STRINGSTRING
ITGA5 ITGA5 FGF9 FGF9 HIF1A HIF1A PRKCB PRKCB MT3 MT3 PRKD2 PRKD2 IL1B IL1B ARNT ARNT VEGFB VEGFB GRB10 GRB10 ITGB3 ITGB3 FGF10 FGF10 FGF18 FGF18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA5ITGA5 isoform 2; Belongs to the integrin alpha chain family. (1098 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MT3MT3 isoform 5; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
GRB10Growth factor receptor-bound protein 10. (594 aa)
ITGB3Integrin beta-3 isoform X2. (837 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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