STRINGSTRING
ABI1 ABI1 CTNNB1 CTNNB1 FLI1 FLI1 DMTN DMTN JAK3 JAK3 UBA5 UBA5 THOC5 THOC5 CSF3 CSF3 NBEAL2 NBEAL2 ZBTB46 ZBTB46 PABPC4 PABPC4 GAB3 GAB3 G6PD G6PD ATP6AP1 ATP6AP1 PIR PIR CCL19 CCL19 CK820_G0008402 CK820_G0008402 CCN4 CCN4 DCSTAMP DCSTAMP KAT6A KAT6A MFHAS1 MFHAS1 CLEC5A CLEC5A HIPK2 HIPK2 BPGM BPGM EPO EPO SLC25A40 SLC25A40 IKZF1 IKZF1 SNX10 SNX10 EIF2AK1 EIF2AK1 DLL1 DLL1 MYB MYB OSTM1 OSTM1 UFL1 UFL1 RHAG RHAG SRF SRF TREM2 TREM2 TSPO2 TSPO2 GLO1 GLO1 MAPK14 MAPK14 TRIM10 TRIM10 UBD UBD TMEM14C TMEM14C IRF4 IRF4 SFXN1 SFXN1 HSPA9 HSPA9 IL4 IL4 CSF2 CSF2 CAMK4 CAMK4 AP3B1 AP3B1 F2RL1 F2RL1 IL31RA IL31RA KIT KIT WDR1 WDR1 LYAR LYAR NRROS NRROS TF TF HCLS1 HCLS1 BAP1 BAP1 ALAS1 ALAS1 SNRK SNRK SLC25A38 SLC25A38 JAGN1 JAGN1 EP300 EP300 LIF LIF HSCB HSCB FAM210B FAM210B OCSTAMP OCSTAMP MMP9 MMP9 NCOA6 NCOA6 INHA INHA CASP8 CASP8 EPAS1 EPAS1 ID2 ID2 IL11 IL11 TGFB1 TGFB1 ZFP36 ZFP36 KLF2 KLF2 KLF1 KLF1 ZBTB7A ZBTB7A SBNO2 SBNO2 PRTN3 PRTN3 FASN FASN JMJD6 JMJD6 SLC4A1 SLC4A1 THRA THRA MED1 MED1 NF1 NF1 DHRS7B DHRS7B IL17C IL17C ZFPM1 ZFPM1 AHSP AHSP SOCS1 SOCS1 CIB1 CIB1 IREB2 IREB2 PML PML TMOD3 TMOD3 BATF BATF PSEN1 PSEN1 BMP4 BMP4 SRP54 SRP54 IL25 IL25 CEBPE CEBPE ACIN1 ACIN1 GPR183 GPR183 RB1 RB1 TNFSF11 TNFSF11 VPS33A VPS33A TESC TESC SH2B3 SH2B3 KITLG KITLG IFNG IFNG PDE1B PDE1B NCKAP1L NCKAP1L IAPP IAPP CLEC1B CLEC1B LTBR LTBR ZBTB16 ZBTB16 TCIRG1 TCIRG1 BATF2 BATF2 TRAF6 TRAF6 PRDX3 PRDX3 SIRT1 SIRT1 ABCB10 ABCB10 PARP1 PARP1 LBR LBR FLVCR1 FLVCR1 BATF3 BATF3 IL20 IL20 DYRK3 DYRK3 ATP5IF1 ATP5IF1 ENSPTRP00000000715 ENSPTRP00000000715 WASF2 WASF2 EPHA2 EPHA2 PIK3CD PIK3CD APP APP INHBA INHBA DNASE2 DNASE2 SIRT1-2 SIRT1-2 RUNX1 RUNX1 ENSPTRP00000092364 ENSPTRP00000092364 PLA2G10 PLA2G10 ENSPTRP00000091852 ENSPTRP00000091852 LRRK1 LRRK1 ENSPTRP00000091039 ENSPTRP00000091039 LOC739070 LOC739070 MEF2C MEF2C ENSPTRP00000090385 ENSPTRP00000090385 ACTN1 ACTN1 CASP9 CASP9 TNFRSF11A TNFRSF11A RPS19 RPS19 STAT5B STAT5B BRD1 BRD1 RELB RELB ENSPTRP00000088102 ENSPTRP00000088102 ENSPTRP00000087978 ENSPTRP00000087978 DHRS2 DHRS2 KCNQ1 KCNQ1 VPS33B VPS33B C15H15orf41 C15H15orf41 GATA1 GATA1 IRF8 IRF8 GPR68 GPR68 ADAR ADAR CEBPB CEBPB SP3 SP3 MITF MITF ITGB8-2 ITGB8-2 ENSPTRP00000084510 ENSPTRP00000084510 ANXA2 ANXA2 CK820_G0041942 CK820_G0041942 ENSPTRP00000084126 ENSPTRP00000084126 SPI1 SPI1 CLEC5A-2 CLEC5A-2 NCAPG2 NCAPG2 CDKN2B CDKN2B CEBPG CEBPG ITGB8 ITGB8 ZNF385A ZNF385A CDK5RAP3 CDK5RAP3 JAK2 JAK2 CITED2 CITED2 FARP2 FARP2 ENSPTRP00000081286 ENSPTRP00000081286 ENSPTRP00000081143 ENSPTRP00000081143 CSF1R CSF1R BMP4-2 BMP4-2 EPO-2 EPO-2 SMAD5 SMAD5 LEF1 LEF1 ENSPTRP00000079686 ENSPTRP00000079686 LOC459970 LOC459970 RBPJ RBPJ L3MBTL3 L3MBTL3 SH3PXD2A SH3PXD2A ERCC2 ERCC2 ENSPTRP00000079023 ENSPTRP00000079023 MYH9 MYH9 FOS FOS PAFAH1B1 PAFAH1B1 LOC741786 LOC741786 GAB3-2 GAB3-2 CDC42 CDC42 ENSPTRP00000077211 ENSPTRP00000077211 PIK3R1 PIK3R1 ALAS2 ALAS2 SRC SRC PPARG PPARG ADGRF5 ADGRF5 ENSPTRP00000076409 ENSPTRP00000076409 NOTCH2 NOTCH2 TSPAN2 TSPAN2 MAEA MAEA TGFBR2 TGFBR2 MAF MAF FOXP1 FOXP1 CD109 CD109 ENSPTRP00000074763 ENSPTRP00000074763 NKX2-3 NKX2-3 CD81 CD81 ENSPTRP00000074403 ENSPTRP00000074403 ITGB6 ITGB6 EIF2AK1-2 EIF2AK1-2 PTBP3 PTBP3 CALCR CALCR PTPN11-2 PTPN11-2 CREB1 CREB1 PTPN2 PTPN2 RASGRP4 RASGRP4 PIP4K2A PIP4K2A PKNOX1 PKNOX1 SLC11A2 SLC11A2 IL4-2 IL4-2 SLC25A40-2 SLC25A40-2 ENSPTRP00000071088 ENSPTRP00000071088 ENSPTRP00000070889 