL1	OLIG2	ENSPTRP00000077846	ENSPTRP00000069533	Achaete-scute family bHLH transcription factor 1.	OLIG2 isoform 1.	0.578
ASCL1	PAX6	ENSPTRP00000077846	ENSPTRP00000065705	Achaete-scute family bHLH transcription factor 1.	PAX6 isoform 13.	0.590
ASCL1	SOX2	ENSPTRP00000077846	ENSPTRP00000046752	Achaete-scute family bHLH transcription factor 1.	SRY-box transcription factor 2.	0.562
CTNNB1	PAX6	ENSPTRP00000044466	ENSPTRP00000065705	Catenin (Cadherin-associated protein), beta 1, 88kDa.	PAX6 isoform 13.	0.469
CTNNB1	SOX2	ENSPTRP00000044466	ENSPTRP00000046752	Catenin (Cadherin-associated protein), beta 1, 88kDa.	SRY-box transcription factor 2.	0.897
CTNNB1	SOX8	ENSPTRP00000044466	ENSPTRP00000012939	Catenin (Cadherin-associated protein), beta 1, 88kDa.	SOX8 isoform 1.	0.559
CTNNB1	SOX9	ENSPTRP00000044466	ENSPTRP00000016293	Catenin (Cadherin-associated protein), beta 1, 88kDa.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.859
ENSPTRP00000079007	ASCL1	ENSPTRP00000079007	ENSPTRP00000077846	annotation not available	Achaete-scute family bHLH transcription factor 1.	0.487
ENSPTRP00000079007	NKX2-2	ENSPTRP00000079007	ENSPTRP00000022825	annotation not available	NKX2-2 isoform 1.	0.620
ENSPTRP00000079007	PAX6	ENSPTRP00000079007	ENSPTRP00000065705	annotation not available	PAX6 isoform 13.	0.578
ENSPTRP00000079007	SOX2	ENSPTRP00000079007	ENSPTRP00000046752	annotation not available	SRY-box transcription factor 2.	0.492
ENSPTRP00000079007	SOX8	ENSPTRP00000079007	ENSPTRP00000012939	annotation not available	SOX8 isoform 1.	0.402
HES5	ASCL1	ENSPTRP00000040760	ENSPTRP00000077846	Hes family bHLH transcription factor 5.	Achaete-scute family bHLH transcription factor 1.	0.490
HES5	PAX6	ENSPTRP00000040760	ENSPTRP00000065705	Hes family bHLH transcription factor 5.	PAX6 isoform 13.	0.470
HES5	SOX2	ENSPTRP00000040760	ENSPTRP00000046752	Hes family bHLH transcription factor 5.	SRY-box transcription factor 2.	0.468
HES5-2	ASCL1	ENSPTRP00000080637	ENSPTRP00000077846	Hes family bHLH transcription factor 5.	Achaete-scute family bHLH transcription factor 1.	0.490