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ABI1 | Abl interactor 1. (508 aa) | ||||
CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) | ||||
FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (452 aa) | ||||
DMTN | Dematin actin binding protein. (405 aa) | ||||
JAK3 | Tyrosine-protein kinase. (1124 aa) | ||||
UBA5 | Ubiquitin-like modifier-activating enzyme 5. (404 aa) | ||||
THOC5 | THOC5 isoform 1. (683 aa) | ||||
CSF3 | Colony stimulating factor 3 (Granulocyte). (204 aa) | ||||
NBEAL2 | NBEAL2 isoform 1. (2751 aa) | ||||
ZBTB46 | Zinc finger and BTB domain containing 46. (589 aa) | ||||
PABPC4 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa) | ||||
GAB3 | GRB2 associated binding protein 3. (587 aa) | ||||
G6PD | Glucose-6-phosphate dehydrogenase. (560 aa) | ||||
ATP6AP1 | ATPase H+ transporting accessory protein 1. (470 aa) | ||||
PIR | Pirin (Iron-binding nuclear protein); Belongs to the pirin family. (290 aa) | ||||
CCL19 | C-C motif chemokine. (98 aa) | ||||
CK820_G0008402 | Annexin. (233 aa) | ||||
CCN4 | WISP1 isoform 1. (367 aa) | ||||
DCSTAMP | Dendrocyte expressed seven transmembrane protein. (470 aa) | ||||
KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa) | ||||
MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1. (1052 aa) | ||||
CLEC5A | C-type lectin domain containing 5A. (188 aa) | ||||
HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) | ||||
BPGM | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa) | ||||
EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa) | ||||
SLC25A40 | Solute carrier family 25, member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa) | ||||
IKZF1 | IKAROS family zinc finger 1. (519 aa) | ||||
SNX10 | Sorting nexin 10. (201 aa) | ||||
EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1. (630 aa) | ||||
DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) | ||||
MYB | MYB proto-oncogene, transcription factor. (761 aa) | ||||
OSTM1 | Osteoclastogenesis associated transmembrane protein 1. (334 aa) | ||||
UFL1 | UFM1 specific ligase 1. (794 aa) | ||||
RHAG | RHAG isoform 2; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (441 aa) | ||||
SRF | Serum response factor (C-fos serum response element-binding transcription factor). (508 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) | ||||
TSPO2 | Translocator protein 2. (170 aa) | ||||
GLO1 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa) | ||||
MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) | ||||
TRIM10 | Tripartite motif-containing protein 10; Seems to play an important role in erythropoiesis. (395 aa) | ||||
UBD | UBD isoform 1. (165 aa) | ||||
TMEM14C | Transmembrane protein 14C. (112 aa) | ||||
IRF4 | Interferon regulatory factor 4. (451 aa) | ||||
SFXN1 | Sidoreflexin. (322 aa) | ||||
HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. (153 aa) | ||||
CSF2 | Colony stimulating factor 2. (144 aa) | ||||
CAMK4 | Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1045 aa) | ||||
F2RL1 | F2R like trypsin receptor 1. (397 aa) | ||||
IL31RA | Interleukin 31 receptor A. (764 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
WDR1 | WD repeat domain 1. (606 aa) | ||||
LYAR | LYAR isoform 2. (405 aa) | ||||
NRROS | Negative regulator of reactive oxygen species. (692 aa) | ||||
TF | Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity). (698 aa) | ||||
HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (484 aa) | ||||
BAP1 | Ubiquitin carboxyl-terminal hydrolase. (729 aa) | ||||
ALAS1 | 5-aminolevulinate synthase. (640 aa) | ||||
SNRK | SNF related kinase. (765 aa) | ||||
SLC25A38 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa) | ||||
JAGN1 | Jagunal homolog 1. (183 aa) | ||||
EP300 | E1A binding protein p300. (2175 aa) | ||||
LIF | Leukemia inhibitory factor (Cholinergic differentiation factor). (202 aa) | ||||
HSCB | HscB mitochondrial iron-sulfur cluster cochaperone. (235 aa) | ||||
FAM210B | FAM210B isoform 1. (192 aa) | ||||
OCSTAMP | OCSTAMP isoform 1. (565 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (699 aa) | ||||