ENSPTRP00000070889 GP5 GP5 ARID4A ARID4A CSF1 CSF1 KMT2E KMT2E TNF TNF CBFA2T3 CBFA2T3 ETV2 ETV2 RPS14 RPS14 PABPC4L PABPC4L TET2 TET2 BCL6 BCL6 IL15 IL15 OSCAR OSCAR ENSPTRP00000067174 ENSPTRP00000067174 ENSPTRP00000066810 ENSPTRP00000066810 ENSPTRP00000066621 ENSPTRP00000066621 MEIS1 MEIS1 TGFBR3 TGFBR3 CK820_G0008402-2 CK820_G0008402-2 ENSPTRP00000066267 ENSPTRP00000066267 ENSPTRP00000066121 ENSPTRP00000066121 IFI16 IFI16 ENSPTRP00000065244 ENSPTRP00000065244 GATA3 GATA3 TIRAP TIRAP TAL1 TAL1 FLNA FLNA ENSPTRP00000062821 ENSPTRP00000062821 THPO THPO RHEX RHEX MPIG6B MPIG6B PTPN11 PTPN11 KAT8 KAT8 EVI2B EVI2B RPS6 RPS6 SLC25A5 SLC25A5 CBFB CBFB GP9 GP9 GP1BB GP1BB CD4 CD4 CASP3 CASP3 GATA2 GATA2 SFRP1 SFRP1 GP1BA GP1BA CCR7 CCR7 RCOR1 RCOR1 PTPN6 PTPN6 EFNA2 EFNA2 JUNB JUNB PDE2A PDE2A GIMAP1 GIMAP1 NKAP NKAP TFRC TFRC LYN LYN GAB2 GAB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABI1Abl interactor 1. (508 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
DMTNDematin actin binding protein. (405 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
UBA5Ubiquitin-like modifier-activating enzyme 5. (404 aa)
THOC5THOC5 isoform 1. (683 aa)
CSF3Colony stimulating factor 3 (Granulocyte). (204 aa)
NBEAL2NBEAL2 isoform 1. (2751 aa)
ZBTB46Zinc finger and BTB domain containing 46. (589 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
GAB3GRB2 associated binding protein 3. (587 aa)
G6PDGlucose-6-phosphate dehydrogenase. (560 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (470 aa)
PIRPirin (Iron-binding nuclear protein); Belongs to the pirin family. (290 aa)
CCL19C-C motif chemokine. (98 aa)
CK820_G0008402Annexin. (233 aa)
CCN4WISP1 isoform 1. (367 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
CLEC5AC-type lectin domain containing 5A. (188 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
SLC25A40Solute carrier family 25, member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
SNX10Sorting nexin 10. (201 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1. (630 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
OSTM1Osteoclastogenesis associated transmembrane protein 1. (334 aa)
UFL1UFM1 specific ligase 1. (794 aa)
RHAGRHAG isoform 2; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (441 aa)
SRFSerum response factor (C-fos serum response element-binding transcription factor). (508 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TSPO2Translocator protein 2. (170 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa)
MAPK14Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
TRIM10Tripartite motif-containing protein 10; Seems to play an important role in erythropoiesis. (395 aa)
UBDUBD isoform 1. (165 aa)
TMEM14CTransmembrane protein 14C. (112 aa)
IRF4Interferon regulatory factor 4. (451 aa)
SFXN1Sidoreflexin. (322 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa)
CSF2Colony stimulating factor 2. (144 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1045 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
IL31RAInterleukin 31 receptor A. (764 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
WDR1WD repeat domain 1. (606 aa)
LYARLYAR isoform 2. (405 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
TFSerotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity). (698 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
ALAS15-aminolevulinate synthase. (640 aa)
