STRINGSTRING
STAT6 STAT6 PHB2 PHB2 WNT5A WNT5A CCND1 CCND1 CEBPB CEBPB ENSPTRP00000084126 ENSPTRP00000084126 AGAP2 AGAP2 BTRC BTRC AREG AREG IQGAP3 IQGAP3 ESR1 ESR1 MAPK1 MAPK1 TNFSF11 TNFSF11 MED1 MED1 EPHA2 EPHA2 ID2 ID2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT6Signal transducer and activator of transcription. (847 aa)
PHB2Prohibitin. (299 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CCND1CCND1 isoform 1; Belongs to the cyclin family. (295 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
ENSPTRP00000084126annotation not available (117 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1192 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
AREGAREG isoform 2. (274 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1589 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
EPHA2EPH receptor A2. (976 aa)
ID2Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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