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| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3. (254 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | FCHSD2 | FCH and double SH3 domains 2. (764 aa) |
| | ENSPTRP00000092498 | Supervillin-like. (133 aa) |
| | SCIN-2 | SCIN isoform 2. (715 aa) |
| | SHROOM2 | Shroom family member 2. (1616 aa) |
| | CARMIL2 | CARMIL2 isoform 2. (1436 aa) |
| | WAS-2 | WASP actin nucleation promoting factor. (502 aa) |
| | MYADM | Myeloid-associated differentiation marker. (322 aa) |
| | TMOD2 | Tropomodulin 2 (Neuronal). (351 aa) |
| | ENSPTRP00000091405 | annotation not available (334 aa) |
| | VASP | Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa) |
| | ENSPTRP00000090995 | annotation not available (206 aa) |
| | SSH1 | Slingshot homolog 1. (1062 aa) |
| | ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa) |
| | ENSPTRP00000089530 | annotation not available (141 aa) |
| | ENSPTRP00000088582 | annotation not available (66 aa) |
| | BAIAP2L1-2 | BAR/IMD domain containing adaptor protein 2 like 1. (502 aa) |
| | DBN1 | DBN1 isoform 1. (695 aa) |
| | ENSPTRP00000086247 | annotation not available (513 aa) |
| | ENSPTRP00000085830 | annotation not available (168 aa) |
| | ENSPTRP00000085141 | annotation not available (333 aa) |
| | ENSPTRP00000085116 | annotation not available (227 aa) |
| | ENSPTRP00000084862 | annotation not available (154 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) |
| | ARPC4 | Actin-related protein 2/3 complex subunit 4 isoform X4. (173 aa) |
| | ENSPTRP00000083809 | annotation not available (152 aa) |
| | FLII | FLII actin remodeling protein. (1273 aa) |
| | KIAA1211 | KIAA1211 isoform 3. (1233 aa) |
| | CTTN | CTTN isoform 2. (634 aa) |
| | LOC107971086 | Thymosin beta-15A isoform X2. (45 aa) |
| | ENSPTRP00000081955 | annotation not available (66 aa) |
| | CIT | Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2078 aa) |
| | SSH3 | Slingshot protein phosphatase 3. (658 aa) |
| | ENSPTRP00000078893 | annotation not available (168 aa) |
| | ENSPTRP00000078387 | annotation not available (202 aa) |
| | DBNL-2 | Drebrin like. (439 aa) |
| | LOC472932 | BCL2 associated athanogene 4 pseudogene. (356 aa) |
| | HIP1R | Huntingtin interacting protein 1 related. (1068 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | C15H15orf62 | Chromosome 15 C15orf62 homolog. (175 aa) |
| | SPTBN5 | LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 5. (3705 aa) |
| | TMSB4Y | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa) |
| | ARHGAP35 | Glucocorticoid receptor DNA binding factor 1. (1519 aa) |
| | SPTBN4 | Spectrin beta, non-erythrocytic 4. (2565 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa) |
| | CDC42EP2 | Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (210 aa) |
| | TWF1 | Twinfilin actin binding protein 1. (380 aa) |
| | DAAM2 | Dishevelled associated activator of morphogenesis 2. (1077 aa) |
| | ENSPTRP00000073763 | annotation not available (92 aa) |
| | ENSPTRP00000073520 | annotation not available (59 aa) |
| | RDX | RDX isoform 3. (609 aa) |
| | NEB | NEB isoform 5. (8417 aa) |
| | CAPZB | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa) |
| | CCL24-2 | C-C motif chemokine ligand 24. (119 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2366 aa) |
| | ENSPTRP00000070693 | annotation not available (228 aa) |
| | ENSPTRP00000070303 | annotation not available (117 aa) |
| | MLST8 | MLST8 isoform 3. (327 aa) |
| | ARF6 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | ENSPTRP00000069497 | annotation not available (53 aa) |
