STRINGSTRING
TMEM109 TMEM109 CAMK2G CAMK2G CK820_G0029100 CK820_G0029100 RYR1 RYR1 KLHL41 KLHL41 RYR3 RYR3 CK820_G0030361 CK820_G0030361 SRL SRL CAMK2D CAMK2D TMEM38B TMEM38B SLN SLN ENSPTRP00000085680 ENSPTRP00000085680 REEP5 REEP5 ATP2A1 ATP2A1 SRI-2 SRI-2 SRI SRI STIM1 STIM1 PLN PLN CAMK2B CAMK2B STRIT1 STRIT1 DMPK DMPK SYNE2 SYNE2 MRLN MRLN RYR2 RYR2 RTN2 RTN2 JPH2 JPH2 ENSPTRP00000061732 ENSPTRP00000061732 JPH4 JPH4 TRDN TRDN JPH3 JPH3 ASPH ASPH JPH1 JPH1 ATP2A3 ATP2A3 NOS1AP NOS1AP ITPR2 ITPR2 FKBP1B FKBP1B TMEM38A TMEM38A CHERP CHERP JSRP1 JSRP1 DHRS7C DHRS7C AKAP6 AKAP6 ATP2A2 ATP2A2 ART1 ART1 CASQ1 CASQ1 CASQ2 CASQ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM109Transmembrane protein 109. (243 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase II gamma. (562 aa)
CK820_G0029100SRI isoform 2. (98 aa)
RYR1RYR1 isoform 3. (5037 aa)
KLHL41Kelch repeat and BTB domain-containing protein 5/10. (606 aa)
RYR3Ryanodine receptor 3. (4873 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
SRLSRL isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (931 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
TMEM38BTransmembrane protein 38B. (297 aa)
SLNSLN isoform 1. (31 aa)
ENSPTRP00000085680annotation not available (88 aa)
REEP5Receptor expression-enhancing protein. (257 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1068 aa)
SRI-2SRI isoform 5. (237 aa)
SRISRI isoform 1. (205 aa)
STIM1Stromal interaction molecule 1. (791 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
DMPKDystrophia myotonica-protein kinase. (639 aa)
SYNE2SYNE2 isoform 1. (6907 aa)
MRLNMRLN isoform 2. (46 aa)
RYR2RYR2 isoform 1. (4941 aa)
RTN2Reticulon. (545 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
ENSPTRP00000061732annotation not available (285 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
TRDNTRDN isoform 1. (730 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
ASPHASPH isoform 1. (762 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (506 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
TMEM38ATransmembrane protein 38A. (299 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (917 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (331 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ART1NAD(P)(+)--arginine ADP-ribosyltransferase. (327 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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