42 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C20H20orf27	C20orf27 isoform 2. (174 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (307 aa)
	GIPC3	GIPC PDZ domain containing family member 3. (312 aa)
	LRG1	Leucine-rich alpha-2-glycoprotein. (347 aa)
	GIPC1	GIPC1 isoform 3. (333 aa)
	SLC2A10	Solute carrier family 2 (Facilitated glucose transporter), member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)
	EP300	E1A binding protein p300. (2175 aa)
	ING2	Inhibitor of growth protein. (280 aa)
	HSP90AB1	HSP90AB1 isoform 1. (688 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1198 aa)
	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
	AXIN1	AXIN1 isoform 2. (859 aa)
	ADAM17	ADAM17 isoform 3. (999 aa)
	SDCBP	Syndecan binding protein. (324 aa)
	SNW1	SNW domain containing 1. (571 aa)
	ENSPTRP00000065909	annotation not available (145 aa)
	TGFBR3	Transforming growth factor, beta receptor III. (861 aa)
	THBS1	Thrombospondin 1. (1173 aa)
	GIPC2	GIPC2 isoform 1. (315 aa)
	DAB2	Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa)
	LOC739666	Syntenin-1-like. (289 aa)
	CREBBP	CREB binding protein. (2442 aa)
	FLCN	T0180863 isoform 1. (579 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	ENSPTRP00000081714	annotation not available (310 aa)
	CDKN2B	Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4). (138 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
	NPNT	NPNT isoform 10. (611 aa)
	ENSPTRP00000086563	annotation not available (245 aa)
	FERMT1	Fermitin family member 1. (677 aa)
	LOC107968084	Heat shock protein HSP 90-beta-like. (361 aa)
	ENSPTRP00000089475	annotation not available (268 aa)
	ENSPTRP00000089693	annotation not available (226 aa)
	CDKN1C	CDKN1C isoform 1. (288 aa)
	ENSPTRP00000090863	annotation not available (256 aa)
	ZEB2	Zinc finger E-box binding homeobox 2. (1253 aa)
	LOC461365	Heat shock protein HSP 90-beta pseudogene. (584 aa)
	MEN1	MEN1 isoform 14. (615 aa)
	RNF111	RNF111 isoform 5. (1003 aa)
	MYOCD	MYOCD isoform 2. (986 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	DAB2	ENSPTRP00000042391	ENSPTRP00000071697	AXIN1 isoform 2.	Disabled homolog 2, mitogen-responsive phosphoprotein.	0.720
AXIN1	HIPK2	ENSPTRP00000042391	ENSPTRP00000033846	AXIN1 isoform 2.	Homeodomain interacting protein kinase 2.	0.863
AXIN1	RNF111	ENSPTRP00000042391	ENSPTRP00000012176	AXIN1 isoform 2.	RNF111 isoform 5.	0.751
AXIN1	SMAD4	ENSPTRP00000042391	ENSPTRP00000017047	AXIN1 isoform 2.	Mothers against decapentaplegic homolog.	0.422
AXIN1	STK11	ENSPTRP00000042391	ENSPTRP00000017320	AXIN1 isoform 2.	Serine/threonine kinase 11; Belongs to the protein kinase superfamily.	0.852
CDKN1C	CDKN2B	ENSPTRP00000090407	ENSPTRP00000082876	CDKN1C isoform 1.	Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4).	0.699
CDKN1C	SMAD4	ENSPTRP00000090407	ENSPTRP00000017047	CDKN1C isoform 1.	Mothers against decapentaplegic homolog.	0.490
CDKN2B	CDKN1C	ENSPTRP00000082876	ENSPTRP00000090407	Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4).	CDKN1C isoform 1.	0.699
CDKN2B	SMAD4	ENSPTRP00000082876	ENSPTRP00000017047	Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4).	Mothers against decapentaplegic homolog.	0.555
CITED1	CREBBP	ENSPTRP00000037868	ENSPTRP00000074980	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	CREB binding protein.	0.701
CITED1	EP300	ENSPTRP00000037868	ENSPTRP00000024841	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	E1A binding protein p300.	0.962
CITED1	SMAD4	ENSPTRP00000037868	ENSPTRP00000017047	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Mothers against decapentaplegic homolog.	0.564
CITED2	CREBBP	ENSPTRP00000081552	ENSPTRP00000074980	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	CREB binding protein.	0.971
CITED2	EP300	ENSPTRP00000081552	ENSPTRP00000024841	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	E1A binding protein p300.	0.995
CREBBP	CITED1	ENSPTRP00000074980	ENSPTRP00000037868	CREB binding protein.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	0.701
CREBBP	CITED2	ENSPTRP00000074980	ENSPTRP00000081552	CREB binding protein.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	0.971
CREBBP	ENSPTRP00000081714	ENSPTRP00000074980	ENSPTRP00000081714	CREB binding protein.	annotation not available	0.654
CREBBP	ENSPTRP00000089693	ENSPTRP00000074980	ENSPTRP00000089693	CREB binding protein.	annotation not available	0.498
CREBBP	EP300	ENSPTRP00000074980	ENSPTRP00000024841	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	HIPK2	ENSPTRP00000074980	ENSPTRP00000033846	CREB binding protein.	Homeodomain interacting protein kinase 2.	0.744