STRINGSTRING
CK820_G0036362 CK820_G0036362 ERRFI1 ERRFI1 FGR FGR LCK LCK GNAI3 GNAI3 GNAT2 GNAT2 S100A6 S100A6 GNG4 GNG4 GNG3 GNG3 RACGAP1 RACGAP1 ESYT1 ESYT1 STAC3 STAC3 GNB5 GNB5 MYZAP MYZAP GRAMD2A GRAMD2A IQGAP1 IQGAP1 FES FES ALOX15 ALOX15 DLG4 DLG4 TNK1 TNK1 GNA13 GNA13 ZAP70 ZAP70 TGM3 TGM3 SNAP25 SNAP25 HCK HCK OSBPL2 OSBPL2 SRMS SRMS TIAM1 TIAM1 GNAZ GNAZ STAC STAC RHOA RHOA GNAT1 GNAT1 GNAI2 GNAI2 GNB4 GNB4 SNX18 SNX18 FER FER FRK FRK GNA12 GNA12 CYTH3 CYTH3 HIP1 HIP1 GNGT1 GNGT1 GNG11 GNG11 PTK2B PTK2B GNG10 GNG10 SYAP1 SYAP1 CDK16 CDK16 GNB3 GNB3 LYN LYN BLK BLK GNAQ GNAQ ESYT3 ESYT3 GNAT3 GNAT3 GNAS GNAS GNGT2 GNGT2 CAV2 CAV2 CYTH3-2 CYTH3-2 KCNAB1 KCNAB1 ESYT2 ESYT2 ENSPTRP00000062093 ENSPTRP00000062093 GNG12 GNG12 PTK6 PTK6 SLA SLA GNG13 GNG13 LOC104003639 LOC104003639 ENSPTRP00000063424 ENSPTRP00000063424 SHANK3 SHANK3 GNG2 GNG2 ENSPTRP00000065728 ENSPTRP00000065728 SNX9 SNX9 KCNAB2 KCNAB2 GNB1 GNB1 SNX5 SNX5 RAC1 RAC1 GNG7 GNG7 PLEKHA4 PLEKHA4 ENSPTRP00000070111 ENSPTRP00000070111 ENSPTRP00000071036 ENSPTRP00000071036 CBY3 CBY3 GNAI1 GNAI1 GRAMD1A GRAMD1A FARP1 FARP1 GNA11 GNA11 SYK SYK ENSPTRP00000075783 ENSPTRP00000075783 SRC SRC ENSPTRP00000077070 ENSPTRP00000077070 GNAL GNAL ENSPTRP00000077377 ENSPTRP00000077377 FYN FYN RGS1 RGS1 CYTH1 CYTH1 FERMT2 FERMT2 ENSPTRP00000081537 ENSPTRP00000081537 STYK1 STYK1 ENSPTRP00000081592 ENSPTRP00000081592 CYLD CYLD ENSPTRP00000082827 ENSPTRP00000082827 AKT1 AKT1 PTK2 PTK2 RAC1-2 RAC1-2 KRAS KRAS GNB2 GNB2 MCF2L-2 MCF2L-2 GNAO1 GNAO1 ENSPTRP00000088414 ENSPTRP00000088414 TNK2-2 TNK2-2 KCNIP1 KCNIP1 GNG8 GNG8 RGS8 RGS8 YES1 YES1 STAC2 STAC2 TNK2 TNK2 GNA14 GNA14 CARMIL2 CARMIL2 GNB2-2 GNB2-2 ENSPTRP00000093443 ENSPTRP00000093443 GNA15 GNA15 CK820_G0040666 CK820_G0040666 MCF2L MCF2L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CK820_G0036362MCF2L isoform 28. (83 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
FGRTyrosine-protein kinase. (529 aa)
LCKTyrosine-protein kinase. (539 aa)
GNAI3Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
S100A6Protein S100; Belongs to the S-100 family. (90 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
ESYT1Extended synaptotagmin-like protein 1. (1114 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
GNB5GNB5 isoform 1. (409 aa)
MYZAPGlutamate receptor, ionotropic, N-methyl D-aspartate-like 1A. (765 aa)
GRAMD2AGRAM domain containing 2A. (354 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
TNK1TNK1 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (661 aa)
GNA13Guanine nucleotide binding protein (G protein), alpha 13. (377 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
TGM3Transglutaminase 3. (693 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells; Belongs to the SNAP-25 family. (206 aa)
HCKTyrosine-protein kinase. (526 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (480 aa)
SRMSTyrosine-protein kinase. (447 aa)
TIAM1T-cell lymphoma invasion and metastasis 1. (1591 aa)
GNAZG protein subunit alpha z. (355 aa)
STACSH3 and cysteine rich domain. (402 aa)
RHOARas homolog family member A. (193 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
GNAI2Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (355 aa)
GNB4Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
SNX18Sorting nexin. (591 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
FRKTyrosine-protein kinase. (505 aa)
GNA12Guanine nucleotide binding protein (G protein) alpha 12. (381 aa)
CYTH3CYTH3 isoform 1. (399 aa)
HIP1HIP1 isoform 2. (1037 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
