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TTC21B | Tetratricopeptide repeat domain 21B. (1316 aa) | ||||
SIX3 | SIX homeobox 3. (331 aa) | ||||
PAX6 | PAX6 isoform 13. (436 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) | ||||
NKX2-1 | NKX2-1 isoform 1. (401 aa) | ||||
GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa) | ||||
GSX2 | GSX2 isoform 2. (304 aa) |