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| | CDK20 | Cyclin-dependent kinase 20; Belongs to the protein kinase superfamily. (376 aa) |
| | MIB1 | Mindbomb E3 ubiquitin protein ligase 1. (1014 aa) |
| | ENSPTRP00000093474 | Cadherin EGF LAG seven-pass G-type receptor 1. (124 aa) |
| | SCRIB-2 | Scribbled homolog. (1662 aa) |
| | FZD1-2 | Frizzled class receptor 1. (580 aa) |
| | TBC1D32 | TBC1D32 isoform 4. (1298 aa) |
| | OVOL2 | Ovo like zinc finger 2. (275 aa) |
| | ENSPTRP00000092218 | annotation not available (738 aa) |
| | ENSPTRP00000091667 | annotation not available (191 aa) |
| | VASP | Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa) |
| | PAX2 | PAX2 isoform 1. (417 aa) |
| | SOX11 | Transcription factor SOX. (441 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (862 aa) |
| | ENSPTRP00000089747 | annotation not available (156 aa) |
| | BRD2 | Bromodomain containing 2. (835 aa) |
| | DCHS1 | DCHS1 isoform 1. (3298 aa) |
| | ENSPTRP00000088582 | annotation not available (66 aa) |
| | PRICKLE1 | PRICKLE1 isoform 11. (831 aa) |
| | FZD1 | FZD1 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa) |
| | PTCH1 | PTCH1 isoform 8. (1428 aa) |
| | ENSPTRP00000087502 | annotation not available (347 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa) |
| | CLUAP1 | CLUAP1 isoform 5. (432 aa) |
| | AMBRA1 | AMBRA1 isoform 6. (1298 aa) |
| | ENSPTRP00000086171 | annotation not available (421 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (955 aa) |
| | SHROOM3 | SHROOM3 isoform 1. (1945 aa) |
| | MED12 | Mediator of RNA polymerase II transcription subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifi [...] (2182 aa) |
| | ENSPTRP00000085013 | annotation not available (166 aa) |
| | STIL | STIL centriolar assembly protein. (1288 aa) |
| | TMED2 | Transmembrane emp24 domain trafficking protein 2. (208 aa) |
| | TEAD2 | TEA domain transcription factor 2. (451 aa) |
| | CK820_G0054628 | PKD1 isoform 4. (3384 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa) |
| | RARG | Retinoic acid receptor, gamma. (456 aa) |
| | GRHL3 | Grainyhead like transcription factor 3. (626 aa) |
| | COBL | Cordon-bleu WH2 repeat protein. (1333 aa) |
| | ENSPTRP00000082302 | annotation not available (814 aa) |
| | ENSPTRP00000081955 | annotation not available (66 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | BMP4-2 | Bone morphogenetic protein 4. (408 aa) |
| | HES5-2 | Hes family bHLH transcription factor 5. (165 aa) |
| | ENSPTRP00000078649 | annotation not available (188 aa) |
| | CECR2 | CECR2 isoform 2. (1485 aa) |
| | CK820_G0021556 | TMED2 isoform 3. (200 aa) |
| | OPA1 | OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa) |
| | PLXNB2 | PLXNB2 isoform 1. (1838 aa) |
| | SALL4 | SALL4 isoform 1. (1053 aa) |
| | LOC737148 | Single-stranded DNA-binding protein 3 pseudogene. (331 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | ARHGAP35 | Glucocorticoid receptor DNA binding factor 1. (1519 aa) |
| | ENSPTRP00000074987 | annotation not available (189 aa) |
| | KDM6A | KDM6A isoform 1. (1453 aa) |
| | CK820_G0042370 | TEAD2 isoform 6. (427 aa) |
| | ENSPTRP00000074059 | annotation not available (180 aa) |
| | SUFU | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (519 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] (743 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | ENSPTRP00000071968 | annotation not available (115 aa) |
| | DEAF1 | Deformed epidermal autoregulatory factor 1 homolog; Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expressio [...] (537 aa) |
| | IFT172 | Intraflagellar transport 172 homolog. (1767 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (169 aa) |
| | ENSPTRP00000070303 | annotation not available (117 aa) |
| | ENSPTRP00000069579 | annotation not available (372 aa) |
| | LOC459002 | 40S ribosomal protein S7 pseudogene. (189 aa) |
| | RNF220 | Ring finger protein 220. (566 aa) |
| | DZIP1L | DAZ interacting zinc finger protein 1 like. (767 aa) |
| | TULP3 | TULP3 isoform 3; Belongs to the TUB family. (501 aa) |
| | SMO-2 | Smoothened, frizzled class receptor. (786 aa) |
| | TMEM107-2 | Transmembrane protein 107. (140 aa) |
| | ENSPTRP00000066737 | annotation not available (186 aa) |
| | LUZP1 | Leucine zipper protein 1. (1076 aa) |
| | PAX6 | PAX6 isoform 13. (436 aa) |
| | ENSPTRP00000065244 | annotation not available (463 aa) |
| | CK820_G0056924 | NPIPA2 isoform 1. (277 aa) |
| | PHACTR4 | Phosphatase and actin regulator. (712 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | ENSPTRP00000063809 | annotation not available (177 aa) |
| | C2CD3 | C2CD3 isoform 3. (2298 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | LOC735645 | 40S ribosomal protein S7 pseudogene. (177 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (487 aa) |
| | FOXA1 | FOXA1 isoform 1. (471 aa) |
| | CC2D2A | CC2D2A isoform 1. (1627 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (458 aa) |
| | ENSPTRP00000061866 | annotation not available (267 aa) |
| | SCRIB | SCRIB isoform 8. (959 aa) |
| | ITPK1 | Inositol 1,3,4-triphosphate 5/6 kinase. (414 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | CELSR1 | CELSR1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (2998 aa) |
| | HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2610 aa) |
| | BBS4 | Bardet-Biedl syndrome 4. (519 aa) |
| | TCTN1 | Tectonic family member 1. (592 aa) |
| | ENSPTRP00000055426 | annotation not available (200 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | RARA | RARA isoform 4. (624 aa) |
| | TRIM71 | Tripartite motif containing 71. (868 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | SOX4 | Transcription factor SOX. (474 aa) |
| | EN1 | Homeobox protein engrailed-like. (396 aa) |
| | ZNF358 | Zinc finger protein 358. (559 aa) |
| | TWIST1 | TWIST1 isoform 2. (163 aa) |
| | KIF20B | KIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa) |
| | WDPCP | WDPCP isoform 2. (746 aa) |
| | FZD6 | Frizzled homolog 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | TSC2 | Tuberous sclerosis 2. (1689 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (165 aa) |
| | GLI2 | GLI family zinc finger 2. (1587 aa) |
| | ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2. (350 aa) |
| | NOTCH1 | NOTCH1 isoform 1. (2555 aa) |
| | LHX2 | LHX2 isoform 1. (406 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | GRHL2 | Grainyhead like transcription factor 2. (625 aa) |
| | SOX17 | SOX17 isoform 1. (416 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | DLC1 | DLC1 Rho GTPase activating protein. (1528 aa) |
| | SMO | SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa) |
| | PLOD3 | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3. (738 aa) |
| | SEMA3C | SEMA3C isoform 1; Belongs to the semaphorin family. (751 aa) |
| | GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in re [...] (1580 aa) |
| | RALA | V-ral simian leukemia viral oncogene homolog A (Ras related). (206 aa) |
| | FERD3L | Fer3 like bHLH transcription factor. (166 aa) |
| | TBXT | T-box transcription factor T. (435 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like. (805 aa) |
| | MARCKS | Myristoylated alanine-rich protein kinase C substrate. (332 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (524 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (295 aa) |
| | INTU | Inturned planar cell polarity effector homolog. (911 aa) |
| | SEC24B | SEC24B isoform 1. (1286 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (968 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | WDR19 | WD repeat domain 19. (1342 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | IFT122 | IFT122 isoform 10. (1286 aa) |
| | IFT57 | Intraflagellar transport 57 homolog. (429 aa) |
| | ARL13B | ADP ribosylation factor like GTPase 13B. (428 aa) |
| | INKA1 | FAM212A isoform 1. (287 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2564 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | IFT52 | Intraflagellar transport 52 homolog. (437 aa) |
| | GBX2 | Gastrulation brain homeobox 2. (348 aa) |
| | LRP2 | LRP2 isoform 1. (4655 aa) |
| | SEMA4C | SEMA4C isoform 2; Belongs to the semaphorin family. (833 aa) |
| | RPS7 | 40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (418 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (413 aa) |
| | PRKACA | PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa) |
| | MKS1 | MKS transition zone complex subunit 1. (559 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | FZD2 | FZD2 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa) |
| | KAT2A | Histone acetyltransferase KAT2A isoform X1. (837 aa) |
| | NF1 | Neurofibromin 1. (2839 aa) |
| | TMEM107 | Transmembrane protein 107. (146 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (140 aa) |
| | RPGRIP1L | RPGRIP1L isoform 4. (1269 aa) |
| | IFT140 | Intraflagellar transport 140 homolog. (1471 aa) |
| | FOXB1 | FOXB1 isoform 3. (325 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa) |
| | SPINT1 | SPINT1 isoform 2. (529 aa) |
| | GSC | Homeobox protein goosecoid; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity); Belongs to the paired homeobox family. Bicoid subfamily. (257 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | MTHFD1 | MTHFD1 isoform 1. (1020 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (836 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | SALL2 | Spalt like transcription factor 2. (1007 aa) |
| | KDM2B | Lysine (K)-specific demethylase 2B. (1336 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | FOLR1 | Folate receptor alpha. (257 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | ADM | Adrenomedullin. (185 aa) |
| | NODAL | NODAL isoform 2. (347 aa) |
| | NUP133 | NUP133 isoform 1. (1156 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | PLXNA2 | PLXNA2 isoform 1. (1909 aa) |
| | VANGL2 | Vang-like protein. (521 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (573 aa) |
| | GLMN | Glomulin, FKBP associated protein. (594 aa) |
| | LMO4 | LIM domain only 4. (165 aa) |
| | BCL10 | B-cell CLL/lymphoma 10. (316 aa) |
| | SSBP3 | Single stranded DNA binding protein 3. (388 aa) |
| | EPHA2 | EPH receptor A2. (976 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (656 aa) |
| | SKI | V-ski sarcoma viral oncogene homolog (Avian). (736 aa) |