GNG10Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10. (68 aa)
SYAP1Synapse associated protein 1. (268 aa)
CDK16Cyclin dependent kinase 16. (570 aa)
GNB3G protein subunit beta 3. (340 aa)
LYNTyrosine-protein kinase. (512 aa)
BLKTyrosine-protein kinase. (505 aa)
GNAQGuanine nucleotide binding protein (G protein), q polypeptide. (359 aa)
ESYT3Extended synaptotagmin-like protein 3. (886 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
GNASGNAS isoform 19. (1042 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
CYTH3-2Cytohesin 3. (399 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
ESYT2ESYT2 isoform 1. (897 aa)
ENSPTRP00000062093annotation not available (1025 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PTK6Tyrosine-protein kinase. (451 aa)
SLASrc like adaptor. (316 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
LOC104003639Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa)
ENSPTRP00000063424annotation not available (1563 aa)
SHANK3SHANK3 isoform 2. (1744 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
ENSPTRP00000065728annotation not available (516 aa)
SNX9Sorting nexin. (596 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
GNB1Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLEKHA4Pleckstrin homology domain containing, family A (Phosphoinositide binding specific) member 4. (779 aa)
ENSPTRP00000070111annotation not available (324 aa)
ENSPTRP00000071036annotation not available (68 aa)
CBY3Chibby family member 3. (242 aa)
GNAI1Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. (422 aa)
GRAMD1AGRAM domain containing 1A. (812 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1076 aa)
GNA11Guanine nucleotide binding protein (G protein), alpha 11 (Gq class). (359 aa)
SYKTyrosine-protein kinase. (635 aa)
ENSPTRP00000075783annotation not available (149 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSPTRP00000077070annotation not available (669 aa)
GNALG protein subunit alpha L. (458 aa)
ENSPTRP00000077377annotation not available (149 aa)
FYNTyrosine-protein kinase. (537 aa)
RGS1Regulator of G protein signaling 1. (209 aa)
CYTH1CYTH1 isoform 3. (399 aa)
FERMT2Fermitin family member 2. (706 aa)
ENSPTRP00000081537annotation not available (449 aa)
STYK1Serine/threonine/tyrosine kinase 1. (422 aa)
ENSPTRP00000081592annotation not available (837 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
ENSPTRP00000082827annotation not available (151 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
GNB2Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
MCF2L-2MCF2L isoform 7. (395 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ENSPTRP00000088414annotation not available (529 aa)
TNK2-2Tyrosine kinase non receptor 2. (86 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (241 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
RGS8Regulator of G protein signaling 8. (198 aa)
YES1Tyrosine-protein kinase. (558 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
TNK2TNK2 isoform 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
GNA14Guanine nucleotide binding protein (G protein), alpha 14. (355 aa)
CARMIL2CARMIL2 isoform 2. (1436 aa)
GNB2-2G protein subunit beta 2. (372 aa)
ENSPTRP00000093443annotation not available (57 aa)
GNA15G protein subunit alpha 15. (374 aa)
CK820_G0040666Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
MCF2LMCF2L isoform 9. (1202 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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