99 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPTRP00000090392	annotation not available (93 aa)
	ENSPTRP00000066719	annotation not available (71 aa)
	BASP1	Brain abundant, membrane attached signal protein 1. (226 aa)
	ENSPTRP00000069077	annotation not available (82 aa)
	CCDC14	CCDC14 isoform 12. (926 aa)
	EN2	Engrailed homeobox 2. (338 aa)
	WLS	Wnt ligand secretion mediator. (543 aa)
	EN2-2	Homeobox protein engrailed-like. (336 aa)
	TTBK1	Tau tubulin kinase 1. (1321 aa)
	ENSPTRP00000074655	annotation not available (67 aa)
	ENSPTRP00000075494	annotation not available (194 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	ENSPTRP00000076236	annotation not available (67 aa)
	WNT9B-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
	ENSPTRP00000076277	annotation not available (67 aa)
	FOXB1	FOXB1 isoform 3. (325 aa)
	CKB	Creatine kinase, brain; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	OTX2	Orthodenticle homeobox 2. (297 aa)
	CMA1	CMA1 isoform 1; Belongs to the peptidase S1 family. (252 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	KDM2B	Lysine (K)-specific demethylase 2B. (1336 aa)
	UQCRQ	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa. (82 aa)
	ENSPTRP00000076865	annotation not available (107 aa)
	CDC42	Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
	WNT3-2	Wnt family member 3. (290 aa)
	LOC107974864	Cytochrome b-c1 complex subunit 8. (82 aa)
	ENSPTRP00000082268	annotation not available (246 aa)
	ENSPTRP00000082446	annotation not available (194 aa)
	CALM1	CALM1 isoform 3; Belongs to the calmodulin family. (150 aa)
	ENSPTRP00000084510	annotation not available (456 aa)
	UCHL5	Ubiquitin carboxyl-terminal hydrolase. (393 aa)
	LOC459638	14-3-3 protein epsilon-like. (255 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	ENSPTRP00000086358	annotation not available (72 aa)
	FZD1	FZD1 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	ENSPTRP00000088766	annotation not available (199 aa)
	NR4A2	Nuclear receptor subfamily 4, group A, member 2. (598 aa)
	TAF1	Transcription initiation factor TFIID subunit. (1927 aa)
	SEC16A	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2358 aa)
	ENSPTRP00000090501	annotation not available (192 aa)
	FZD1-2	Frizzled class receptor 1. (580 aa)
	ENSPTRP00000093440	annotation not available (101 aa)
	ENSPTRP00000093753	Dynein light chain 1, cytoplasmic-like. (87 aa)
	SYPL2	Synaptophysin like 2. (272 aa)
	ATP5PF	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (119 aa)
	LOC469195	Dynein light chain 1, cytoplasmic-like. (89 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	ZNF148	Zinc finger protein 148. (794 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	MSX1	Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
	PADI2	Peptidyl arginine deiminase 2. (665 aa)
	HSPA5	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family. (654 aa)
	ATP5PB	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1. (256 aa)
	S100A1	Protein S100; Belongs to the S-100 family. (147 aa)
	LMX1A	LIM homeobox transcription factor 1 alpha. (382 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
	PITX3	Homeobox protein. (302 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	CASP5	CASP5 isoform 3; Belongs to the peptidase C14A family. (448 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	DYNLL1	Dynein light chain. (89 aa)
	SUDS3	SDS3 homolog, SIN3A corepressor complex component. (328 aa)
	LOC735377	Dynein light chain 1, cytoplasmic-like. (89 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	EN1	Homeobox protein engrailed-like. (396 aa)
	CD22-2	B-cell receptor CD22. (626 aa)
	NDST1	N-deacetylase/N-sulfotransferase (Heparan glucosaminyl) 1. (882 aa)
	PHOX2A	Paired like homeobox 2A. (284 aa)
	CTNNB1	Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
	FZD6	Frizzled homolog 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
	G6PD	Glucose-6-phosphate dehydrogenase. (560 aa)
	PLP1	Proteolipid protein 1. (277 aa)
	MAOB	Amine oxidase. (520 aa)
	BARHL1	BarH like homeobox 1. (327 aa)
	MAPKAP1	Mitogen-activated protein kinase associated protein 1. (522 aa)
