15 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX17	SOX17 isoform 1. (416 aa)
	GBX2	Gastrulation brain homeobox 2. (348 aa)
	KDM2B	Lysine (K)-specific demethylase 2B. (1336 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	SSBP3	Single stranded DNA binding protein 3. (388 aa)
	ENSPTRP00000087502	annotation not available (347 aa)
	ENSPTRP00000086171	annotation not available (421 aa)
	ENSPTRP00000085013	annotation not available (166 aa)
	LOC737148	Single-stranded DNA-binding protein 3 pseudogene. (331 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	PAX6	PAX6 isoform 13. (436 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	ENSPTRP00000061866	annotation not available (267 aa)
	EN1	Homeobox protein engrailed-like. (396 aa)
	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2. (350 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EN1	FGF8	ENSPTRP00000049224	ENSPTRP00000075677	Homeobox protein engrailed-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.572
EN1	PAX6	ENSPTRP00000049224	ENSPTRP00000065705	Homeobox protein engrailed-like.	PAX6 isoform 13.	0.542
EN1	WNT1	ENSPTRP00000049224	ENSPTRP00000008364	Homeobox protein engrailed-like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.576
FGF8	EN1	ENSPTRP00000075677	ENSPTRP00000049224	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein engrailed-like.	0.572
FGF8	GBX2	ENSPTRP00000075677	ENSPTRP00000022357	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Gastrulation brain homeobox 2.	0.634
FGF8	PAX6	ENSPTRP00000075677	ENSPTRP00000065705	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	PAX6 isoform 13.	0.538
FGF8	WNT1	ENSPTRP00000075677	ENSPTRP00000008364	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.579
GBX2	FGF8	ENSPTRP00000022357	ENSPTRP00000075677	Gastrulation brain homeobox 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.634
GBX2	WNT1	ENSPTRP00000022357	ENSPTRP00000008364	Gastrulation brain homeobox 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.682
PAX6	EN1	ENSPTRP00000065705	ENSPTRP00000049224	PAX6 isoform 13.	Homeobox protein engrailed-like.	0.542
PAX6	FGF8	ENSPTRP00000065705	ENSPTRP00000075677	PAX6 isoform 13.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.538
PAX6	SOX17	ENSPTRP00000065705	ENSPTRP00000034688	PAX6 isoform 13.	SOX17 isoform 1.	0.649
PAX6	WNT1	ENSPTRP00000065705	ENSPTRP00000008364	PAX6 isoform 13.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.411
SOX17	PAX6	ENSPTRP00000034688	ENSPTRP00000065705	SOX17 isoform 1.	PAX6 isoform 13.	0.649
SOX17	WNT1	ENSPTRP00000034688	ENSPTRP00000008364	SOX17 isoform 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.415
WNT1	EN1	ENSPTRP00000008364	ENSPTRP00000049224	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Homeobox protein engrailed-like.	0.576
WNT1	FGF8	ENSPTRP00000008364	ENSPTRP00000075677	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.579
WNT1	GBX2	ENSPTRP00000008364	ENSPTRP00000022357	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Gastrulation brain homeobox 2.	0.682
WNT1	PAX6	ENSPTRP00000008364	ENSPTRP00000065705	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	PAX6 isoform 13.	0.411
WNT1	SOX17	ENSPTRP00000008364	ENSPTRP00000034688	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	SOX17 isoform 1.	0.415