SNRKSNF related kinase. (765 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
JAGN1Jagunal homolog 1. (183 aa)
EP300E1A binding protein p300. (2175 aa)
LIFLeukemia inhibitory factor (Cholinergic differentiation factor). (202 aa)
HSCBHscB mitochondrial iron-sulfur cluster cochaperone. (235 aa)
FAM210BFAM210B isoform 1. (192 aa)
OCSTAMPOCSTAMP isoform 1. (565 aa)
MMP9Matrix metallopeptidase 9. (699 aa)
NCOA6Nuclear receptor coactivator 6. (2066 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
CASP8Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (538 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
IL11IL11 isoform 1. (199 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ZFP36Zinc finger protein 36, C3H type, homolog. (332 aa)
KLF2Kruppel-like factor 2 (Lung). (355 aa)
KLF1Kruppel like factor 1. (362 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
SBNO2SBNO2 isoform 2. (1350 aa)
PRTN3PRTN3 isoform 2. (256 aa)
FASNFatty acid synthase. (2511 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
SLC4A1Anion exchange protein. (921 aa)
THRAThyroid hormone receptor, alpha (Erythroblastic leukemia viral (V-erb-a) oncogene homolog, avian). (617 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
NF1Neurofibromin 1. (2839 aa)
DHRS7BDHRS7B isoform 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
IL17CIL17C isoform 2. (197 aa)
ZFPM1ZFPM1 isoform 1. (974 aa)
AHSPAlpha hemoglobin stabilizing protein. (102 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
CIB1Calcium and integrin binding 1. (231 aa)
IREB2Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa)
PMLPML isoform 6. (836 aa)
TMOD3Tropomodulin 3 (Ubiquitous). (352 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
IL25IL25 isoform 2. (177 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
ACIN1ACIN1 isoform 7. (1342 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
RB1RB transcriptional corepressor 1. (928 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
VPS33AVacuolar protein sorting 33 homolog A; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
TESCTESC isoform 2. (214 aa)
SH2B3SH2B adaptor protein 3. (575 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
PDE1BPhosphodiesterase. (536 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
IAPPIslet amyloid polypeptide. (89 aa)
CLEC1BCLEC1B isoform 3. (228 aa)
LTBRLymphotoxin beta receptor (TNFR superfamily, member 3). (435 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (274 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PRDX3PRDX3 isoform 1. (256 aa)
SIRT1SIRT1 isoform 2. (751 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
LBRLamin B receptor. (615 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (569 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (123 aa)
IL20IL20 isoform 1. (176 aa)
DYRK3Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3. (588 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (106 aa)
ENSPTRP00000000715Wiskott-Aldrich syndrome protein family member 2-like. (492 aa)
WASF2WAS protein family, member 2. (498 aa)
EPHA2EPH receptor A2. (976 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa)
INHBAInhibin subunit beta A. (426 aa)
DNASE2Deoxyribonuclease II, lysosomal. (360 aa)
SIRT1-2Sirtuin 1. (751 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
ENSPTRP00000092364annotation not available (574 aa)
PLA2G10Group 10 secretory phospholipase A2-like. (165 aa)
