STRINGSTRING
PTGS2 PTGS2 P2RY2 P2RY2 PANX1 PANX1 P2RX4 P2RX4 CIB2 CIB2 TRPV1 TRPV1 P2RX1 P2RX1 TRPM4 TRPM4 IL1B IL1B P2RX6 P2RX6 PDXP PDXP P2RY1 P2RY1 NT5E NT5E KCNJ11 KCNJ11 P2RY11 P2RY11 ENPP1 ENPP1 P2RX7 P2RX7 ASPH ASPH P2RX5 P2RX5 TRPC3 TRPC3 PKLR PKLR CK820_G0015936 CK820_G0015936 P2RY4 P2RY4 P2RX3 P2RX3 CK820_G0042363 CK820_G0042363 SLC8A1 SLC8A1 LOC457015 LOC457015 ENSPTRP00000074534 ENSPTRP00000074534 HSP90B1 HSP90B1 DGKQ DGKQ P2RX2 P2RX2 ABCC9 ABCC9 ENSPTRP00000085296 ENSPTRP00000085296 ENSPTRP00000089993 ENSPTRP00000089993 SSH1 SSH1 TAF1 TAF1 RYR3 RYR3 ENSPTRP00000091352 ENSPTRP00000091352
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGS2Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase). (604 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (346 aa)
CIB2Calcium and integrin binding family member 2. (187 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
TRPM4Transient receptor potential cation channel, subfamily M, member 4. (1306 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (441 aa)
PDXPPyridoxal (Pyridoxine, vitamin B6) phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
NT5E5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (574 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
P2RY11Purinergic receptor P2Y11. (374 aa)
ENPP1ENPP1 isoform 1. (925 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
ASPHASPH isoform 1. (762 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (431 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
CK820_G0015936C12orf76 isoform 1. (107 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
CK820_G0042363TRPM4 isoform 1. (1251 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
LOC457015LOW QUALITY PROTEIN: endoplasmin-like. (448 aa)
ENSPTRP00000074534annotation not available (441 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
DGKQDiacylglycerol kinase. (952 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (497 aa)
ABCC9ATP-binding cassette, sub-family C (CFTR/MRP), member 9. (1549 aa)
ENSPTRP00000085296Uncharacterized protein LOC107966511 isoform X1. (87 aa)
ENSPTRP00000089993annotation not available (58 aa)
SSH1Slingshot homolog 1. (1062 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
RYR3Ryanodine receptor 3. (4873 aa)
ENSPTRP00000091352annotation not available (87 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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