20 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OLIG2	OLIG2 isoform 1. (323 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	UQCRQ	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa. (82 aa)
	ENSPTRP00000078003	annotation not available (847 aa)
	LOC107971060	SRD5A1 isoform 2. (141 aa)
	ENSPTRP00000079007	annotation not available (323 aa)
	LOC107974864	Cytochrome b-c1 complex subunit 8. (82 aa)
	ENSPTRP00000086358	annotation not available (72 aa)
	CHRNB2	CHRNB2 isoform 2. (502 aa)
	FOXB1	FOXB1 isoform 3. (325 aa)
	GBX2	Gastrulation brain homeobox 2. (348 aa)
	SRD5A1	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
	PTCHD4	Patched domain containing 4. (846 aa)
	OGDH	Oxoglutarate dehydrogenase. (1038 aa)
	SMO	SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
	TAL2	TAL bHLH transcription factor 2. (108 aa)
	PTCHD1	Patched domain containing 1. (888 aa)
	CNTNAP2	Contactin associated protein like 2. (1331 aa)
	ENSPTRP00000065012	annotation not available (108 aa)
	SMO-2	Smoothened, frizzled class receptor. (786 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTNAP2	PTCHD1	ENSPTRP00000064715	ENSPTRP00000037271	Contactin associated protein like 2.	Patched domain containing 1.	0.488
ENSPTRP00000065012	PTCHD1	ENSPTRP00000065012	ENSPTRP00000037271	annotation not available	Patched domain containing 1.	0.488
ENSPTRP00000078003	OGDH	ENSPTRP00000078003	ENSPTRP00000032714	annotation not available	Oxoglutarate dehydrogenase.	0.543
ENSPTRP00000079007	SHH	ENSPTRP00000079007	ENSPTRP00000075730	annotation not available	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.404
ENSPTRP00000079007	TAL2	ENSPTRP00000079007	ENSPTRP00000036263	annotation not available	TAL bHLH transcription factor 2.	0.483
ENSPTRP00000086358	LOC107974864	ENSPTRP00000086358	ENSPTRP00000079731	annotation not available	Cytochrome b-c1 complex subunit 8.	0.546
ENSPTRP00000086358	UQCRQ	ENSPTRP00000086358	ENSPTRP00000076713	annotation not available	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa.	0.546
GBX2	SHH	ENSPTRP00000022357	ENSPTRP00000075730	Gastrulation brain homeobox 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.563
LOC107974864	ENSPTRP00000086358	ENSPTRP00000079731	ENSPTRP00000086358	Cytochrome b-c1 complex subunit 8.	annotation not available	0.546
LOC107974864	UQCRQ	ENSPTRP00000079731	ENSPTRP00000076713	Cytochrome b-c1 complex subunit 8.	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa.	0.544
OGDH	ENSPTRP00000078003	ENSPTRP00000032714	ENSPTRP00000078003	Oxoglutarate dehydrogenase.	annotation not available	0.543
OLIG2	SHH	ENSPTRP00000069533	ENSPTRP00000075730	OLIG2 isoform 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.536
OLIG2	TAL2	ENSPTRP00000069533	ENSPTRP00000036263	OLIG2 isoform 1.	TAL bHLH transcription factor 2.	0.483
PTCHD1	CNTNAP2	ENSPTRP00000037271	ENSPTRP00000064715	Patched domain containing 1.	Contactin associated protein like 2.	0.488
PTCHD1	ENSPTRP00000065012	ENSPTRP00000037271	ENSPTRP00000065012	Patched domain containing 1.	annotation not available	0.488
PTCHD1	SHH	ENSPTRP00000037271	ENSPTRP00000075730	Patched domain containing 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.607
SHH	ENSPTRP00000079007	ENSPTRP00000075730	ENSPTRP00000079007	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	annotation not available	0.404
SHH	GBX2	ENSPTRP00000075730	ENSPTRP00000022357	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Gastrulation brain homeobox 2.	0.563
SHH	OLIG2	ENSPTRP00000075730	ENSPTRP00000069533	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	OLIG2 isoform 1.	0.536
SHH	PTCHD1	ENSPTRP00000075730	ENSPTRP00000037271	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched domain containing 1.	0.607