ENSPTRP00000091852annotation not available (179 aa)
LRRK1Leucine-rich repeat kinase 1. (2015 aa)
ENSPTRP00000091039annotation not available (117 aa)
LOC739070PLA2G10 isoform 1. (165 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ENSPTRP00000090385annotation not available (699 aa)
ACTN1Actinin, alpha 1. (870 aa)
CASP9CASP9 isoform 4; Belongs to the peptidase C14A family. (421 aa)
TNFRSF11ATNF receptor superfamily member 11a. (617 aa)
RPS19Ribosomal protein S19. (145 aa)
STAT5BSignal transducer and activator of transcription. (772 aa)
BRD1Bromodomain containing 1. (1189 aa)
RELBRELB isoform 3. (567 aa)
ENSPTRP00000088102annotation not available (203 aa)
ENSPTRP00000087978annotation not available (470 aa)
DHRS2DHRS2 isoform 3. (280 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
VPS33BVPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (617 aa)
C15H15orf41Chromosome 15 C15orf41 homolog. (287 aa)
GATA1GATA binding protein 1. (413 aa)
IRF8Interferon regulatory factor 8. (426 aa)
GPR68GPR68 isoform 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ADARAdenosine deaminase, RNA-specific. (1229 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
SP3Sp3 transcription factor. (781 aa)
MITFMITF isoform 1. (519 aa)
ITGB8-2Integrin subunit beta 8. (780 aa)
ENSPTRP00000084510annotation not available (456 aa)
ANXA2Annexin. (357 aa)
CK820_G0041942OSCAR isoform 2. (252 aa)
ENSPTRP00000084126annotation not available (117 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
CLEC5A-2C-type lectin domain containing 5A. (188 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1156 aa)
CDKN2BCyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). (138 aa)
CEBPGCCAAT/enhancer binding protein (C/EBP), gamma. (150 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (780 aa)
ZNF385AZinc finger protein 385A. (414 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (534 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1054 aa)
ENSPTRP00000081286annotation not available (61 aa)
ENSPTRP00000081143annotation not available (219 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
BMP4-2Bone morphogenetic protein 4. (408 aa)
EPO-2Erythropoietin. (193 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
ENSPTRP00000079686annotation not available (213 aa)
LOC459970Stress-70 protein, mitochondrial pseudogene. (640 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
SH3PXD2ASH3 and PX domains 2A. (1133 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ENSPTRP00000079023annotation not available (237 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa)
LOC741786CDK5RAP3 isoform 6. (501 aa)
GAB3-2GRB2-associated-binding protein 3 isoform X1. (611 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
ENSPTRP00000077211annotation not available (269 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
ALAS25-aminolevulinate synthase. (587 aa)
SRCTyrosine-protein kinase. (542 aa)
PPARGPeroxisome proliferator-activated receptor gamma isoform X2. (505 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
ENSPTRP00000076409annotation not available (281 aa)
NOTCH2NOTCH2 isoform 1. (2612 aa)
TSPAN2Tetraspanin. (228 aa)
MAEAMacrophage erythroblast attacher. (378 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa)
MAFMAF isoform 2; Belongs to the bZIP family. (402 aa)
FOXP1FOXP1 isoform 2. (693 aa)
CD109CD109 isoform 3. (1446 aa)
ENSPTRP00000074763annotation not available (520 aa)
