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PINK1 | PTEN induced putative kinase 1. (581 aa) | ||||
MAD2L2 | MAD2 mitotic arrest deficient-like 2. (211 aa) | ||||
OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa) | ||||
HAX1 | HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa) | ||||
SMYD3 | SET and MYND domain containing 3. (428 aa) | ||||
RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1116 aa) | ||||
ERCC6 | ERCC6 isoform 1. (1491 aa) | ||||
STOX1 | STOX1 isoform 1. (887 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (553 aa) | ||||
IAPP | Islet amyloid polypeptide. (89 aa) | ||||
RAPGEF3 | Rap guanine nucleotide exchange factor 3. (923 aa) | ||||
TBK1 | TANK-binding kinase 1. (729 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa) | ||||
SPRY2 | Sprouty homolog 2. (338 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (873 aa) | ||||
TCL1A | T cell leukemia/lymphoma 1A. (114 aa) | ||||
TERF2IP | Telomeric repeat binding factor 2, interacting protein. (399 aa) | ||||
ARRB2 | ARRB2 isoform 2. (430 aa) | ||||
RPTOR | Regulatory associated protein of MTOR, complex 1. (1324 aa) | ||||
SH2D3A | SH2 domain containing 3A. (576 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
GSK3A | Glycogen synthase kinase 3 alpha. (483 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) | ||||
NTF4 | NTF4 isoform 1; Belongs to the NGF-beta family. (210 aa) | ||||
IL11 | IL11 isoform 1. (199 aa) | ||||
UCN | UCN isoform 1. (124 aa) | ||||
AVP | Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa) | ||||
LIF | Leukemia inhibitory factor (Cholinergic differentiation factor). (202 aa) | ||||
OSM | OSM isoform 1. (252 aa) | ||||
HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (484 aa) | ||||
PFN2 | Profilin; Belongs to the profilin family. (188 aa) | ||||
PDCD10 | Programmed cell death 10. (212 aa) | ||||
EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1. (1559 aa) | ||||
SFRP2 | Secreted frizzled-related protein 2. (295 aa) | ||||
HSP90AB1 | HSP90AB1 isoform 1. (688 aa) | ||||
LATS1 | LATS, large tumor suppressor, homolog 1. (1130 aa) | ||||
RAMP3 | Receptor activity modifying protein 3. (151 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
BAG4 | BCL2-associated athanogene 4. (457 aa) | ||||
IFNB1 | Interferon beta 1. (187 aa) | ||||
IFNA21 | Interferon alpha 21. (189 aa) | ||||
IFNA5 | Interferon alpha 5. (189 aa) | ||||
IFNE | Interferon, epsilon. (208 aa) | ||||
IFNK | IFNK isoform 1. (208 aa) | ||||
TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) | ||||
MAPKAP1 | Mitogen-activated protein kinase associated protein 1. (522 aa) | ||||
SH2D3C | SH2 domain containing 3C. (860 aa) | ||||
HDAC6 | Histone deacetylase 6. (146 aa) | ||||
TENM1 | Teneurin transmembrane protein 1. (2732 aa) | ||||
CSF3 | Colony stimulating factor 3 (Granulocyte). (204 aa) | ||||
AXIN1 | AXIN1 isoform 2. (859 aa) | ||||
TNKS1BP1 | Tankyrase 1 binding protein 1. (1729 aa) | ||||
TFRC | Transferrin receptor (P90, CD71). (760 aa) | ||||
AKAP9 | A kinase (PRKA) anchor protein (Yotiao) 9. (3908 aa) | ||||
GCG | GCG isoform 1. (180 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
MTCP1 | Mature T cell proliferation 1. (107 aa) | ||||
BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa) | ||||
IFNA6 | Interferon alpha 6. (190 aa) | ||||
ENSPTRP00000062048 | annotation not available (257 aa) | ||||
CNOT9 | CCR4-NOT transcription complex subunit 9. (331 aa) | ||||
STK4 | Serine/threonine-protein kinase 4. (487 aa) | ||||
AKAP9-2 | A-kinase anchoring protein 9. (3896 aa) | ||||
FNIP1 | Folliculin-interacting protein 1 isoform X1. (1166 aa) | ||||
IL6 | Interleukin 6 (Interferon, beta 2). (234 aa) | ||||
IFNA17 | IFNA17 isoform 1. (189 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (551 aa) | ||||
ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) | ||||
TCL1B | T cell leukemia/lymphoma 1B. (128 aa) | ||||
NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) | ||||
ENSPTRP00000070902 | annotation not available (168 aa) | ||||
IFNA14 | Interferon alpha 14. (189 aa) | ||||
DOCK7 | Dedicator of cytokinesis 7; Belongs to the DOCK family. (2129 aa) | ||||
NRXN1 | NRXN1 isoform 9. (1547 aa) | ||||
CALCR | Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa) | ||||
CREBL2 | cAMP-responsive element-binding protein-like 2. (193 aa) | ||||
IRGM | Immunity-related GTPase M. (214 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
LOC472932 | BCL2 associated athanogene 4 pseudogene. (356 aa) | ||||
PARK7 | PARK7 isoform 1. (189 aa) | ||||
BRAF | BRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa) | ||||
IL6-2 | Interleukin 6. (234 aa) | ||||
CK820_G0014527 | IFNA13 isoform 2. (198 aa) | ||||
AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) | ||||
FNIP2 | Folliculin interacting protein 2. (1167 aa) | ||||
BCAR3 | Breast cancer anti-estrogen resistance 3. (825 aa) | ||||
ARAF | V-raf murine sarcoma 3611 viral oncogene homolog. (606 aa) | ||||
IFNA8 | Interferon alpha 8. (189 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) | ||||
LOC741747 | IFNA7 isoform 1. (189 aa) | ||||
ENSPTRP00000085116 | annotation not available (227 aa) | ||||
NTRK3 | NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa) | ||||
CAMK1 | Calcium/calmodulin-dependent protein kinase I; Belongs to the protein kinase superfamily. (380 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
RAF1 | RAF1 isoform 2; Belongs to the protein kinase superfamily. (668 aa) | ||||
BRAF-2 | BRAF isoform 2. (766 aa) | ||||
CAPRIN2 | Caprin family member 2. (1077 aa) | ||||
LOC742651 | IFNA1 isoform 1. (195 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
ENSPTRP00000090382 | annotation not available (493 aa) | ||||
MIF | Macrophage migration inhibitory factor. (115 aa) | ||||
CD44 | CD44 isoform 3. (742 aa) | ||||
SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (140 aa) | ||||
ANGPT1 | ANGPT1 isoform 2. (498 aa) | ||||
NOS1 | Nitric oxide synthase 1. (1468 aa) | ||||
IFNW1 | IFNW1 isoform 1. (200 aa) | ||||
APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (771 aa) |