STRINGSTRING
ZSWIM5 ZSWIM5 NRP1 NRP1 BCL11B BCL11B ASPM ASPM WNT3A WNT3A TBR1 TBR1 HES5 HES5 DLX1 DLX1 PLXNA3 PLXNA3 OGDH OGDH ENSPTRP00000086358 ENSPTRP00000086358 GLI3 GLI3 OTP OTP ZSWIM6 ZSWIM6 FOXG1 FOXG1 GATA2 GATA2 POU3F4 POU3F4 SOX1 SOX1 ENSPTRP00000063424 ENSPTRP00000063424 SHANK3 SHANK3 HES1 HES1 ATP7A ATP7A PAX6 PAX6 SEMA3E SEMA3E DCX DCX ENSPTRP00000068492 ENSPTRP00000068492 ZSWIM4 ZSWIM4 LHX8 LHX8 NKX2-1 NKX2-1 NR2E1 NR2E1 SECISBP2 SECISBP2 UQCRQ UQCRQ SLC4A10 SLC4A10 ASCL1 ASCL1 ENSPTRP00000078003 ENSPTRP00000078003 SCYL2 SCYL2 DISC1 DISC1 RAPGEF2 RAPGEF2 LOC107974864 LOC107974864 LEF1 LEF1 FEZF2 FEZF2 DCLK2 DCLK2 DCT DCT HES5-2 HES5-2 CSF1R CSF1R NHLH2 NHLH2 LHX6 LHX6 NR2E1-2 NR2E1-2 NDNF NDNF INHBA INHBA METTL14 METTL14 RHOA RHOA GBX2 GBX2 NRP2 NRP2 DLX2 DLX2 METTL3 METTL3 LHX5 LHX5 ZMIZ1 ZMIZ1 PLXNA1 PLXNA1 FGFR2 FGFR2 CK820_G0016130 CK820_G0016130
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZSWIM5Zinc finger SWIM-type containing 5. (1185 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3477 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TBR1T-box brain transcription factor 1. (682 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
DLX1Distal-less homeobox 1. (255 aa)
PLXNA3PLXNA3 isoform 1. (1871 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
ENSPTRP00000086358annotation not available (72 aa)
GLI3Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa)
OTPOrthopedia homeobox. (325 aa)
ZSWIM6ZSWIM6 isoform 1. (1022 aa)
FOXG1FOXG1 isoform 8. (489 aa)
GATA2GATA binding protein 2. (480 aa)
POU3F4POU domain protein. (361 aa)
SOX1SOX1 isoform 1. (391 aa)
ENSPTRP00000063424annotation not available (1563 aa)
SHANK3SHANK3 isoform 2. (1744 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ATP7AATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
PAX6PAX6 isoform 13. (436 aa)
SEMA3ESEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
DCXDCX isoform 5. (420 aa)
ENSPTRP00000068492annotation not available (777 aa)
ZSWIM4Zinc finger, SWIM-type containing 4. (932 aa)
LHX8LHX8 isoform 2. (377 aa)
NKX2-1NKX2-1 isoform 1. (401 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
SECISBP2SECIS binding protein 2. (855 aa)
UQCRQUbiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa. (82 aa)
SLC4A10Anion exchange protein. (1138 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
ENSPTRP00000078003annotation not available (847 aa)
SCYL2SCYL2 isoform 1. (962 aa)
DISC1Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
RAPGEF2RAPGEF2 isoform 2. (1701 aa)
LOC107974864Cytochrome b-c1 complex subunit 8. (82 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
FEZF2FEZ family zinc finger 2. (463 aa)
DCLK2DCLK2 isoform 5. (783 aa)
DCTDopachrome tautomerase. (552 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
LHX6LHX6 isoform 3. (428 aa)
NR2E1-2Nuclear receptor subfamily 2 group E member 1. (385 aa)
NDNFNDNF isoform 1. (568 aa)
INHBAInhibin subunit beta A. (426 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
RHOARas homolog family member A. (193 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
DLX2Distal-less homeobox 2. (328 aa)
METTL3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
LHX5LHX5 isoform 2. (402 aa)
ZMIZ1Zinc finger, MIZ-type containing 1. (1073 aa)
PLXNA1PLXNA1 isoform 1. (1915 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
CK820_G0016130SCYL2 isoform 5. (871 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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