NKX2-3NKX2-3 isoform 1. (366 aa)
CD81CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] (303 aa)
ENSPTRP00000074403annotation not available (115 aa)
ITGB6ITGB6 isoform 3. (701 aa)
EIF2AK1-2Eukaryotic translation initiation factor 2 alpha kinase 1. (647 aa)
PTBP3Polypyrimidine tract binding protein 3. (558 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
PTPN11-2Protein tyrosine phosphatase non-receptor type 11. (579 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (421 aa)
RASGRP4RAS guanyl releasing protein 4. (699 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase, type II, alpha. (406 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
SLC11A2SLC11A2 isoform 1. (590 aa)
IL4-2Interleukin 4. (153 aa)
SLC25A40-2Solute carrier family 25 member 40. (338 aa)
ENSPTRP00000071088annotation not available (500 aa)
ENSPTRP00000070889annotation not available (121 aa)
GP5GP5 isoform 1. (560 aa)
ARID4AAT-rich interaction domain 4A. (1259 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa)
KMT2EMyeloid/lymphoid or mixed-lineage leukemia 5. (1877 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
CBFA2T3CBFA2/RUNX1 translocation partner 3. (653 aa)
ETV2ETV2 isoform 5. (370 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
PABPC4LPABPC4L isoform 1. (430 aa)
TET2TET2 isoform 1. (2023 aa)
BCL6BCL6 transcription repressor. (706 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
OSCAROSCAR isoform 3. (305 aa)
ENSPTRP00000067174annotation not available (502 aa)
ENSPTRP00000066810annotation not available (262 aa)
ENSPTRP00000066621annotation not available (709 aa)
MEIS1MEIS1 isoform 7. (465 aa)
TGFBR3Transforming growth factor, beta receptor III. (861 aa)
CK820_G0008402-2Annexin. (325 aa)
ENSPTRP00000066267annotation not available (151 aa)
ENSPTRP00000066121annotation not available (305 aa)
IFI16IFI16 isoform 4. (733 aa)
ENSPTRP00000065244annotation not available (463 aa)
GATA3GATA binding protein 3. (444 aa)
TIRAPToll-interleukin 1 receptor (TIR) domain containing adaptor protein. (235 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
FLNAFLNA isoform 8. (2711 aa)
ENSPTRP00000062821annotation not available (220 aa)
THPOTHPO isoform 1. (353 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (172 aa)
MPIG6BMPIG6B isoform 11. (242 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
EVI2BEcotropic viral integration site 2B. (448 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
SLC25A5Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
CBFBCore-binding factor, beta subunit. (182 aa)
GP9Glycoprotein IX platelet. (177 aa)
GP1BBGlycoprotein Ib (Platelet), beta polypeptide. (206 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa)
GATA2GATA binding protein 2. (480 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
GP1BAGP1BA isoform 1. (653 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
RCOR1REST corepressor 1. (482 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
EFNA2EFNA2 isoform 1; Belongs to the ephrin family. (190 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
PDE2APhosphodiesterase. (941 aa)
GIMAP1GTPase IMAP family member 5. (500 aa)
NKAPNFKB activating protein. (415 aa)
TFRCTransferrin receptor (P90, CD71). (760 aa)
LYNTyrosine-protein kinase. (512 aa)
GAB2GRB2-associated-binding protein 2. (676 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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