NCOA6 | Nuclear receptor coactivator 6. (2066 aa) | ||||
INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) | ||||
CASP8 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (538 aa) | ||||
EPAS1 | Endothelial PAS domain protein 1. (870 aa) | ||||
ID2 | Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa) | ||||
IL11 | IL11 isoform 1. (199 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
ZFP36 | Zinc finger protein 36, C3H type, homolog. (332 aa) | ||||
KLF2 | Kruppel-like factor 2 (Lung). (355 aa) | ||||
KLF1 | Kruppel like factor 1. (362 aa) | ||||
ZBTB7A | Zinc finger and BTB domain containing 7A. (584 aa) | ||||
SBNO2 | SBNO2 isoform 2. (1350 aa) | ||||
PRTN3 | PRTN3 isoform 2. (256 aa) | ||||
FASN | Fatty acid synthase. (2511 aa) | ||||
JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa) | ||||
SLC4A1 | Anion exchange protein. (921 aa) | ||||
THRA | Thyroid hormone receptor, alpha (Erythroblastic leukemia viral (V-erb-a) oncogene homolog, avian). (617 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa) | ||||
NF1 | Neurofibromin 1. (2839 aa) | ||||
DHRS7B | DHRS7B isoform 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa) | ||||
IL17C | IL17C isoform 2. (197 aa) | ||||
ZFPM1 | ZFPM1 isoform 1. (974 aa) | ||||
AHSP | Alpha hemoglobin stabilizing protein. (102 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (211 aa) | ||||
CIB1 | Calcium and integrin binding 1. (231 aa) | ||||
IREB2 | Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa) | ||||
PML | PML isoform 6. (836 aa) | ||||
TMOD3 | Tropomodulin 3 (Ubiquitous). (352 aa) | ||||
BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (408 aa) | ||||
SRP54 | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa) | ||||
IL25 | IL25 isoform 2. (177 aa) | ||||
CEBPE | CCAAT/enhancer-binding protein. (281 aa) | ||||
ACIN1 | ACIN1 isoform 7. (1342 aa) | ||||
GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa) | ||||
RB1 | RB transcriptional corepressor 1. (928 aa) | ||||
TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) | ||||
VPS33A | Vacuolar protein sorting 33 homolog A; Belongs to the STXBP/unc-18/SEC1 family. (596 aa) | ||||
TESC | TESC isoform 2. (214 aa) | ||||
SH2B3 | SH2B adaptor protein 3. (575 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) | ||||
PDE1B | Phosphodiesterase. (536 aa) | ||||
NCKAP1L | NCK associated protein 1 like. (1127 aa) | ||||
IAPP | Islet amyloid polypeptide. (89 aa) | ||||
CLEC1B | CLEC1B isoform 3. (228 aa) | ||||
LTBR | Lymphotoxin beta receptor (TNFR superfamily, member 3). (435 aa) | ||||
ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) | ||||
TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) | ||||
BATF2 | Basic leucine zipper ATF-like transcription factor 2. (274 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
PRDX3 | PRDX3 isoform 1. (256 aa) | ||||
SIRT1 | SIRT1 isoform 2. (751 aa) | ||||
ABCB10 | ATP binding cassette subfamily B member 10. (738 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) | ||||
LBR | Lamin B receptor. (615 aa) | ||||
FLVCR1 | Feline leukemia virus subgroup C cellular receptor 1. (569 aa) | ||||
BATF3 | Basic leucine zipper ATF-like transcription factor 3. (123 aa) | ||||
IL20 | IL20 isoform 1. (176 aa) | ||||
DYRK3 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3. (588 aa) | ||||
ATP5IF1 | ATP synthase inhibitory factor subunit 1. (106 aa) | ||||
ENSPTRP00000000715 | Wiskott-Aldrich syndrome protein family member 2-like. (492 aa) | ||||
WASF2 | WAS protein family, member 2. (498 aa) | ||||
EPHA2 | EPH receptor A2. (976 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa) | ||||
INHBA | Inhibin subunit beta A. (426 aa) | ||||
DNASE2 | Deoxyribonuclease II, lysosomal. (360 aa) | ||||
SIRT1-2 | Sirtuin 1. (751 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
ENSPTRP00000092364 | annotation not available (574 aa) | ||||
PLA2G10 | Group 10 secretory phospholipase A2-like. (165 aa) | ||||
ENSPTRP00000091852 | annotation not available (179 aa) | ||||
LRRK1 | Leucine-rich repeat kinase 1. (2015 aa) | ||||
ENSPTRP00000091039 | annotation not available (117 aa) | ||||