| | SWAP70 | SWAP70 isoform 1. (585 aa) |
| | WAS | WAS isoform 1. (502 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | ENSPTRP00000067847 | annotation not available (809 aa) |
| | ENSPTRP00000067474 | annotation not available (148 aa) |
| | KANK3 | KN motif and ankyrin repeat domains 3. (840 aa) |
| | COTL1 | Coactosin like F-actin binding protein 1. (163 aa) |
| | ENSPTRP00000066855 | annotation not available (256 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa) |
| | ENSPTRP00000066549 | annotation not available (154 aa) |
| | ENSPTRP00000065871 | annotation not available (255 aa) |
| | SNX9 | Sorting nexin. (596 aa) |
| | SPTAN1 | SPTAN1 isoform 9. (2498 aa) |
| | BAIAP2 | BAI1 associated protein 2. (553 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (631 aa) |
| | FMN1 | FMN1 isoform 1. (1425 aa) |
| | PFN3 | Profilin; Belongs to the profilin family. (137 aa) |
| | PAK3 | Serine/threonine-protein kinase PAK 3; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstrea [...] (580 aa) |
| | ENSPTRP00000062137 | annotation not available (195 aa) |
| | ENSPTRP00000062048 | annotation not available (257 aa) |
| | NPHS1 | NPHS1 isoform 1. (1241 aa) |
| | PLEKHG2 | Pleckstrin homology domain containing, family G (With RhoGef domain) member 2. (1386 aa) |
| | TRIOBP | TRIOBP isoform 1. (2139 aa) |
| | CAPZA1 | Capping actin protein of muscle Z-line subunit alpha 1. (325 aa) |
| | BBS4 | Bardet-Biedl syndrome 4. (519 aa) |
| | NAA80 | N(alpha)-acetyltransferase 80, NatH catalytic subunit. (308 aa) |
| | CK820_G0015929 | ARPC3 isoform 3. (178 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | SPTB | Spectrin beta chain; Belongs to the spectrin family. (2265 aa) |
| | PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1. (1364 aa) |
| | KANK4 | KN motif and ankyrin repeat domains 4. (995 aa) |
| | TMSB10 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa) |
| | ARHGAP28 | Rho GTPase activating protein 28. (729 aa) |
| | CDC42EP5 | CDC42 effector protein (Rho GTPase binding) 5. (148 aa) |
| | CAPZA2 | F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa) |
| | LMOD2 | LMOD2 isoform 1. (548 aa) |
| | TMSB4X | Thymosin beta 4 X-linked. (44 aa) |
| | KIRREL1 | Kirre like nephrin family adhesion molecule 1. (757 aa) |
| | ADD3 | Adducin 3 (Gamma). (706 aa) |
| | FCHSD1 | FCH and double SH3 domains 1. (690 aa) |
| | MTPN | MTPN isoform 1. (118 aa) |
| | KANK1 | KANK1 isoform 8. (1345 aa) |
| | SPTBN2 | Spectrin beta chain; Belongs to the spectrin family. (2390 aa) |
| | DMTN | Dematin actin binding protein. (405 aa) |
| | BAIAP2L1 | BAI1-associated protein 2-like 1. (511 aa) |
| | TMOD1 | TMOD1 isoform 1. (359 aa) |
| | CSF3 | Colony stimulating factor 3 (Granulocyte). (204 aa) |
| | TMSB15A | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa) |
| | MYO3B | MYO3B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1341 aa) |
| | TENM1 | Teneurin transmembrane protein 1. (2732 aa) |
| | ARPC5L | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa) |
| | GSN | GSN isoform 3. (782 aa) |
| | ABITRAM | FAM206A isoform 2. (181 aa) |
| | GBA2 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (927 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (134 aa) |
| | FAM49B | FAM49B isoform 13. (324 aa) |
| | ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited). (1849 aa) |
| | BAG4 | BCL2-associated athanogene 4. (457 aa) |
| | PTK2B | PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | ARPC1B | Actin related protein 2/3 complex, subunit 1A/1B. (372 aa) |
| | ARPC1A | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa) |