	TAL2	TAL bHLH transcription factor 2. (108 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	KDM7A	Lysine demethylase 7A. (941 aa)
	WNT2	Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
	TFAP2D	Transcription factor AP-2 delta. (452 aa)
	RAD1	RAD1 isoform 1. (282 aa)
	SMAD1	Mothers against decapentaplegic homolog. (469 aa)
	GNB4	Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
	RYK	Receptor like tyrosine kinase. (610 aa)
	RHOA	Ras homolog family member A. (193 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; Belongs to the 14-3-3 family. (246 aa)
	OTX1	Orthodenticle homeobox 1. (354 aa)
	YWHAQ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Belongs to the 14-3-3 family. (253 aa)
	CALM3	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
	COX6B1	Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
	ZNF430	Zinc finger protein 430. (570 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	KAT2A	Histone acetyltransferase KAT2A isoform X1. (837 aa)
	CNP	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (421 aa)
	ENO3	Enolase 3 (Beta, muscle). (434 aa)
	YWHAE	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Belongs to the 14-3-3 family. (255 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5PB	ATP5PF	ENSPTRP00000001899	ENSPTRP00000093935	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	0.976
ATP5PB	ENSPTRP00000066719	ENSPTRP00000001899	ENSPTRP00000066719	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	annotation not available	0.540
ATP5PB	ENSPTRP00000086358	ENSPTRP00000001899	ENSPTRP00000086358	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	annotation not available	0.458
ATP5PB	ENSPTRP00000093440	ENSPTRP00000001899	ENSPTRP00000093440	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	annotation not available	0.976
ATP5PB	LOC107974864	ENSPTRP00000001899	ENSPTRP00000079731	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	Cytochrome b-c1 complex subunit 8.	0.458
ATP5PB	UQCRQ	ENSPTRP00000001899	ENSPTRP00000076713	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa.	0.458
ATP5PF	ATP5PB	ENSPTRP00000093935	ENSPTRP00000001899	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1.	0.976
ATP5PF	COX6B1	ENSPTRP00000093935	ENSPTRP00000018583	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B.	0.709
ATP5PF	ENSPTRP00000066719	ENSPTRP00000093935	ENSPTRP00000066719	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	annotation not available	0.976
ATP5PF	ENSPTRP00000074655	ENSPTRP00000093935	ENSPTRP00000074655	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	annotation not available	0.967
ATP5PF	ENSPTRP00000076236	ENSPTRP00000093935	ENSPTRP00000076236	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	annotation not available	0.967
ATP5PF	ENSPTRP00000076277	ENSPTRP00000093935	ENSPTRP00000076277	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	annotation not available	0.967
ATP5PF	ENSPTRP00000086358	ENSPTRP00000093935	ENSPTRP00000086358	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	annotation not available	0.640
ATP5PF	ENSPTRP00000093440	ENSPTRP00000093935	ENSPTRP00000093440	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	annotation not available	0.545
ATP5PF	LOC107974864	ENSPTRP00000093935	ENSPTRP00000079731	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	Cytochrome b-c1 complex subunit 8.	0.640
ATP5PF	UQCRQ	ENSPTRP00000093935	ENSPTRP00000076713	ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family.	Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa.	0.640
BARHL1	LMX1A	ENSPTRP00000036790	ENSPTRP00000002699	BarH like homeobox 1.	LIM homeobox transcription factor 1 alpha.	0.428
BASP1	HSPA5	ENSPTRP00000067678	ENSPTRP00000000984	Brain abundant, membrane attached signal protein 1.	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.	0.402
CALM1	CALM3	ENSPTRP00000082789	ENSPTRP00000019197	CALM1 isoform 3; Belongs to the calmodulin family.	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	0.772
CALM3	CALM1	ENSPTRP00000019197	ENSPTRP00000082789	Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family.	CALM1 isoform 3; Belongs to the calmodulin family.	0.772