48 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCYL2	SCYL2 isoform 1. (962 aa)
	DISC1	Disrupted in schizophrenia 1 protein isoform X1. (977 aa)
	RAPGEF2	RAPGEF2 isoform 2. (1701 aa)
	LOC107974864	Cytochrome b-c1 complex subunit 8. (82 aa)
	FEZF2	FEZ family zinc finger 2. (463 aa)
	DCLK2	DCLK2 isoform 5. (783 aa)
	CSF1R	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
	NHLH2	Nescient helix-loop-helix 2. (135 aa)
	LHX6	LHX6 isoform 3. (428 aa)
	ENSPTRP00000086358	annotation not available (72 aa)
	PLXNA1	PLXNA1 isoform 1. (1915 aa)
	NDNF	NDNF isoform 1. (568 aa)
	INHBA	Inhibin subunit beta A. (426 aa)
	ZSWIM5	Zinc finger SWIM-type containing 5. (1185 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	ZMIZ1	Zinc finger, MIZ-type containing 1. (1073 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	CK820_G0016130	SCYL2 isoform 5. (871 aa)
	LHX5	LHX5 isoform 2. (402 aa)
	DLX2	Distal-less homeobox 2. (328 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	GBX2	Gastrulation brain homeobox 2. (348 aa)
	ZSWIM6	ZSWIM6 isoform 1. (1022 aa)
	OTP	Orthopedia homeobox. (325 aa)
	OGDH	Oxoglutarate dehydrogenase. (1038 aa)
	PLXNA3	PLXNA3 isoform 1. (1871 aa)
	DLX1	Distal-less homeobox 1. (255 aa)
	TBR1	T-box brain transcription factor 1. (682 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (894 aa)
	FOXG1	FOXG1 isoform 8. (489 aa)
	GATA2	GATA binding protein 2. (480 aa)
	POU3F4	POU domain protein. (361 aa)
	SOX1	SOX1 isoform 1. (391 aa)
	ENSPTRP00000063424	annotation not available (1563 aa)
	SHANK3	SHANK3 isoform 2. (1744 aa)
	ATP7A	ATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	SEMA3E	SEMA3E isoform 1; Belongs to the semaphorin family. (775 aa)
	DCX	DCX isoform 5. (420 aa)
	ENSPTRP00000068492	annotation not available (777 aa)
	ZSWIM4	Zinc finger, SWIM-type containing 4. (932 aa)
	LHX8	LHX8 isoform 2. (377 aa)
	NKX2-1	NKX2-1 isoform 1. (401 aa)
	SECISBP2	SECIS binding protein 2. (855 aa)
	UQCRQ	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa. (82 aa)
	SLC4A10	Anion exchange protein. (1138 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (232 aa)
	ENSPTRP00000078003	annotation not available (847 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	DCX	ENSPTRP00000077846	ENSPTRP00000067534	Achaete-scute family bHLH transcription factor 1.	DCX isoform 5.	0.497
ASCL1	DLX1	ENSPTRP00000077846	ENSPTRP00000039172	Achaete-scute family bHLH transcription factor 1.	Distal-less homeobox 1.	0.688
ASCL1	DLX2	ENSPTRP00000077846	ENSPTRP00000021601	Achaete-scute family bHLH transcription factor 1.	Distal-less homeobox 2.	0.808
ASCL1	FOXG1	ENSPTRP00000077846	ENSPTRP00000052740	Achaete-scute family bHLH transcription factor 1.	FOXG1 isoform 8.	0.635
ASCL1	GATA2	ENSPTRP00000077846	ENSPTRP00000054198	Achaete-scute family bHLH transcription factor 1.	GATA binding protein 2.	0.436
ASCL1	LHX6	ENSPTRP00000077846	ENSPTRP00000085026	Achaete-scute family bHLH transcription factor 1.	LHX6 isoform 3.	0.547
ASCL1	LHX8	ENSPTRP00000077846	ENSPTRP00000072266	Achaete-scute family bHLH transcription factor 1.	LHX8 isoform 2.	0.476
ASCL1	NKX2-1	ENSPTRP00000077846	ENSPTRP00000072897	Achaete-scute family bHLH transcription factor 1.	NKX2-1 isoform 1.	0.549
ASCL1	PAX6	ENSPTRP00000077846	ENSPTRP00000065705	Achaete-scute family bHLH transcription factor 1.	PAX6 isoform 13.	0.590
ASCL1	SOX1	ENSPTRP00000077846	ENSPTRP00000061108	Achaete-scute family bHLH transcription factor 1.	SOX1 isoform 1.	0.465
ASCL1	TBR1	ENSPTRP00000077846	ENSPTRP00000046292	Achaete-scute family bHLH transcription factor 1.	T-box brain transcription factor 1.	0.473
BCL11B	DLX1	ENSPTRP00000052505	ENSPTRP00000039172	BAF chromatin remodeling complex subunit BCL11B.	Distal-less homeobox 1.	0.406
BCL11B	FOXG1	ENSPTRP00000052505	ENSPTRP00000052740	BAF chromatin remodeling complex subunit BCL11B.	FOXG1 isoform 8.	0.562
BCL11B	PAX6	ENSPTRP00000052505	ENSPTRP00000065705	BAF chromatin remodeling complex subunit BCL11B.	PAX6 isoform 13.	0.584
BCL11B	TBR1	ENSPTRP00000052505	ENSPTRP00000046292	BAF chromatin remodeling complex subunit BCL11B.	T-box brain transcription factor 1.	0.756
DCX	ASCL1	ENSPTRP00000067534	ENSPTRP00000077846	DCX isoform 5.	Achaete-scute family bHLH transcription factor 1.	0.497
DCX	PAX6	ENSPTRP00000067534	ENSPTRP00000065705	DCX isoform 5.	PAX6 isoform 13.	0.520
DCX	TBR1	ENSPTRP00000067534	ENSPTRP00000046292	DCX isoform 5.	T-box brain transcription factor 1.	0.482
DISC1	FEZF2	ENSPTRP00000078918	ENSPTRP00000079962	Disrupted in schizophrenia 1 protein isoform X1.	FEZ family zinc finger 2.	0.619
DLX1	ASCL1	ENSPTRP00000039172	ENSPTRP00000077846	Distal-less homeobox 1.	Achaete-scute family bHLH transcription factor 1.	0.688