LOC739070 | PLA2G10 isoform 1. (165 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
ENSPTRP00000090385 | annotation not available (699 aa) | ||||
ACTN1 | Actinin, alpha 1. (870 aa) | ||||
CASP9 | CASP9 isoform 4; Belongs to the peptidase C14A family. (421 aa) | ||||
TNFRSF11A | TNF receptor superfamily member 11a. (617 aa) | ||||
RPS19 | Ribosomal protein S19. (145 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (772 aa) | ||||
BRD1 | Bromodomain containing 1. (1189 aa) | ||||
RELB | RELB isoform 3. (567 aa) | ||||
ENSPTRP00000088102 | annotation not available (203 aa) | ||||
ENSPTRP00000087978 | annotation not available (470 aa) | ||||
DHRS2 | DHRS2 isoform 3. (280 aa) | ||||
KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa) | ||||
VPS33B | VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (617 aa) | ||||
C15H15orf41 | Chromosome 15 C15orf41 homolog. (287 aa) | ||||
GATA1 | GATA binding protein 1. (413 aa) | ||||
IRF8 | Interferon regulatory factor 8. (426 aa) | ||||
GPR68 | GPR68 isoform 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) | ||||
ADAR | Adenosine deaminase, RNA-specific. (1229 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein. (347 aa) | ||||
SP3 | Sp3 transcription factor. (781 aa) | ||||
MITF | MITF isoform 1. (519 aa) | ||||
ITGB8-2 | Integrin subunit beta 8. (780 aa) | ||||
ENSPTRP00000084510 | annotation not available (456 aa) | ||||
ANXA2 | Annexin. (357 aa) | ||||
CK820_G0041942 | OSCAR isoform 2. (252 aa) | ||||
ENSPTRP00000084126 | annotation not available (117 aa) | ||||
SPI1 | Spi-1 proto-oncogene. (270 aa) | ||||
CLEC5A-2 | C-type lectin domain containing 5A. (188 aa) | ||||
NCAPG2 | Non-SMC condensin II complex subunit G2. (1156 aa) | ||||
CDKN2B | Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). (138 aa) | ||||
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma. (150 aa) | ||||
ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (780 aa) | ||||
ZNF385A | Zinc finger protein 385A. (414 aa) | ||||
CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (534 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1143 aa) | ||||
CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) | ||||
FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1054 aa) | ||||
ENSPTRP00000081286 | annotation not available (61 aa) | ||||
ENSPTRP00000081143 | annotation not available (219 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
BMP4-2 | Bone morphogenetic protein 4. (408 aa) | ||||
EPO-2 | Erythropoietin. (193 aa) | ||||
SMAD5 | Mothers against decapentaplegic homolog. (465 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (414 aa) | ||||
ENSPTRP00000079686 | annotation not available (213 aa) | ||||
LOC459970 | Stress-70 protein, mitochondrial pseudogene. (640 aa) | ||||
RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (500 aa) | ||||
L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) | ||||
SH3PXD2A | SH3 and PX domains 2A. (1133 aa) | ||||
ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) | ||||
ENSPTRP00000079023 | annotation not available (237 aa) | ||||
MYH9 | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (413 aa) | ||||
LOC741786 | CDK5RAP3 isoform 6. (501 aa) | ||||
GAB3-2 | GRB2-associated-binding protein 3 isoform X1. (611 aa) | ||||
CDC42 | Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa) | ||||
ENSPTRP00000077211 | annotation not available (269 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa) | ||||
ALAS2 | 5-aminolevulinate synthase. (587 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma isoform X2. (505 aa) | ||||
ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa) | ||||
ENSPTRP00000076409 | annotation not available (281 aa) | ||||
NOTCH2 | NOTCH2 isoform 1. (2612 aa) | ||||
TSPAN2 | Tetraspanin. (228 aa) | ||||
MAEA | Macrophage erythroblast attacher. (378 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa) | ||||
MAF | MAF isoform 2; Belongs to the bZIP family. (402 aa) | ||||
FOXP1 | FOXP1 isoform 2. (693 aa) | ||||
CD109 | CD109 isoform 3. (1446 aa) | ||||
ENSPTRP00000074763 | annotation not available (520 aa) | ||||
