29 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAG2	Recombination activating 2. (527 aa)
	TESPA1	TESPA1 isoform 6. (521 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	FOXN1	FOXN1 isoform 2. (648 aa)
	FOXJ1	FOXJ1 isoform 1. (421 aa)
	CLEC4G	C-type lectin domain family 4 member G. (293 aa)
	CLPTM1	CLPTM1 regulator of GABA type A receptor forward trafficking. (669 aa)
	ZC3H8	Zinc finger CCCH-type containing 8. (291 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	TMEM131L	TMEM131L isoform 3. (1617 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
	VNN1	VNN1 isoform 1. (513 aa)
	VNN3	VNN3 isoform 1. (501 aa)
	EGR3	Early growth response 3. (387 aa)
	TOX	Thymocyte selection-associated high mobility group box. (526 aa)
	GLI2	GLI family zinc finger 2. (1587 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
	IL2RG	IL2RG isoform 1. (369 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1127 aa)
	ADAM8	ADAM metallopeptidase domain 8. (824 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	RASGRP1	RASGRP1 isoform 4. (848 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (421 aa)
	ADA	Adenosine deaminase. (412 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	IL7R	Interleukin 7 receptor. (459 aa)
	CDKN2A	Cyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4). (173 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	IL2RG	ENSPTRP00000073897	ENSPTRP00000047375	Adenosine deaminase.	IL2RG isoform 1.	0.506
BMP4	IHH	ENSPTRP00000010780	ENSPTRP00000022106	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.421
BMP4	SHH	ENSPTRP00000010780	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
BMP4-2	IHH	ENSPTRP00000080656	ENSPTRP00000022106	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.421
BMP4-2	SHH	ENSPTRP00000080656	ENSPTRP00000075730	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.720
ERBB2	GLI2	ENSPTRP00000069840	ENSPTRP00000040313	Receptor protein-tyrosine kinase.	GLI family zinc finger 2.	0.419
ERBB2	PTPN2	ENSPTRP00000069840	ENSPTRP00000072838	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type.	0.475
ERBB2	SHH	ENSPTRP00000069840	ENSPTRP00000075730	Receptor protein-tyrosine kinase.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.469
ERBB2	SOS1	ENSPTRP00000069840	ENSPTRP00000052023	Receptor protein-tyrosine kinase.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.786
ERBB2	SOS2	ENSPTRP00000069840	ENSPTRP00000043790	Receptor protein-tyrosine kinase.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.750
ERBB2	ZEB1	ENSPTRP00000069840	ENSPTRP00000062768	Receptor protein-tyrosine kinase.	Zinc finger E-box binding homeobox 1.	0.467
FOXJ1	SHH	ENSPTRP00000016444	ENSPTRP00000075730	FOXJ1 isoform 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.488
FOXN1	RAG2	ENSPTRP00000015225	ENSPTRP00000006100	FOXN1 isoform 2.	Recombination activating 2.	0.415
GLI2	ERBB2	ENSPTRP00000040313	ENSPTRP00000069840	GLI family zinc finger 2.	Receptor protein-tyrosine kinase.	0.419
GLI2	IHH	ENSPTRP00000040313	ENSPTRP00000022106	GLI family zinc finger 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.770
GLI2	RASGRP1	ENSPTRP00000040313	ENSPTRP00000072820	GLI family zinc finger 2.	RASGRP1 isoform 4.	0.436
GLI2	SHH	ENSPTRP00000040313	ENSPTRP00000075730	GLI family zinc finger 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.846
IHH	BMP4	ENSPTRP00000022106	ENSPTRP00000010780	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.421
IHH	BMP4-2	ENSPTRP00000022106	ENSPTRP00000080656	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.421
IHH	GLI2	ENSPTRP00000022106	ENSPTRP00000040313	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	GLI family zinc finger 2.	0.770