STRINGSTRING
GHRH GHRH POU1F1 POU1F1 GHRHR GHRHR PITX2 PITX2 SLC6A3 SLC6A3 SOX2 SOX2 GATA2 GATA2 WNT4 WNT4 FGF8 FGF8 GHRHR-2 GHRHR-2 DRD2 DRD2 HES1 HES1 GSX1 GSX1 LHX3 LHX3 DUOX2 DUOX2 BMP2 BMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GHRHGrowth hormone releasing hormone. (108 aa)
POU1F1POU domain protein. (317 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
PITX2Homeobox protein. (324 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
SOX2SRY-box transcription factor 2. (319 aa)
GATA2GATA binding protein 2. (480 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GHRHR-2Growth hormone-releasing hormone receptor isoform X1. (447 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (490 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
GSX1GSX1 isoform 1. (264 aa)
LHX3LHX3 isoform 2. (402 aa)
DUOX2DUOX2 isoform 1. (1548 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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