NKX2-3 | NKX2-3 isoform 1. (366 aa) | ||||
CD81 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] (303 aa) | ||||
ENSPTRP00000074403 | annotation not available (115 aa) | ||||
ITGB6 | ITGB6 isoform 3. (701 aa) | ||||
EIF2AK1-2 | Eukaryotic translation initiation factor 2 alpha kinase 1. (647 aa) | ||||
PTBP3 | Polypyrimidine tract binding protein 3. (558 aa) | ||||
CALCR | Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa) | ||||
PTPN11-2 | Protein tyrosine phosphatase non-receptor type 11. (579 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
PTPN2 | Tyrosine-protein phosphatase non-receptor type. (421 aa) | ||||
RASGRP4 | RAS guanyl releasing protein 4. (699 aa) | ||||
PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha. (406 aa) | ||||
PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) | ||||
SLC11A2 | SLC11A2 isoform 1. (590 aa) | ||||
IL4-2 | Interleukin 4. (153 aa) | ||||
SLC25A40-2 | Solute carrier family 25 member 40. (338 aa) | ||||
ENSPTRP00000071088 | annotation not available (500 aa) | ||||
ENSPTRP00000070889 | annotation not available (121 aa) | ||||
GP5 | GP5 isoform 1. (560 aa) | ||||
ARID4A | AT-rich interaction domain 4A. (1259 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa) | ||||
KMT2E | Myeloid/lymphoid or mixed-lineage leukemia 5. (1877 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) | ||||
CBFA2T3 | CBFA2/RUNX1 translocation partner 3. (653 aa) | ||||
ETV2 | ETV2 isoform 5. (370 aa) | ||||
RPS14 | Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa) | ||||
PABPC4L | PABPC4L isoform 1. (430 aa) | ||||
TET2 | TET2 isoform 1. (2023 aa) | ||||
BCL6 | BCL6 transcription repressor. (706 aa) | ||||
IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
OSCAR | OSCAR isoform 3. (305 aa) | ||||
ENSPTRP00000067174 | annotation not available (502 aa) | ||||
ENSPTRP00000066810 | annotation not available (262 aa) | ||||
ENSPTRP00000066621 | annotation not available (709 aa) | ||||
MEIS1 | MEIS1 isoform 7. (465 aa) | ||||
TGFBR3 | Transforming growth factor, beta receptor III. (861 aa) | ||||
CK820_G0008402-2 | Annexin. (325 aa) | ||||
ENSPTRP00000066267 | annotation not available (151 aa) | ||||
ENSPTRP00000066121 | annotation not available (305 aa) | ||||
IFI16 | IFI16 isoform 4. (733 aa) | ||||
ENSPTRP00000065244 | annotation not available (463 aa) | ||||
GATA3 | GATA binding protein 3. (444 aa) | ||||
TIRAP | Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (235 aa) | ||||
TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa) | ||||
FLNA | FLNA isoform 8. (2711 aa) | ||||
ENSPTRP00000062821 | annotation not available (220 aa) | ||||
THPO | THPO isoform 1. (353 aa) | ||||
RHEX | Regulator of hemoglobinization and erythroid cell expansion. (172 aa) | ||||
MPIG6B | MPIG6B isoform 11. (242 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) | ||||
KAT8 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa) | ||||
EVI2B | Ecotropic viral integration site 2B. (448 aa) | ||||
RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) | ||||
SLC25A5 | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
CBFB | Core-binding factor, beta subunit. (182 aa) | ||||
GP9 | Glycoprotein IX platelet. (177 aa) | ||||
GP1BB | Glycoprotein Ib (Platelet), beta polypeptide. (206 aa) | ||||
CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) | ||||
CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa) | ||||
GATA2 | GATA binding protein 2. (480 aa) | ||||
SFRP1 | Secreted frizzled-related protein 1. (314 aa) | ||||
GP1BA | GP1BA isoform 1. (653 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) | ||||
RCOR1 | REST corepressor 1. (482 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
EFNA2 | EFNA2 isoform 1; Belongs to the ephrin family. (190 aa) | ||||
JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) | ||||
PDE2A | Phosphodiesterase. (941 aa) | ||||
GIMAP1 | GTPase IMAP family member 5. (500 aa) | ||||
NKAP | NFKB activating protein. (415 aa) | ||||
TFRC | Transferrin receptor (P90, CD71). (760 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
GAB2 | GRB2-associated-binding protein 2. (676 aa) |