| | CCL24 | C-C motif chemokine ligand 24. (119 aa) |
| | CCL26 | C-C motif chemokine. (94 aa) |
| | DBNL | DBNL isoform 5. (439 aa) |
| | SCIN | SCIN isoform 3. (715 aa) |
| | LATS1 | LATS, large tumor suppressor, homolog 1. (1130 aa) |
| | ARHGAP18 | Rho GTPase activating protein 18. (663 aa) |
| | CARMIL1 | Capping protein regulator and myosin 1 linker 1. (1371 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | RASA1 | RAS p21 protein activator (GTPase activating protein) 1. (1047 aa) |
| | F2RL1 | F2R like trypsin receptor 1. (397 aa) |
| | SEMA5A | SEMA5A isoform 1. (1074 aa) |
| | WDR1 | WD repeat domain 1. (606 aa) |
| | ADD1 | ADD1 isoform 5. (768 aa) |
| | PFN2 | Profilin; Belongs to the profilin family. (188 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (484 aa) |
| | LMOD3 | LMOD3 isoform 1. (560 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | TWF2 | T0016682 isoform 2. (349 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | VILL | VILL isoform 1. (855 aa) |
| | BRK1 | BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa) |
| | BAIAP2L2 | BAIAP2L2 isoform 1. (518 aa) |
| | PDXP | Pyridoxal (Pyridoxine, vitamin B6) phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa) |
| | CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1. (391 aa) |
| | ARHGAP40 | Rho GTPase activating protein 40. (622 aa) |
| | HCK | Tyrosine-protein kinase. (526 aa) |
| | DSTN | Destrin (Actin depolymerizing factor); Belongs to the actin-binding proteins ADF family. (165 aa) |
| | MKKS | McKusick-Kaufman syndrome. (570 aa) |
| | VIL1 | VIL1 isoform 1. (827 aa) |
| | NCKAP1 | Nck-associated protein 1. (1128 aa) |
| | BIN1 | Bridging integrator 1. (597 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | CAPG | Capping actin protein, gelsolin like. (348 aa) |
| | PLEK | PLEK isoform 1. (350 aa) |
| | PLEKHH2 | PLEKHH2 isoform 5. (1457 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (129 aa) |
| | FAM49A | FAM49A isoform 1. (323 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | SSH2 | Slingshot protein phosphatase 2. (1450 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (140 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (662 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | TMOD3 | Tropomodulin 3 (Ubiquitous). (352 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | EVL | Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa) |
| | CFL2 | Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa) |
| | AVIL | AVIL isoform 2. (819 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1127 aa) |
| | LIMA1 | LIM domain and actin binding 1. (735 aa) |
| | CAPZA3 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa) |
| | EPS8 | Epidermal growth factor receptor pathway substrate 8. (822 aa) |
| | ESAM | Endothelial cell adhesion molecule. (390 aa) |
| | SVIL | SVIL isoform 6. (2214 aa) |
| | MYO3A | MYO3A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1621 aa) |
| | LMOD1 | LMOD1 isoform 2. (600 aa) |
| | ARPC5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa) |
| | SPTA1 | SPTA1 isoform 1. (2419 aa) |
| | HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa) |
| | TMOD4 | TMOD4 isoform 2. (345 aa) |
| | TMSB4X-2 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | ELN | ELN isoform 3. (790 aa) |
| | LOC104001050 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa) |
| | CK820_G0029270 | IQANK1 isoform 1. (91 aa) |
| | FHOD3 | Formin homology 2 domain containing 3. (1622 aa) |
| | ACTN2 | ACTN2 isoform 2. (894 aa) |
| | SLIT2 | Slit guidance ligand 2. (1542 aa) |
| | ADD2 | ADD2 isoform 1. (726 aa) |
